12. Biological and Industrial Applications Flashcards

1
Q

What is a biological ligand?

A

a biomolecule that complexes to a metal ion to serve a biological purpose

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2
Q

What is carbonic anhydrase?

A

the enzyme that catalyses the interconversion of dissolved bicarbonates and carbon dioxide. Found in red blood cells

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3
Q

What is cis-platin?

A

a coordination complex used to treat various types of cancers

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4
Q

What is haemocyanin?

A

a protein containing copper found in molluscs and anthropods that carries oxygen around the body

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5
Q

What is haemoglobin?

A

a protein contain iron found in vertebrates that transports oxygen around the body

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6
Q

What is a metalloprotein?

A

a protein that contains a metal ion cofactor

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7
Q

What is myoglobin?

A

a protein containing iron that carries and stores oxygen in the muscle cells

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8
Q

What is a prosthetic group?

A

a nonprotein group forming part of or combined with a protein

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9
Q

If a prosthetic group contains a metal ion what is it called?

A

Metalloprotein

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10
Q

How many polypeptide chains does myoglobin contain?

A

One

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11
Q

How many polypeptide chains does haemoglobin contain?

A

Four

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12
Q

How is the haem group connected to the Fe ion?

A

It is connected via a histidine nitrogen

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13
Q

Does deoxy-Mb have high-spin or low-spin?

A

High-spin

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14
Q

Does oxy-Mb have high- or low-spin?

A

Low-spin

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15
Q

What state is the oxygen in when it binds to the Fe?

A

Superoxide

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16
Q

What is the active site of haemocyanin made of?

A

Two Cu(I) centers coordinated to three histidine residues each