11.Science2-60T Flashcards

1
Q
  1. IT AND COMPUTER

5. 1. BIG DATA

A

Why in news?
• Big data is being increasingly used by the
government in policy formation.
What is Big Data?
• Big data is a term that describes the large
volume of data – both structured and
unstructured beyond the ability of commonly
used software tools to capture, curate,
manage, and process data within a tolerable
elapsed time.
• Big data can be analyzed for insights that lead
to better decisions and strategic business
moves.
• Big data is characterized by 4Vs – Variety,
Volume Velocity and Value. Additionally, two
more concepts have been added – Variability
and Complexity
• Interesting insights from big data can be got
using data mining.
Applications of Big Data
• Better understanding and targeting of
customers.
• Optimization of Businesses processes
• optimizing treatment and even predicting
diseases
• Analyze and improve the performance of
individuals
• Prevent cyber-attacks, detect credit card
fraud, foil terrorism and even predict criminal
activity.
• optimizing the heating or lighting in our
homes, the traffic flow in our cities, or the
energy grid across the country.
In the wake of challenges for Big data in India,
government had constituted a committee under Justice B.N. Srikrishna which came out with a
white paper on Data Protection Framework for
India. Earlier in 2016, CAG finalized a Big Data
Management Policy to make itself future ready.

Data mining
• It’s defined as a process used to extract usable
data from a larger set of any raw data by
analysing data patterns in large batches of data
using one or more software
• It involves effective data collection and
warehousing as well as computer processing.
• It uses sophisticated mathematical algorithms for
segmenting the data and evaluating the
probability of future events.
• Data mining is also known as Knowledge
Discovery in Data (KDD).

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2
Q

5.2. MAHARASHTRA’S PUBLIC

CLOUD POLICY

A

Why in News?
Maharashtra became the first state to mandate
its departments to shift their data storage onto
the cloud unlike currently where government
departments have their own data storage
facilities.
Details
• Cloud Storage- Cloud storage is a service
model in which data is maintained, managed,
backed up remotely and made available to
users over a network or cloud services
platform (typically the Internet).
• Apart from storage, cloud computing also
involves on-demand delivery of compute
power, applications, and other IT resources
Similar Government initiatives
• Digilocker Service- It is a part of goverment’s
Digital India Initiative, to enable Indian
citizens to store certain official documents on
the cloud.
• GI Cloud Initiative (Meghraj): To accelerate
delivery of e-services in the country while
optimizing ICT spending of the Government.
The National Informatics Centre (NIC) is
providing National Cloud services under this.

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3
Q

5.3. BLOCK-CHAIN

TECHNOLOGY

A

Why in news?
The Finance Ministry recently issued a statement
warning against investing in bitcoin and other
cryptocurrencies (CCs). These currencies use a
technology called blockchain.

What are cryptocurrencies?
• A cryptocurrency is a digital or virtual currency
that uses cryptography for security. Hence it is
difficult to counterfeit. It is not issued by any
central authority, rendering it theoretically
immune to government interference or
manipulation.
The first cryptocurrency to capture the public
imagination was Bitcoin, which was launched in
2009 by an individual or group known under the
pseudonym Satoshi Nakamoto. Bitcoin’s success
has spawned a number of competing
cryptocurrencies, such as Litecoin, Ethereum,
Namecoin, PPCoin etc.
• Advantages: easier to transfer funds with minimal
processing fees, safety from hackers due to blockchain
technology and difficult to counterfaeit
• Disadvantages: well-suited for illegal activities
such as money laundering, tax evasion due to
anonymous nature of transactions, rate of
exchange of cryptocurrencies fluctuate widely and
a digital cryptocurrency balance can be wiped out
by a computer crash. Recently concerns are being
raised on its immunity to hacks as well.
• Various countries have adopted use of bitcoins
with regulations such as China, South Korea,
Japan etc.
• Some countries are also coming up with their
virtual currencies such as PETRO by Venezuela,
SOV (Sovereign) by Marshall Islands etc.
• India does not consider crypto-currencies as legal
tender or coin.

What is it?
• Blockchains are basically digital ledgers or
decentralized database of financial
transactions that are immutable and instantly
updated across the world.
• Distributed database: The blockchain
database isn’t stored in any single location,
meaning the records it keeps are truly public
and easily verifiable.
• Whenever a financial transaction happens, it
is grouped in a cryptographically protected
block with other transactions and sent out to
the entire network.
• The members in the network then validate
the transactions by solving complex coded
problems.
• The new validated block is then added to the
chain in a linear, chronological order and
linked to older blocks making it a chain of
blocks that show every transaction made in
the history of that blockchain
• Thus, the blockchain cannot be controlled by
a single entity and has no single point of
failure
Importance
• The World Economic Forum in 2015, predicts
that 10% of global GDP will be stored on the
blockchain by 2027.
• Crypto currency (CC) is just one use of
Blockchain technology. The other possible
uses are – streamlining payment mechanism,
eliminated the need for trust. Programmable
money to not allow using products of
company flouting norms, promoting artificial
intelligence and internet of things etc.
Challenges:
The main challenges today are the missing
standards, the unclear legal and regulatory
framework, lacking confidence and technical
issues. Current blockchains have trouble with
scalability and latency (i.e. verification speed).

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4
Q

5.4. INDIA JOINS QUANTUM

COMPUTING RACE

A

Why in news?
Department of Science and Technology is
planning to fund a project to develop quantum
computers.
What is quantum computing?
• In a classical computer, information is stored
using binary units, or bits. A bit is either a 0 or
1. A quantum computer instead takes
advantage of quantum mechanical properties
to process information using quantum bits,
or qubits.
• They function according to two key principles
of quantum physics: superposition and
entanglement.
• Superposition means that each qubit can
represent both a 1 and a 0 at the same time.
• Entanglement means that qubits in a
superposition can be correlated with each
other; that is, the state of one (whether it is a
1 or a 0) can depend on the state of another.
• Using these two principles, qubits can act as
more sophisticated switches, enabling
quantum computers to function in ways that
allow them to solve difficult problems that
are intractable using today’s computers.
• The computing power of a quantum
computer increases exponentially as the
qubits are increased.
• It can be used in research in new medicine
and organic materials as quantum computers
would require 3.5 million fewer steps as
compared to a traditional machine.
• Other uses – efficient logistics and delivery
mechanism, more secure platforms for
banking transactions, revolutionize artificial intelligence by faster processing of
complicated data, faster communication etc.
Quantum mechanics (QM): QM deals with sub-atomic
particles viz electrons and photons. It is used in
making products such as integrated circuit chips and
fibre-optic lines for global, instantaneous
communication.
Quantum cryptography: It is a recent technique that
can be used to ensure the confidentiality of
information transmitted between two parties by
exploiting the counterintuitive behavior of elementary
particles such as photons. Quantum cryptography is
different from traditional cryptographic systems in
that it relies more on physics, rather than
mathematics, as a key aspect of its security model.
QUESS
• China launched the world’s first satellite under
the Quantum Experiments at Space Scale
(QUESS) mission, to test the fundamentals of
quantum communication in space.
• It is known as Micius, after an ancient Chinese
philosopher

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5
Q

5.5. SUPERCOMPUTERS

PRATYUSH AND MIHIR

A

Why in news?
Recently, the Minister for Earth Sciences (MoES)
unveiled India’s fastest supercomputer named
Pratyush and high performance computer system
‘Mihir’.

