14 - Colon, Rectum, and Anus Flashcards
Most common site of metastasis of colorectal cancers:
liver
Most common type of neoplastic colonic polyp:
tubular adenoma
Identify: types of inflammatory bowel disease: -which of these is more related to the development of colorectal cancer than the other?
-ulcerative colitis -Crohn’s disease -ulcerative colitis
Age at which screening for colorectal cancer is started:
45 years
Most common genetic defect leading to sporadic colorectal cancer is:
APC
What week does embryonic GI tract begin developing
4th week of gestation
Most common bacteria in the colon
B. Fragilis
Diagnostic test used if perforation or leak is suspected in the colon
Gastrografin - water soluble contrast agent
How can ultrasound differentiate a benign polyp from invasive tumor?
Based on integrity of the submucosal layer
Most common traumatic cause of incontinence
Injury to the anal sphincter during vaginal delivery
Most common site of diverticulosis
sigmoid colon
Most common fistula of diverticulitis
colovesical fistula (5%)
hinchey staging for complicated diverticulitiys
I - pericolic abscess II - pelvic abscess III - purulent peritonitis IV - fecal peritonitis
Diagnostic test for diverticulitis
CT scan
Treatment of uncomplicated diverticulitis
- out patient 2. broad spectrum antibiotic 7 to 10 days 3. low residue diet 4. failure to improve in 48 to 72 hours indicates abscess formation
Treatment of complicated diverticulitis
Elective sigmoid colectomy
What gene is mutated in familial aadenomatous polyposis
APC gene - chromosome 5