[13] FINALS | DRUGS ACTING ON CARDIOVASCULAR SYSTEM Flashcards

1
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

HEART
Conduction of electrical impulse
Regulation of heart rate, blood flow, and blood circulation

These groups of drug regulate:
Heart contraction
Heart rate and rhythm
Blood flow to the myocardium (heart muscle)

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2
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

CARDIAC GLYCOSIDES
Digitalis
* 1785 - used to alleviate “dropsy” (edema of the extremities)
* Effective in treating CHF
* Inhibits the Na-K pump thus increase intracellular Ca causes muscle fibers to contract more efficiently.
* Inhibits the Na-K pump
promoting increase force of
cardiac contraction, cardiac
output, tissue perfusion,
decreases ventricular rate

Effects on the Heart Muscle
1. Positive inotropic action
2. Negative chronotropic action
3. Negative dormotropic action
4. Used to correct atrial fibrillation and atrial flutter

C/I
* Dysrhythmias
* AMI
* Renal disease
* Hypokalemia

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3
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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4
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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5
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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6
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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7
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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8
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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9
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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10
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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11
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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12
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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13
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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14
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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15
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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16
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CARDIOTONIC ANTIANGINALS AND ANTIDYSRHYTHMICS

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