More on news
• MoES has acquired a high performance
computing (HPC) system which is an array of
computers jointly hosted by IITM, Pune and
National Centre for Medium Range
Weather Forecasting, Noida.
• The HPC at Pune is named Pratyush with a
capacity of 4 petaflops (a measure of a
computer’s processing speed expressed as a
quadrillion floating point operations per
second) and HPC at Noida named Mihir with
capacity of 2.8 petaflops giving a total
capacity of 6.8 petaflops.
• It is India’s first multi-petaflop
supercomputer and is the fourth fastest
super-computer in the world which is
dedicated to weather and climate research
after Japan, U.S.A. and United Kingdom.
• It will also take India up from the present
365th position to top 30 in the
infrastructural ranking of Top 500 HPC
facilities in the world.
• Other top five super computers of India are
SahasraT (Cray XC40), Aaditya (IBM/Lenovo
system), TIFR Colour Boson (Cray XC-30), IIT
Delhi HPC and Param Yuva 2.
• Sunway TaihuLight is the World’s fastest
computer, belonging to China

National Supercomputing Mission
• It’s implemented and steered jointly by the
Department of Science and Technology (DST) and
Department of Electronics and Information
Technology (DeitY)
• Mission envisages empowering our national
academic and R&D institutions spread over the
country by installing a vast supercomputing grid
comprising of more than 70 high-performance
computing facilities.
• These supercomputers will also be networked on
the National Supercomputing grid over the
National Knowledge Network (NKN) under
Ministry of Electronics & Information Technology.
• The NKN is another programme of the
government which connects academic institutions
and R&D labs over a high speed network
• The Mission also includes development of highly
professional High Performance Computing (HPC)
aware human resource for meeting challenges of
development of these applications.

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6
Q

5.6. PANEL FOR AI ROADMAP

A

Why in news?
• The government has formed a high-level
panel under the chairmanship of Rajiv Kumar
to lay out a roadmap for India’s research and
development on AI and its applications.
Other Developments
• Recently, Department of Defence Production
constituted a task force headed by N
Chandrasekaran, to study use of artificial
intelligence in military.
41
• Commerce and Industry Minister Sets up Task
Force chaired by V. Kamakoti on Artificial
Intelligence for Economic Transformation.

Artificial Intelligence
• It is branch of computer science dealing with
simulation of intelligent behavior in computers visa-
vis visual perception, speech recognition,
decision making and translation between
languages.
• It enables computer system to carry out task on
their own that otherwise requires human
intelligence.
• Robotics is also a major field related to AI.

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7
Q

5.6.1. PROJECT BRAINWAVE

A

• Microsoft has launched “Project Brainwave”,
a deep learning acceleration platform for
real-time artificial intelligence (AI).
• It uses the massive field-programmable gate
array (FPGA) infrastructure.
• The system architecture allows very high
throughput, with the FPGA processing
requests as fast as the network can stream
them.
• Significance: Real-time AI is becoming
increasingly important as cloud
infrastructures process live data streams,
whether they be search queries, videos,
sensor streams, or interactions with users.
About deep learning
• It is a subset of machine learning which
utilizes hierarchical level of artificial neural
networks to process unstructured data.
• Neural networks are a set of algorithms,
modeled loosely after the human brain, that
are designed to recognize patterns
• A hierarchical neural network is an
artificial neural network(ANN) with multiple
hidden layers between the input and output
layers

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8
Q

5.6.2. HUMANOID

A

• A humanoid robot is a robot with its overall
appearance based on that of the human
body.
• Features of Humanoid Robots
o Self-maintenance
o Autonomous learning
o Avoiding harmful situations to people,
property, and itself
o Safe interacting with human beings and
the environment
• Androids are humanoid robots built to
resemble a male human, and Gynoids are
humanoid robots built to resemble a human
female.
• Recently, Humanoid Robot Sophia became
world’s first robot citizen as Saudi Arabia
granted citizenship to her in a bid to promote
artificial intelligence.
• Other Example: Unplugged (USA), Asimo
(Japan), Icub (Cognitive Universal Body by
European university), Poppy (france), Lexy &
Tess (Germany), Actroid-Sit (Japan) etc.

About Sophia
• Sophia is a social humanoid robot developed by
Hong Kong-based company Hanson Robotics
under David Hanson.
• Sophia is conceptually similar to the computer
program ELIZA, which was one of the first
attempts at simulating a human conversation.
• The software has been programmed to give prewritten
responses to specific questions .The
information is shared in a cloud network which
allows input and responses to be analysed with
blockchain technology.
• She also made surprise appearance at UN and also
joined meeting on artificial intelligence and
sustainable development.
In Artificial intelligence, turing test is a method of
inquiry for determining whether or not a
computer is capable of thinking like a human
being.

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9
Q
    1. TELECOM SECTOR

5. 7.1. BHARAT NET PROJECT

A

Why in news?
As of now, over 1.04 lakh gram panchayats have
been made “service ready” for providing
broadband connectivity as on March 11 under
Bharat Net project

Bharat Net Project
• In 2011, National Optical Fibre Network
(now called Bharat Net Project) was
launched to provide broadband connectivity
to 2.5 lakh Gram Panchayats with an
affordable broadband connectivity of 2 Mbps
to 20 Mbps.
• It is being implemented by a special purpose
vehicle (SPV) named Bharat Broadband
Network Ltd (BBNL) set up under Companies
Act.
42
• It is funded through Universal Service
Obligation Fund (USOF)
• Bharat Net Project is also significant for
generation of as much as 5 lakh jobs during
the installation of Wi-Fi hot spots.
• Some issues involved are high usage of
internet through mobile phone, cyber
security, high cost of services, low internet
education.

About International Telecommunications Union
• ITU is the United Nations specialized agency for
information and communication technologies –
ICTs.
• It allocates global radio spectrum and satellite
orbits, develop the technical standards that
ensure networks and technologies seamlessly
interconnect, and strive to improve access to ICTs
to underserved communities worldwide.
• Members: It includes both public and private
sector membership i.e 193 UN Member States
and ICT regulators, many leading academic
institutions and some 700 tech companies.

