13 Meiosis Flashcards
When does meiosis I begin?
Meiosis begins after chromosomes are replicated during S phase and the cell moves through G2 phase
Early Prophase I
nuclear envelope begins to break down, chromosomes condense, the spindle apparatus begins to form, then synapsis occurs
Synapsis
homologous chromosome pairs come together, usually requires breaking and connecting DNA of 2 homology at many spots along their length, creating a bivalent
Bivalent
consists of paired homologous replicated chromosomes, where each homolog consists of two sister chromatids
Late Prophase I
nuclear envelope breaks down, and the two homologs within each bivalent become attached to microtubules coming from opposing poles of the spindle apparatus
Chiasmata/Chiasma
X-shaped structures that help hold homologous chromosomes together during Meiosis I and are a way in which Meiosis creates genetic diversity
Crossing Over
process of exchange in the parts of genetic material between non-sister chromatids of maternal and paternal homologs at each chiasma after synapsis
Metaphase I
kinetochore microtubules move the pairs of homologous chromosomes (bivalents) to a region called the metaphase plate where they are independently aligned
Metaphase plate
an imaginary plane midway between the poles of the spindle apparatus
Anaphase I
homologous chromosomes in each bivalent separate from each other as they are moved to opposite poles of the spindle apparatus
Telophase I
homologs finish moving to opposite sides of the spindle, cytokinesis occurs, forming two haploid daughter cells
What happens to the chromosome number of daughter cells after Meiosis I?
reduces and the cells become haploid, having only one copy of each type of chromosome
What does Meiosis II do?
separate the sister chromatids of the replicated chromosomes into separate cells so each will contain unreplicated daughter chromosomes
Prophase II
a spindle apparatus forms in both daughter cells, nuclear envelope breaks apart, chromosomes move toward the middle of each cell
Metaphase II
each chromosome is attached by microtubules to both poles and are lined up at the metaphase plate
Anaphase II
sister chromatids of each chromosome are separated and become independent daughter chromosomes
Telophase II
chromosomes move to different daughter cells forming 4 haploid cells each with 1 daughter chromosome of each type in the chromosome set
What are the stages in Prophase I?
(1) Condensation of Chromosomes as sister chromatids are held by cohesins (2) Synapsis where bivalent is held by synaptonemal complex (3) Breaks in DNA lead to crossover between non-sister chromatids (4) Synaptonemal complex disassembles as 2 homologs are held at the chiasmata until it breaks and leaves 2 unconnected chromosomes