13 Fungus Drug Table Dosing

Question 1

How is Amphotericin B (Fungizone) dosed?

Answer 1

0.25-1mg/kg/day. Treatment duration: total dose 1-2g (3-4 weeks)

Question 2

How is Abelcet dosed?

Answer 2

5mg/kg/day

Question 3

How is Amphotec dosed?

Answer 3

3-4mg/kg/day

Question 4

How is Ambisome dosed?

Answer 4

3-5mg/kg/day

Question 5

How is Ketoconazole dosed?

Answer 5

Serious infection: 800mg PO QD

Normal: 200-400mg PO QD

Question 6

How is Fluconazole dosed for Vulvovaginal candida?

Answer 6

150mg x1

Question 7

How is Fluconazole dosed for Mucosal candidiasis?

Answer 7

100-200mg/day

Question 8

How is Fluconazole dosed for systemic infection?

Answer 8

400-800mg/day

Question 9

How is Fluconazole dosed for Cryptococcal meningitis maintenance?

Answer 9

400mg/day

Question 10

How is Itraconazole dosed for Onchomycosis?

Answer 10

200mg QD

Question 11

How is Itraconazole dosed for Aspergillus?

Answer 11

200mg Q12h

Question 12

How is Voriconazole dosed?

Answer 12

Always start with IV: 6mg/kg IV Q12h load x2, 4mg/kg Q12h maintenance. If PO: 200mg PO Q12h

Question 13

How is Pozaconazole dosed?

Answer 13

800mg QD in 2-4 divided doses (200mg Q6h)

Question 14

How is Flucytosine dosed?

Answer 14

50-150mg/kg/day (4 divided doses). Adjust for renal insufficiency

Question 15

How is Caspofungin dosed?

Answer 15

70mg x1 LD, then 50mg QD

Question 16

How is Micafungin dosed for Candidial Prophylaxis?

Answer 16

50mg/day

Question 17

How is Micafungin dosed for Esophageal Candidiasis?

Answer 17

150mg/day

Question 18

How is Micafungin dosed for Candidemia?

Answer 18

100mg/day

Question 19

How is Anidulafungin dosed for Esophageal Candidiasis?

Answer 19

100mg x1, then 50mg QD

Question 20

How is Anidulafungin dosed for Invasive Candidiasis?

Answer 20

200mg x1, then 100mg QD