Universal Service Obligation Fund:
• It aims to provide non-discriminatory access to
quality ICT services at affordable prices to people
in rural and remote areas through subsidy support
to incentivizing telecom service providers to
venture forth and provide services to such target
beneficiaries.
• It was envisaged in National Telecom Policy, 1999
and was given statutory status through Indian
Telegraph (Amendment) Act, 2003.
• The resources are raised through a ‘Universal
Access Levy (UAL)’, which would be a percentage
of the revenue earned by the operators under
various licenses.
Optical Fibre Technology
• Fibre optics, is the science of transmitting data,
voice, and images by the passage of light through
thin, transparent fibres.
• Optical fibre is made up of semiconducting
materials and usually has a cylindrical structure. In
inner core there is material of higher refractive
index than in outer core resulting in Total Internal
Reflection (TIR)
• When light passes from a medium with one index
of refraction (m1) to another medium with a
lower index of refraction (m2), it bends or
refracts away from an imaginary line
perpendicular to the surface (normal line)
• However at critical angle, the refracted light
travel along the surface between the two media
and at angle greater than critical angle, the
refracted beam will be reflected entirely back into
m1. This phenomenon is known as total internal
reflection.
• Optical fibers allow data signals to propagate
through them by ensuring that the light signal
enters the fiber at an angle greater than the
critical angle of the interface between two types
of glass.

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10
Q

5.7.2. 5G

A

Why in news?
• The government has set up a high level forum
to evaluate roadmaps and formulate a
strategy to adopt 5G in the country by 2020.
What is 5G?
• 5G is a wireless communication technology. It
is the next generation mobile networks
technology after 4G LTE networks.
• The final standard for 5G will be set up by the
International Telecommunications Union
(ITU).
What is spectrum and how does it work?
• Spectrum refers to the radiowaves that are
used by mobile phones to transmit data.
• The spectrum has been divided into bands by
the government for uninterrupted
transmission of data.
• Carriers in India use airwaves in the 800 Mhz,
900 Mhz, 1800 Mhz, 2100 Mhz, 2300 Mhz
and 2500 Mhz bands.
Low-frequency transmissions can travel greater
distances before losing their integrity, and they
can pass through dense objects more easily. Less
data can be transmitted over these radio waves.
43
Higher-frequency transmissions carry more data,
but are poorer at penetrating obstacles. The
higher the frequency, the lower the wavelength,
and thus the more energy that’s required to
cover the same distance.

Generation Year
1 generation
(1G)
• First wireless communication.
• Voice Calls.
• Limited capacity, not secure,
background interference
• 2 Kbps
2 Generation
(2G)
• Digital version of 1G technology
• Voice calls, Short messages,
browsing (partial)
• Low network range, slow data
rates
• 64 Kbps
3 Generation
(3G)
• Digital broadband, speed
increments
• Video conferencing, mobile TV,
GPS
• High power consumption, Low
network coverage, High cost of
spectrum licence.
• 2 Mbps
4 Generation
(4G)
• Very high speeds, All IP
• High speed applications, mobile
TV, Wearable devices
• Hard to implement, complicated
hardware required
• 1 Gbps
5 Generation
(5G)
• Cell densification, software
defined network, low signal
traffic
• Hologram TV, Augemented
reality, Ultra large and high data
transfer, energy saving.
• More than 1 Gbps

Wireless Planning and Coordination (WPC) Wing,
under Department of Telecommunications (DoT) is
responsible for spectrum management at the national
level.
About The internet of things (IoT)
• The internet of things (IoT) is the network of
physical devices, vehicles, buildings and other
items-embedded with electronics, software,
sensors, and network connectivity that enable
these objects to collect and exchange data.
• Thus IoT creates opportunities for more direct
integration of the physical world into computerbased
systems, and resulting in improved
efficiency, accuracy and economic benefits
• IoT is one of the platforms of today’s Smart City,
and Smart Energy Management Systems. It can
also be used to improve crop yield to help feed
the world’s growing population.
About Array of Things (AoT):
• It’s an urban sensing project, a network of
interactive, modular sensor boxes that will be
installed around city to collect real-time data on
the city’s environment, infrastructure, and activity
for research and public use.
• It is expected to provide localised information to
the authorities enabling them to act quickly in
emergencies and warn citizens of environmental
threats.
VoLTE (Voice over Long Term Evolution)
• It is an Internet Protocol Multimedia Subsystem
(IMS) specification which enables a variety of
services to operate seamlessly on the network
rather than having to switch to different
applications for voice or video.
• Volte offer high definition (HD) quality voice calls,
lesser call drops and calls get connected
significantly faster, in comparison with standard
voice calls over 3G and 2G networks.

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11
Q

5.7.3. FREE SPACE OPTICAL

COMMUNICATION

A

Why in news?
• X Development LLC, a subsidiary of Google’s
parent company Alphabet will supply and
deploy two thousand cutting-edge Free
Space Optical Communication (FSOC) links
for Andhra Pradesh (AP) fiber-grid.
• AP Fibre Grid project is aimed to establish a
highly scalable network infrastructure,
accessible on a nondiscriminatory basis, to
provide on demand, affordable and end-toend
broadband connectivity for all
households, institutions & Offices. It is being
implemented by Andhra Pradesh State
Fibernet Limited
What is Free Space Optical Communication?
• It is an optical communication technology in
which data is transmitted by propagation of
light in free space allowing optical
connectivity.
• Working of FSO is similar to OFC (optical fiber
cable) networks but the only difference is
that the optical beams are sent through free
air or vaccum instead of glass fiber.
• It is a Line of Sight (LOS) technology. It
consists of an optical transceiver at both ends
to provide full duplex (bidirectional)
capability.
• It is capable of sending up to 1.25 Gbps of
data, voice, and video communications
simultaneously through the air.
• Advantages: low initial investment, flexible
network that delivers better speed than
broadband, security due to line of sight
operation etc.
• Challenges: misalignment errors, geometric
losses, background noise, weather
attenuation losses and atmospheric
turbulence.

X is a research and development facility founded by
Google in January 2010.
It has been working on several projects including
driver-less car, product delivery through flying
vehicles, Project Loon, Google glass among other
technologies.

