12: Epigastric Complaint Flashcards
Defensive products/structures in the stomach vs ones that cause GERD
Defensive: LES, UES, peristalsis, saliva, bicarb, mucus
Cause GERD: acid, pepsin, bile acids, trypsin
Possible progression of GERD: five conditions
- GERD
- Reflux esophagitis
- Esophageal stricture
- Barrett’s esophagus
- Esophageal adenocarcinoma
Barrett’s esophagus pathology
Columnar cells of the stomach creep up and replace squamous epithelial cells of the esophagus
Most common complication of PUD
Bleeding
Risk factors associated with poor outcome for PUD bleeding
Age >60, NSAIDs, multi-organ failure, pulmonary complications, malignancy
What causes gastric outlet obstruction
Peri-ulcer edema near the pylorus
First line quadruple treatment for H pylori infection**
- PPI
- Bismuth
- Tetracycline
- Metronidazole
First line clarithromycin triple therapy for H pylori**
- PPI
- Clarithromycin
- Amoxicillin or metronidazole
How does gastric scintigraphy work?
Consume radioactive eggs -> take images of the stomach at 0, 30, 60, and 120 minutes
Metoclopramide MOA
D2 receptor antagonist - stimulates Ach in the GI tract to enhance motility + increase LES tone
Erythromycin: type of Abx
Macrolide
9 Causes of acute pancreatitis
- Gallstones (40% of cases)
- Alcohol (30% of cases)
- Hypertriglyceridemia
- Genetic causes
- Drugs
- Autoimmune causes
- ERCP
- Trauma
- Infection
MRCP stands for?
Magnetic resonance cholangiopancreatography
What is MRCP used for?
Pancreatic ducts, biliary tree
EUS: endoscopic US: functions
- Evaluate biliary tree, panc ducts, panc cysts, masses
2. Can biopsy and perform ERCP