12.11 Haemoglobin Flashcards
Haemoglobin is…
Complex protein with a quaternary structure composed of 4 polypeptide units
Each contain a harm group
Affinity means
Chemical attraction
Haemoglobin has an affinity to…
Oxygen
To be efficient at transporting oxygen Haemoglobin must…
Readily associate with oxygen at gas exchange surface and dissociate oxygen at respiring cells
Percentage saturation of Haemoglobin with oxygen =
Oxygenate Haemoglobin/maximum saturation x 100
Oxygen dissociation curve definition
Partial pressure of Oxygen
Loading
When oxygen is taken up by Haemoglobin
Unloading
When oxygen is given up by Haemoglobin
Partial pressure of O2 is higher in…
Capillaries
What is the s shaped curve described as
Sigmund curve
the pO2 in the tissue capillaries is…
Lower only about 5 kPa
Tissue cells respire…
Aerobically quickly reducing the dissolved O2 surrounding the tissue fluid
This reduces the PO2 to
A lower level than normal