• It is a high speed wireless communications
through light emitting diodes (LEDs).
• It uses both visible and near-visible light for freespace
communication.
• LiFi is not strictly a line-of-sight technology i.e.
data rate is not dependent on the line of sight but
on the signal quality at the device.
Parameters Light Fidelity Wireless Fidelity
Speed for
data
transfer
>1 Gbps Upto 15 Mbps
Carrier Light as a carrier Use Radio
spectrum
Cost Cheaper than WiFi Expensive due to
radio spectrum
44
Operating
Frequency
Hundred to Tera Hz 2.4 GHz
Coverage About 10 metre About 32 metre
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12
Q

5.7.4. RFID

A

Why in news?
Recently National Highways Authority of India
launched two mobile apps MyFASTag and
FASTag Partner to facilitate Electronic Toll
Collection. FASTag is a device which uses RFID
technology for making toll-payment directly from
the prepaid account.
About RFID
• Radio-Frequency Identification (RFID) is the
use of radio waves to read and capture
information stored on a tag attached to an
object. A tag can be read from up to several
feet away and does not need to be within
direct line-of-sight of the reader to be
tracked. It is applied for tracking items or as a
pass.
Other related technologies
• Near Field Communication (NFC) is a shortrange
high frequency wireless
communication technology that enables the
exchange of data between devices over
about a 10 cm distance. It is used in credit
card related payments, e-booking etc.
• Barcode scanner detects the light reflected
from the barcode. This needs to be kept in
range of several inches to several feet to read
the code.
• QR code (Quick Response code)
o It’s a two-dimensional (matrix) machinereadable
bar code made up of black and
white square. This code can be read by
the camera of a smartphone.
o It carries information both horizontally
and vertically. It has error correction
capability and data stored in it can be
restored even if it is partially damaged or
dirty.
o It is capable of 360 degrees (omnidirectional),
high speed reading.
o QR Code can store up to 7089 digits as
compared to conventional bar codes
which can store max 20 digits.
• Bluetooth technology
o It is a high speed low powered wireless
technology which uses radio waves to
link phones, computers and other
network devices over short distance
without wires.
o Wireless signals transmitted with
Bluetooth cover short distances, typically
up to 30 feet (10 meters).
o Bluetooth sends and receives radio waves
in a band (frequency band of 2.45GHz ) of
79 different frequencies and can connect
up to “eight devices” simultaneously
o It overcomes the constraints of line of
sight and one to one communication as in
other mode of wireless communications
like infrared.
o It guarantees security at bit level. When a
group of two or more Bluetooth devices
are sharing information together, they
form a kind of ad-hoc, mini computer
network called a piconet.
o It removes the problem of radio
interference by using a technique called
Speed Frequency Hopping. This ensures
that the interference won’t take place as
each transmitter will be on different
frequencies.

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13
Q

5.7.5. TARANG SANCHAR PORTAL

A

Why in News?
• The Telecom Department launched a portal –
Tarang Sanchar Portal that will allow people
to track radiation emitted from mobile
towers within a locality.
• The portal will empower consumers to know
about the towers working in a particular area
and whether they are compliant to the
Electromagnetic field (EMF) emission norms
defined by the government.
• In general, mobile tower emissions rules in
India are ten times more stringent than the
global norms
About radiation
Energy emitted from a source is generally
referred to as radiation. There are two types of
radiation:
• Ionizing radiation is radiation with enough
energy to cause chemical changes by
breaking chemical bonds. This ionization
process results in the formation of two
charged particles or ions: the molecule with a
net positive charge, and the free electron
with a negative charge. This effect can cause
damage to living tissue.
45
o Examples include heat or light from the
sun, microwaves from an oven, X rays
from an X-ray tube, and gamma rays from
radioactive elements
• Non-ionizing radiation is the term given to
radiation in the part of the electromagnetic
spectrum where there is insufficient energy
to cause ionization but may have enough
energy to excite molecules and atoms causing
then to vibrate faster.
o Example: It includes electric and
magnetic fields, radio waves,
microwaves, infrared, ultraviolet, and
visible radiation.
Application of Radiation
• Medical Application: X-Ray, CT, and PET
machines use X-ray (X-ray and CT) and
Gamma radiation (PET) to produce detailed
images of the human body,
• Industrial Application: to examine welds for
defects or irregularities, or examining other
materials to locate structural anomalies or
internal components.
• Food irradiation is the process of using
radioactive sources to sterilize foodstuffs.
• As a disinfectant: Ultraviolet light is used to
disinfect drinking water in some homes.
• Pollution Abatement: Radiation is used to
help remove toxic pollutants, such as exhaust
gases from coal-fired power stations and
industry. For

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14
Q

5.7.6. TRAI FAVOURS NET

NEUTRALITY

A

Why in news?
• Recently, Telecom Regulatory Authority of
India (TRAI) has favoured net neutrality.
• Also, Washington has become first state
recently to enact its own net-neutrality rules
Background
• The debate on net neutrality in India started
from Facebook launching Free Basics and
Airtel launching Airtel Zero.
• These were opposed by IT industry body
Nasscom as it violated net neutrality
principles by differentiating internet access
for certain types of services.
Recommendation
• Non-Discriminatory treatment: irrespective
of sender, receiver protocols used etc.
• Specialised Service: are exempted from
neutrality framework such as tele-surgery,
Voice over Internet Protocol (VoIP) and IPTV
services etc.
• Content delivery Network (CDN) platform:
should not be included within the scope of
any restrictions on non-discriminatory
treatment
• Reasonable traffic Management practices:
by framing appropriate regulations time to
time.
• Regulatory Body: TRAI suggested DoT may
establish a multi-stakeholder body with
framework for collaborative mechanism
among the stakeholders for monitoring the
net-neutrality.

Net Neutrality
• Net Neutrality or Network neutrality is the idea
that Internet service providers (ISPs) should treat
all data that travels over their networks fairly,
without improper discrimination in favour of
particular apps, sites or services.

VoIP
Voice over Internet Protocol (VoIP), is a technology
that allows you to make voice calls using a broadband
Internet connection instead of a regular (or analog)
phone line.
CDN platform
CDN is a system of servers, deployed at the edge of (or
within) the terminating network of an access provider,
that content provider can use to distribute their
content

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15
Q

5.8. NATION-WIDE
HACKATHON
#OPENGOVDATAHACK
LAUNCHED

A

Why in news?
Recently, Ministry for Electronics & Information
Technology launched nation-wide hackathon
#OpenGovDataHack with an aim to support and
showcase great ideas or talent and enable them
to develop apps or infographics by use of Open
Government Data.
Background
• #OpenGovDataHack is an on-site 24Hrs
Challenge which will be held at 7 centres. The
participating teams will be required to submit
the App prototype and info-graphics, out of
46
these selected apps will be taken up for
further development and the winner will be
awarded. The theme of the Hackathon was
“Drinking Water & Sanitation, Transport,
Education, Crime and Health”.
Open Government Data (OGD) Platform
• OGD has been set up by the National
Informatics Centre (NIC) in accordance with
National Data Sharing and Accessibility
Policy (NDSAP) 2012.
• It is a platform which provides
o single point access to open data sets, it
also provides web based workflows to
departments so that they can publish
their datasets through a predefined
metadata.
o better visualization tools, better user
experience and efficient discoverability of
resources.
o Community participation through blogs,
info-graphics, visualizations, mobile and
web apps etc.
• OGD platform is currently being
supplemented by various sectors such as
health and family welfare, home affairs,
agriculture, rajya sabha, statistics and
programme etc.

