12 Cell Cycle Flashcards

1
Q

Mitosis

A

“thread,” chromosomes condense into compact structures that can be moved around the cell efficiently then one copy of each chromosome is distributed to each of two daughter cells

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2
Q

Chromosome

A

“coloured body,” thread-like structures consisting of a single long DNA double helix wrapped around proteins called histones in a highly organized manner

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3
Q

Gene

A

a region of DNA in a chromosome that codes for a particular protein or ribonucleic acid

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4
Q

Centromeres

A

DNA region that functions as a handle on a chromosome

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5
Q

M phase (Mitotic or Meiotic)

A

Cells are in the process of separating their chromosomes

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6
Q

Interphase

A

Cells are either growing and preparing to divide or fulfilling its specialized function in a multicellular individual; Chromosomes are loosely dispersed in the nucleus

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7
Q

When does DNA replication occur?

A

S (Synthesis) phase in the Interphase

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8
Q

Cell Cycle

A

Orderly sequence of events that leads a eukaryotic cell through the duplication of its chromosomes to the time it divides

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9
Q

What happens in gaps 1 and 2 in the cell cycle?

A

Cells grow and replicate organelles so it will be able to divide into two cells that can function normally

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10
Q

Chromatins

A

DNA-protein (histone protein) complex which form chromosomes within an interphase nucleus

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11
Q

Cohesins

A

Large number of protein rings at the centromeres that hold sister chromatids together until a signal is given and they become independent chromosomes

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12
Q

Kinectochores

A

site where microtubules (in the cytosol) connect to chromosomes by forming an interface between chromosomes and inside of nuclear envelope

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13
Q

Condensins

A

ring-shaped proteins along the length of chromosomes that compact them for mitosis; encircles DNA and stabilizes loops in the same piece of DNA

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14
Q

What 5 proteins does DNA work with in mitosis?

A

cohesins, microtubules, kinetochore, nuclear lamins, condensins

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15
Q

What are the 5 subphases within M phase?

A

prophase, prometaphase, metaphase, anaphase, telophase

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16
Q

Centrosomes

A

located in animal and fungal cells, microtubule-organizing centres or large protein complexes that contain small bundles of microtubules known as centrioles

17
Q

Prophase

A

When chromosomes condense into compact structures, marked by the formation of spindle apparatus

18
Q

Spindle apparatus

A

Consists of distinct populations of microtubules anchored at their base to a centrosome (in an animal cell) or NEDD1 complex (in a plant cell)

19
Q

What does a spindle apparatus do?

A

Produces mechanical forces that (1) pull chromosomes to the poles of the cell during mitosis and (2) push the poles of the cell away from each other

20
Q

Types of spindle apparatus

A

polar, kinetochore, astral

21
Q

Polar microtubules

A

extend outwards and overlap with other polar microtubules attached to the opposite MTOC

22
Q

Kinetochore microtubules

A

proteins at the centromeres that hold the DNA and microtubules together

23
Q

Astral microtubules

A

found only in animal cells and connect the centrosome to proteins on the inner surface of the plasma membrane

24
Q

Prometaphase

A

Nuclear envelope begins to disappear and chromosomes move to the middle of the cell after kinetochores attach to microtubules

25
Q

Metaphase

A

chromosomes are lined up along an imaginary plane between the two spindle poles called the metaphase plate and formation of spindle apparatus is complete; tug of war occurs between sister chromatids

26
Q

Anaphase

A

cohesins holding sister chromatids together split into two identical sets of daughter chromosomes to opposite poles

27
Q

Telophase

A

nuclear envelope that dissolved in prometaphase reforms around each set of chromosomes and the chromosomes begin to de-condense; 2 independent nuclei forms

28
Q

Sister chromatids

A

2 identical pieces of DNA (same alleles) held together by a centromere which are found in a chromosome after DNA replication

29
Q

Microtubules

A

proteins with many functions like moving chromosomes during mitosis

30
Q

Nuclear lamins

A

intermediate filaments on the inner surface of the nuclear envelope that hold the nucleus together during interphase

31
Q

NEDD1 complexes

A

microtubule-organizing centres used in plant cells during mitosis

32
Q

Locus (plural: loci)

A

location of a gene on a chromosome

33
Q

Genotype

A

combo of alleles for all genes of interest

34
Q

Cytokinesis

A

cytoplasm of the parental cell is divided into two daughter cells each with its own nucleus and set of organelles