(13) - Zygomycosis

Question 1

1. Zygomycetes are ubiquitous saprophytes of soil, water and decaying vegetation and it is a
   component of the normal flora of the skin and hair coat.
2. Zygomycetes penetrate the body how?

Answer 1

2. via respiratory or gastrointestinal tract or wound contamination

Question 2

1. Which two zygomycete ordes can cause disease?

Answer 2

1. Mucorales & Entomophthorales

Question 3

1.  Cytology of aspirates or direct smears and skin biopsies reveal a pyogranulomatous
   inflammation with the presence of wide, thin-walled, occasionally septate hyphae.
2. The organisms grow in Sabouraud’s agar.
3. What are the preferred material for culture?

Answer 3

3. Excision biopsies and/or leeches

Question 4

1. Surgical excision or debulking may be followed by chemotherapy based on susceptibility
   testing.
2. Potassium or sodium iodide, amphotericin B, miconazole, itraconazole can be used.

Answer 4

d