National Data Sharing and Access Policy, 2012
• The Policy aims to provide an enabling provision
and platform for providing proactive and open
access to the data generated through public funds
available with various departments of
Government.
• The policy also facilitates the access to
Government shareable data readable and
machine readable form though an all India
network within the framework of various policies,
acts and rules.
• The principle of data sharing and accessibility is
based on openness, flexibility, transparency,
quality, security and machine-readability.

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16
Q
    1. CYBER ISSUES

5. 9.1. NIC-CERT

A

Why in news?
Government inaugurated the new body National
Information Centre-Computer Emergency
Response Team (NIC-CERT) to prevent and
predict cyber-attacks on government utilities.
Background
• In May 2017, a ransomware called
Wannacry, infected more than 100,000
computers all over the world.
• Indian Computer Emergency Response Team
(CERT-In) in June, 2017 issued an advisory
about Petya or Petrwrap, in the series of
ransomware attacks affecting computer
systems across the world whose spreading
mechanism were similar to attack such as
EternalBlue, Psexec, Windows Management
Instrumentation.
Effect on India
Government steps to tackle cybercrime
Setting up NIC-CERT
• NIC-CERT is a dedicated body to detect,
prevent and mitigate the impact of cyberattacks,
by monitoring data across the NIC
platform, including communication between
all the levels of government and between
governments to citizens.
• It will help in real time data monitoring and
operate in close coordination and
collaboration with sectoral CERTs and CERTIN.
• Securing Digital India Initiative: NIC-CERT will
help in securing digital initiative of
government by preventing the threats and
vulnerabilities arising due to cyberspace.

About National Information Centre
• It comes under Ministry of Electronics and IT
(MeitY) and has a key role in e-governance at the
national, state and district levels. Almost all
Indian-government websites are developed and
managed by NIC.

• Malware: Malware is short for malicious
software, meaning software that can be used to
compromise computer functions, steal data,
bypass access controls, or otherwise cause harm
to the host computer. Malware is a broad term
that refers to a variety of malicious programs.
• Bot: Bots are software programs created to
automatically perform specific operations. While
some bots are created for relatively harmless
purposes (video gaming, internet auctions, online
contests, etc), it is becoming increasingly common
to see bots being used maliciously.
• Ransomware: It is a form of malware that
essentially holds a computer system captive while
demanding a ransom. The malware restricts user
access to the computer either by encrypting files
on the hard drive or locking down the system and
47
displaying messages that are intended to force
the user to pay the malware creator to remove
the restrictions and regain access to their
computer.
• Spyware: Spyware is a type of malware that
functions by spying on user activity without their
knowledge. Spyware spreads by exploiting
software vulnerabilities, bundling itself with
legitimate software, or in Trojans.
• Trojan Horse: A Trojan horse, is a type of malware
that disguises itself as a normal file or program to
trick users into downloading and installing
malware. A Trojan can give a malicious party
remote access to an infected computer.
• Virus: A virus is a form of malware that is capable
of copying itself and spreading to other
computers. Viruses can be used to steal
information, harm host computers and networks,
create botnets, steal money, render
advertisements, and more.
• Worm: Computer worms are among the most
common types of malware. They spread over
computer networks by exploiting operating
system vulnerabilities. Worms typically cause
harm to their host networks by consuming
bandwidth and overloading web servers. Worms
often spread by sending mass emails with infected
attachments to users’ contacts.
Two recent initiatives
Cyber Surakshit Bharat Initiative
• It has been launched by Ministry of Electronics
and Information Technology (MeitY), in
association with National e-Governance Division
(NeGD) and industry partners, to strengthen
Cybersecurity ecosystem in India.
• It is first public-private partnership of its kind and
will leverage the expertise of the IT industry in
cybersecurity.
• The founding partners include leading IT
companies such as Microsoft, Intel, WIPRO. Its
knowledge partners include Cert-In, NIC,
NASSCOM and consultancy firms Deloitte and EY.
• It will be operated on three principles of
Awareness, Education and Enablement.
• It aims to spread awareness about cybercrime and
build capacity of Chief Information Security
Officers (CISOs) and frontline IT staff across all
government departments.
Global Centre For Cybersecurity
• It has been launched by the World Economic
Forum (WEF) with headquarter in Geneva.
• It will function as an autonomous organization
under WEF. It will serve as laboratory and earlywarning
think tank for future cybersecurity
scenarios and help to build a safe and secure
global cyberspace.
• Its aim is to establish first global platform for
governments, businesses, experts and law
enforcement agencies to collaborate on
cybersecurity challenges and work towards an
appropriate and agile regulatory framework on
cybersecurity.
Global Conference on Cyber Space (GCCS)
• Theme: “Cyber4All: A Secure and Inclusive
Cyberspace for Sustainable Development”.
• Aim: to establish internationally agreed ‘rules of
the road’ for behavior in cyberspace, and create a
more focused and inclusive dialogue between all
those with a stake in the internet on how to
implement them.
• It has set up an institutional mechanism – Global
Forum on Cyber Expertise – to enhance capacity
building, share best practices and expertise on
cyber capacity.

Section 69B of IT Act, 2000, talks about the power to
authorize to monitor and collect traffic data or
information through any computer resource for Cyber
Security.

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17
Q

5.9.2. BUDAPEST CONVENTION

A

Why in news?
Ministry of home affairs recently called for
signing of the Budapest Convention on
cybercrime owing to the surge in cyber-crime.

Steps taken by Government
• Information Technology Act, 2000(amended
in 2008) provides a legal framework for
transactions carried out by means of
electronic data interchange and other means
of electronic communication.
• Indian Computer Emergency Response Team
(CERT-in): established to enhance the
security of India’s Communications and
48
Information Infrastructure through proactive
action and effective collaboration. CERT-fin
has also been launched exclusively for
financial sector.
• National Cyber Security Policy 2013:
proposes to set up different bodies to tackle
various levels of threats, along with a
national nodal agency, to coordinate all
matters related to cyber security.
• National Critical Information Infrastructure
Protection Centre (NCIIPC) to battle cyber
security threats in strategic areas such as air
control, nuclear and space. It will function
under the National Technical Research
Organisation (NTRO)
• National cyber coordination centre (NCCC) is
being set up to scan internet traffic coming
into the country and provide real time
situational awareness and alert various
security agencies.
• Indian cyber-crime coordination centre (I4C)
and Cyber Warrior Police force has been
established under newly created Cyber and
Information Security (CIS) Division (under
Ministry of Home Affairs) to tackle internet
crimes such as cyber threats, child
pornography and online stalking.
• Digital Army Programme: a dedicated cloud
to digitize and automate processes,
procedures and services for the Indian Army,
launched as a part of Digital India. This is
similar to Meghraj, the national cloud
initiative.

