12 Flashcards

1
Q

presentation primary HIV/ seroconversion

A

abrupt onset

  • flu-like
  • fever
  • malaise
  • lethargy
  • pharyngitis
  • lymphadenopathy
  • toxic exanthoma
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2
Q

management chronic hep B infection

A

to treat if symptomatic without cirrhosis need 2/3 of:

  • > HBV DNA
  • raised ALT
  • significant inflammation/ fibrosis
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3
Q

define septic shock

A

sepsis with persisting hypotension requiring vasopressors requiring vasopressors to maintain MAP >65mmHg
+
serum lactate >2mmol/l despite adequate volume resus

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4
Q

describe linezolid as an antibiotic in staph aureus infection

A
  • bacteriostatic
  • synthetic oxazolidinone
  • good penetration into bone
  • excellent bioavailability
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5
Q

describe pseudomembranous colitis

A

swelling or inflammation of the large intestine due to c.diff overgrowth

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6
Q

what is the malaria vector

A

female anopheles mosquito

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7
Q

presentation of neuroborreliosis

A

triad:

  • facial nerve palsy
  • radicular pain
  • lymphocytic meningitis

onset of symptoms 2-6 weeks after bite

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8
Q

potential complications of malaria

A
  1. cerebral malaria
  2. blackwater fever
  3. pulmonary oedema
  4. jaundice
  5. severe anaemia
  6. gram negative septicaemia
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9
Q

presentation acute acrodermatitis chronica atroficans

A

affects extensor surfaces of distal extremities

bluish-red discolouration

peripheral neuropathy

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10
Q

cause of erythema migrans

A

Lyme disease

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11
Q

precautions that should be taken with c.diff patient

A
  • wash hands with soap and water
  • isolation
  • PPE
  • clean environment
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12
Q

management c.diff infection if no severity markers

A
  • stop unnecessary antibiotics
  • rehydrate

oral metronidazole

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13
Q

management c.diff infection if >2 severity markers

A
  • stop unnecessary antibiotics
  • rehydrate

oral vancomycin

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14
Q

management lyme borrelios

A
  • oral doxycycline/ amoxicillin
  • IV ceftriaxone
  • treat for 21 days
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15
Q

management leptospirosis

A
  • doxycycline for mild disease
  • IV penicillin for severe
  • prompt dialysis
  • mechanical ventilation
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16
Q

where would you find clostridium pefringens

A

undercooked meat/ cooked foods left out

17
Q

when do HEV symptoms occur

A

more than 40 days incubation

18
Q

define sepsis

A

life threatening organ dysfunction caused by dysregulated host response to infection

19
Q

sepsis ‘take 3’

A
  • blood cultures
  • blood lactate
  • urine output
20
Q

management large areas of impetigo

A

topical and oral antibiotics e.g. flucloxacillin

21
Q

presentation impetigo

A

multiple vesicular lesions on an erythematous base

golden crust is highly suggestive of this diagnosis

22
Q

PJP investigations

A
  • CD4 count
  • FBC
  • CXR
  • induced sputum or bronchoscopy for PCR