1.2: Genetics and Heredity Flashcards
What is DNA?
Genetic ‘instruction manual’
Double-helix structure of base pairs (nucleotides)
Contained in chromosomes in the cell nucleus, also in mitochondria
How many chromosomes and base pairs do humans have?
46 chromosomes
Approx. 3 billion base pairs
Coding DNA
Information on chains of amino acids that dictates protein structure
Coding DNA makes up 1-2% of the genome
Non-coding DNA
Has regulatory functions
What are proteins for? (5)
Muscle Amylase (digestive enzyme) Immunoglobulin (antibodies) Insulin (hormone) Red blood cells
Gene
DNA that codes for certain traits (e.g. TCHH gene codes for trichohyalin in hair)
Allele
Variant of the gene
Genotype
Type of relevant genes for a trait (could involve multiple genes and alleles)
Phenotype
Trait that is expressed
How are chromosomes inherited in sexual reproduction?
23 pairs of chromosomes (46 total)
Inherit one chromosome from each pair from each parent
Composition of chromosomes
22 pairs + 1 sexual pair
Sex chromosomes: XX female, XY male
Inheritance of sex chromosomes
Y chromosome inheritance is always from father to son
Mitochondria inheritance always from mother to her children
Types of traits (5)
Adaptive (increases fitness) Neutral (no effect) Maladaptive (decreases fitness) Discrete (attached/detached earlobes) Continuous (height)
Which process is a problem for maintaining variation with sexual reproduction?
Blended inheritance reduces the variability and competition needed for natural selection
Mendelian inheritance
Transmission of hereditary traits in peas (yellow and green, round and wrinkled)
Inheritance works by dominant and recessive traits
This inheritance can be mapped in a punnett square