About Budapest convention on cybercrime
• This convention of the council of Europe is the
only binding international instrument on this
issue.
• It is the first international treaty on crimes
committed via the Internet and other computer
networks and deals with issues such as
infringements of copyright, computer-related
fraud, child pornography and violations of
network security.
• It aims to pursue a common criminal policy,
especially by adopting appropriate legislation and
fostering international police as well as judicial cooperation.
• It provides for procedural law tools to make
investigation of cybercrime and securing of eevidence
in relation to any crime more effective
• The Convention has 56 members, including the US
and the UK.

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18
Q

5.9.3. DIGITAL POLICE PORTAL

UNDER CCTNS

A

Why in news?
Recently Home Minister launched a digital police
portal under the CCTNS project.
More on news
• CCTNS has originally aimed at maintenance of
crime and criminal records of individuals
through a national database, and delivery of
web based police related services to all
citizens.
• Digital Police portal is a SMART policing
initiative of government with aim to provide
Services to Citizens at a National level
o Report a Crime
o Request for person verification
o Links to State Citizen Portal
• The access has been restricted only to
authorized officials to protect Privacy of
individual and concerns of National security.
• The portal also generates various thematic
reports of trends of incidence of crime
across the country to facilitate policy analysis
and undertaking targeted interventions.

Crime and Criminal Tracking Network and Systems
(CCTNS)
It is a project of MHA launched in 2009 which aims to:
• Provide Citizen Centric Police Services via a web
portal.
• Pan India search on National database of Crime &
Criminal records.
• Crime and Criminal reports at State and Centre.
• Computerization of Police Processes.
Inter-operable Criminal Justice System (ICJS)
• It is a component of CCTNS
• ICJS aims to integrate the CCTNS project with the
e-courts and e-prisons databases initially and
later to all components of criminal justice system

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19
Q

5.9.4. CYBER-SECURITY INDEX

A

Why in news?
• India is ranked a high 23rd out of 165 nations
in The Global Cybersecurity Index (GCI).
Background
• The second Global Cybersecurity Index (GCI),
released by the International
Telecommunication Union (ITU), said only
about half of all countries have a
cybersecurity strategy or are in the process of
developing one
• The top 3 most committed countries to
cybersecurity are Singapore United States
and Malaysia.
• India has been listed in the “maturing”
category, which refers to 77 countries that
have developed complex commitments to
cybersecurity and engage in cybersecurity
programmes and initiatives.

About ITU
• ITU, based in Geneva, Switzerland, is the leading
UN agency for ICT.
• As the global focal point for governments and the
private sector, ITU’s role in helping the world
communicate spans 3 core sectors: radio
communication, standardization and
development.
ITU also organizes TELECOM events and was the lead
organizing agency of the World Summit on the
Information Society

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20
Q

5.10. WORLD CONGRESS ON
INFORMATION TECHNOLOGY
(WCIT)

A

Why in news?
Recently World Congress on Information
Technology (WCIT) 2018 or the ‘Olympics of IT’
was held in Hyderabad for the first time in India.
More about the news
• The theme of this edition of conference was
‘Future Enterprises.’
• WCIT is a biennial event and considered as
the biggest event of its kind. It aims to
provide single platform to IT experts, policy
and decision makers and Government
officials from all over the world together to
discuss various challenges and and possible
solutions to them.
• It is unique in its global perspective on ICT
issues and its ability to draw users, providers,
media and academia from around the world.
• It was first held in 1978 since then held after
every two years. The 2014 WITC 2016 edition
was held in Brasilia, Brazil.

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21
Q
  1. HEALTH

6. 1. VECTOR BORNE DISEASES

A

Define: Vector-borne diseases are human
illnesses caused by parasites, viruses and bacteria
that are transmitted by mosquitoes, sandflies,
blackflies, ticks, tsetse flies, mites, snails and lice
etc.
Example: Diseases such as malaria, dengue,
Visceral leishmaniasis, kala-azar/ Dumdum
Fever), yellow fever, Japanese encephalitis,
Chikungunya, Zika etc.
National Vector Borne Disease Control Programme
(NVBDCP)
• It is an umbrella programme for prevention and
control of vector borne diseases and is subsumed
under National Health Mission.
• Directorate of NVBDCP is the central nodal agency
for the prevention and control of vector borne
diseases
• Vector borne diseases that are being targeted:
Malaria, Dengue, Lymphatic Filariasis, Kala Azar,
Japanese Encephalitis, chikungunya
Directorate of National Vector Borne Diseases
Control Programme
• It’is the central nodal agency for the prevention
and control of vector borne diseases i.e. Malaria,
Dengue, Lymphatic Filariasis, Kala-azar, Japanese
Encephalitis and Chikungunya in India
• It is under the aegis of Union Ministry of Health
and Family Welfare.
• Function: National level Technical Nodal office for
framing technical guidelines & policies as to guide
the states for implementation of Programme
strategies.

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22
Q

6.1.1. INDIA AND ZIKA VIRUS

A

Why in news?
Recently the United States sent out an advisory
informing its citizens in India about the number
of confirmed Zika infections in India.
Background
• The WHO has placed India as a ‘Category-2’
country for Zika risk.
• A Category-2, the second highest on a fourpoint
scale and that also includes 2015 Zikahotspot
Brazil, indicates that the virus is
being actively transmitted within the country.
• Until April, India was a Category-4 country.
About zika virus
• Zika virus disease is caused by a virus transmitted
primarily by Aedes mosquitoes. Aedes aegypti is
a known vector of several other viruses
including yellow fever virus, dengue virus and
chikungunya virus.
• Zika can be passed through sex from a person
with Zika to his or her partners.
• People with Zika virus disease can have symptoms
including mild fever, skin rash, conjunctivitis,
muscle and joint pain, malaise or headache. These
symptoms normally last for 2-7 days.
• There is scientific consensus that Zika virus is a
cause of microcephaly and Guillain-Barré
syndrome.
• An additional area of concern is the difference
between Zika on the one hand and dengue or
chikungunya on the other. While the latter
conditions occur soon after a mosquito bite, the
presence of the Zika virus will be known six
months later, after the birth of microcephalic
infants.
• US scientists have developed a plant-based Zika
vaccine that could be more potent, safer and
cheaper to produce than other medicines being
developed for the disease.
• It is developed using tobacco plant and targets a
key protein called DIII, which envelopes the
outside of the Zika virus and plays a key role for
the virus to infect people.

