12. Signalling Pathways in practise Flashcards

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1
Q

where are smells detected within the nasal cavity

A

the olfactory epithelium

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2
Q

what type of receptors are involved in smell perception

A

GPCRs

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3
Q

describe the odorant perception signalling pathway:

A
  1. odorant molecule interacts with the GPCR
  2. activates a G-protein which exchanges GDP for GTP
  3. Alpha subunit of GTP associates with adenylate cyclase
  4. adenylate cyclase converts ATP into cAMP
  5. cAMP activates cation channels = depolarisation
  6. calcium also enters the cell activation an anion channel = allows chloride efflux
  7. further depolarisation
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4
Q

where is calcium-ABA signalling important

A

in guard cells

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5
Q

what does ABA induce

A

an increase in cytosolic calcium levels

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6
Q

how does calcium work to depolarise the membrane

A

inhibits K+ channels
inhibits H+ ATPase - no longer pumping out cations
activate anion channels =anion efflux
activates vacuole K+ channels = potassium efflux from the vacuole into the cytosol

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7
Q

what repolarises the membrane

A

depolarisation activates K+ channels that allow K+ to leave the cell

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