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23
Q

6.1.2. MONKEY FEVER

A

Why in news?
Scientists have traced the source of a reemerging
disease, Kyasanur Forest Disease
(KFD) or “monkey fever”, to cashew plantations
in Goa.
What is monkey fever?
• It is caused by Kyasanur forest disease virus
(KFDV), a member of the virus family
Flaviviridae, which also causes yellow fever
and dengue.
• It was first detected in 1957 in Shimoga,
Karnataka and is endemic to South Asia.
51
• Monkey fever is so named because it
primarily affects black-faced langurs and redfaced
bonnet monkeys and result in death.
Even when the monkey dies still the KFD virus
gets transmitted through ticks thriving on
monkeys.
• The Hard ticks (Hemaphysalis spinigera) are
the reservoir of KFDV. These ticks are known
to thrive in the Western Ghats and transmit
the disease to humans

Monkey Fever Symptoms
• High fever with headache, followed by
haemorrhagic symptoms such as bleeding from
the nose, throat and gums
• Gastrointestinal bleeding,
• Muscle stiffness, tremors, absent reflexes and
• Mental disturbances.

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24
Q

6.1.3. ELEPHANTIASIS

A

Why in news?
Recently, it was speculated that Government will
miss out the set deadline to eliminate
Elephantiasis.
Elephantiasis or Lymphatic Filariasis
• It is a parasitic disease caused by the
parasitic worms called filial worms which is
spread by the bite of the infected black flies
and mosquitoes.
• The disease parasite is usually acquired
during childhood. The larvae in the human
can live in human beings for up-to 5-8 years
without showing any symptoms; however the
lymphatic system is damaged.
• Elephantiasis leads to severe swelling in
arms, legs, knees and genitals causes
disfigurement and disability.
Burden of Disease
• India alone accounts for 40% of world’s
disease burden with over 31 million
microfilaraemics, 23 million cases of
symptomatic filariasis, and about 500 million
individuals at risk of contracting the disease.
• India had set the ambitious target to
eradicate the disease by 2020 which was
earlier set at 2015 under the National Health
Policy 2002.
Efforts to eradicate the Disease in India
• In 1995, government launched National
Filaria Control Program
• In India, since 2004, Mass Drug
Administration (MDA) is being carried on as a
part of the Hathipaon Mukt Bharat (Filaria
Free India) programme for preventive
medication.

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6.1.4. KALA AZAR
Why in news? India has missed the deadline (December 2017) of eliminating Kala Azar (Visceral leishmaniasis or Black fever or Dum Dum fever). Background • In 2017 budget speech, the Finance Minister had announced for elimination (reducing to less than one case in 10,000) of Kala Azar by 2017. It was also reiterated by the National health policy 2017. • In 2014, the government launched the Kala Azar Elimination Programme with support from various international agencies. • However, endemic blocks have increased from 61 to 68 in 17 districts of Bihar and Jharkhand. Ancient remedy for Kala Azar • Scientists from Indian Institute of Chemical Biology in Kolkata tested ancient remedy described in Charaka Samhita to fight drugresistant kala-azar. • The compound called mahanine was isolated from leaves of curry plant commonly used in Indian kitchens has been found to inhibit the growth of kala-azar parasite.
26
6.1.5. JAPANESE ENCEPHALITIS (JE)
Why in news In August 2017, around 30 children affected by JE admitted at Gorakhpur's BRD Medical College had died over shortage of oxygen supply. Encephalitis: It is a non-communicable disease that results in inflammation of the brain. The patient's central nervous system is affected. It can be caused due to bacterial or viral infections of the brain, injection of toxic substances or increased complications of an infectious disease. • It’s transmitted by the infective bite of the Culex species of mosquitoes • It belong to the same genus as dengue, yellow and West Nile viruses • Japanese Encephalitis is covered under Universal Immunisation Programme (UIP). Acute Encephalitis Syndrome (AES) including Japanese Encephalitis (JE) is a group of clinically similar neurologic manifestation caused by several different viruses, bacteria, fungus, parasites, spirochetes, chemical/ toxins etc o It is characterized by an acute onset of fever and clinical neurological manifestation that includes mental confusion, disorientation, delirium, or coma. JENVAC: It’s first indigenous vaccine to protect children from Japanese encephalitis. It’s also the first vaccine to be manufactured in the publicprivate partnership mode between the Indian Council of Medical Research and Bharat Biotech
27
6.2. NEGLECTED TROPICAL | DISEASES
Why in news WHO (World Health Organisation) in it's report on neglected tropical disease (NTD) applauded the progress made on elimination of NTD. What are Neglected Tropical Diseases • WHO defines NTDs as a diverse group of communicable diseases that prevail in tropical and subtropical conditions in 149 countries. • Vulnerability: Populations living in poverty, without adequate sanitation and in close contact with infectious vectors and domestic animals and livestock are those worst affected. • Situation in India: Diseases that are most prevalent in India include lymphatic filariasis, soil transmitted helminthiases, trachoma, visceral leishmaniasis, dengue, rabies, cysticercosis, Japanese encephalitis and intestinal worm infections (hookworms, whipworms and Ascaris worms). National Programmes in relation to tropical diseases are being implemented: • National Vector Borne Disease Control Programme (NVBDCP): For control of Dengue and elimination of Kala-azar and Lymphatic Filariasis. • National Leprosy Eradication Programme: India has achieved the elimination of leprosy at national level in December 2005. Focus is now to achieve elimination of leprosy at district level. • National Programme for Control of Blindness: Services are provided for the control of Trachoma. • School Health Programme: services are provided for the prevention of Soiltransmitted Helminthiases. • National Deworming Day (February 10): Children between ages 1 to 19 through schools and anganwadi centres were dewormed in order to improve their nutritional status and well-being • WASH strategy: It’s a critical component of prevention and care for all NTDs. Provision of safe water, sanitation and hygiene is one of the five key interventions in the global NTD road map. • WHO NTD roadmap: It outlined bold targets for the control, elimination or eradication of 17 NTDs by 2020 • Uniting to Combat NTDs: Leaders of several prominent global health and development organizations, together with industry partners, met in London in 2012 and pledged to unite in their efforts to support the achievement of the WHO 2020 goals in respect to 10 NTDs. o Pledge is known as London Declaration on NTDs o 10 NTDs are: Guinea worm disease, lymphatic filariasis, blinding trachoma, sleeping sickness, leprosy, helminthes, schistosomiasis, river blindness, Chagas disease and visceral leishmaniasis (Kala Azar).
28
6.2.1. NATIONAL DEWORMING | MISSION
Why in news? Recently government celebrated the National Deworming Day. About National Deworming Day • It was started in 2015 as a part of the National Health Mission, implemented in 11 States/UTs across all Government and Government-aided schools and Anganwadi centres. • It entails single fixed day approach to treat intestinal worms in all the children from 1 to 19 years on February 10 and August 10 each year. • Along with administering Albendazole tablets, some other activities are also performed such as behaviour change practices, cleanliness and hygiene guide, use of toilets, wearing shoes or slipper, washing hands before eating food and after using toilet, etc. in order to reduce the incidents of re-infection. Soil Transmitted Helminth (STH) infection • It is caused by different species of parasitic worms which can live and replicate in the gastrointestinal system. • The STHs (hookworms, roundworms, whipworms) are transmitted by eggs present in human faeces, which contaminate the soil in areas where sanitation is poor. • Infected children are nutritionally and physically impaired. While deworming has been shown to reduce absenteeism in schools; improve health, nutritional, and learning outcomes; and increase the likelihood of higher-wage jobs later in life.
29
6.3. POLIO VACCINE
Why in news? • The World Health Organization has declared Gabon a "polio-free country", given the lack of new reported or suspected cases in the central African country. • Now the disease is endemic only in Afghanistan and Pakistan, where the WHO recorded four cases this year—two in each country. Polio: A fact sheet • Polio (or Poliomyelitis) is a highly-infectious viral disease which mainly affects young children and can result in permanent paralysis. • The virus is transmitted by person-to-person spread mainly through the faecal-oral route or, less frequently, by a common vehicle (e.g. contaminated water or food) and multiplies in the intestine, from where it can invade the nervous system and can cause paralysis. • There is no cure and it can only be prevented through immunisation. • Types: Of the 3 strains of wild poliovirus (type 1, type 2, and type 3), wild poliovirus type 2 was eradicated in 1999 and no case of wild poliovirus type 3 has been found since 2012. • Difference between Oral Polio Vaccine (OPV) and IPV: OPV is made up of attenuated or weakened poliovirus and there is a risk of vaccine derived polio. IPV is made up of inactivated (killed) polio virus and will provide immunity from all three strains of polio. • India status: India was officially decalred Polio free by WHO in 2014. • However, samples from some states showed the presence of Type 2 vaccine derived polio virus (VDVP), which had undergone ten nucleotide changes. • If six or more nucleotide changes happen then it is called vaccine-derived poliovirus (VDVP). • VDVP is extremely rare and found in children with immune-deficiency and among populations with low immunity levels.
30
6.4. MOTHER-TO-CHILD | TRANSMISSION OF HIV
What is it: HIV transmitted from a HIV positive mother to her child during pregnancy, delivery or breast feeding is called mother-to-child transmission (MTCT). Mother-to-child-transmission • Intervention in MTCT cases usually involves – o Antiretroviral treatment for the mother and a short course of antiretroviral drug for the baby. o Counselling and psychological support to help mothers safeguard their children against the infections. • Steps being taken in India: o Earlier in India, ‘Single dose therapy’ was being practised wherein the ART was administered 72 hrs before birth. However, in 2014 WHO recommended ‘multidrug therapy’ was adopted. o Multidrug Therapy is a combination of three drugs — Tenofovir, Lamivudine And Efavirenz (TLE) which the infected mother is required to take throughout their lives except nevirapine which is supposed to be taken by new born only for six weeks. o In 2002, Prevention of Parent to Child Transmission of HIV/AIDS (PPTCT) program was launched. National Aids Control Organisation (NACO) It is an organisation which was set up under Ministry of Health and Family Welfare for formulation of policies and implementation of programs for prevention and control of HIV/AIDS. Child Friendly HIV Drug • Recently, Central Drugs Standard Control Organisation (CDSCO) has registered the childfriendly and heat-stable oral pellet formulation of the HIV drug lopinavir/ritonavir (LPV/r). • Significance: The lack of child-friendly HIV formulations is a major reason for a large treatment gap between adults and children. Due to this gap paediatric HIV is considered neglected disease. The registration of the pellets is a positive sign as the needs of children are being addressed. About CDSCO • It is the national regulatory body for Indian 54 pharmaceuticals and medical devices under Ministry of Health and Family Welfare. • Major functions include: Regulatory control over the import of drugs, approval of new drugs and clinical trials, meetings of Drugs Consultative Committee (DCC) and Drugs Technical Advisory Board (DTAB), approval of certain licences as Central Licence About HIV • The Human Immunodeficiency Virus targets the immune system and weakens people's defence systems against infections and some types of cancer making infected individuals immunodeficient gradually. • The most advanced stage of HIV infection is Acquired Immunodeficiency Syndrome (AIDS), which can take from 2 to 15 years to develop depending on the individual. AIDS is defined by the development of certain cancers, infections, or other severe clinical manifestations. • It can be transmitted via the exchange of a variety of body fluids from infected individuals, such as blood, breast milk, semen and vaginal secretions. • Individuals cannot become infected through ordinary day-to-day contact such as hugging, shaking hands, or sharing personal objects, food or water.
31
6.5. NOROVIRUS AT WINTER | OLYMPICS
Why in news? At the Winter Olympics in Pyeongchang, South Korea, there have been many cases of infection with Norovirus. Details • Norovirus is a very contagious virus. It’s a common cause of gastroenteritis, or inflammation of the intestine. • It spreads from an infected person mainly by direct contact (such as shaking hands), by touching an infected surface or though contaminated water and food.
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6.6. BIRD FLU
Why in news? • India has declared itself free from Bird Flu (highly pathogenic Avian Influenza - H5N1 and H5N8) and notified it to the World Organisation for Animal Health. • The move will help it resume export of poultry products to the countries which had banned trade in such items early this year. Avian Influenza • There are 3 types of influenza viruses: types A, B, and C. Influenza A viruses infect humans and many different animals • Influenza type A viruses are classified into subtypes according to the combinations of different virus surface proteins Haemagglutinin (H) and Neuraminidase (N). • Influenza A viruses can be classified as avian influenza, swine influenza, or other types of animal influenza viruses • Examples include avian influenza "bird flu" virus subtypes such as A (H5N1) and A(H9N2). World organization for Animal Health • It is recognised as a reference organisation by the World Trade Organization (WTO) and in 2017 has a total of 181 Member Countries. • It maintains permanent relations with 71 other international and regional organisations. • Ban is lifted after 90 days of the surveillance is done by the organization.
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6.7. H1N1 VIRUS (SWINE FLU)
Why in news? • Government removed antiviral drugsoseltamivir and zanavir - from schedule X category allowing all pharmacies to sell and stock these drugs. • These drugs were earlier restricted as their misuse and overuse can lead to drug resistance. About H1N1 Virus • It is a contagious respiratory disease caused by Type A strains of the Swine Influenza virus. • It enters body through inhalation of droplets or is transferred from a contaminated surface to eyes, nose or mouth and can spread from human to human. • It is called swine flu because in the past, the people who caught it had direct contact with pigs. • Drugs and Cosmetics Rules, 1945: Any sale of medicine in the country is regulated under this act. • Drugs specified in Schedules H, H1 and X cannot be sold except on, and in accordance with the prescription of a Registered Medical Practitioner from a licensed premises.
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6.8. TUBERCULOSIS
Why in News? • A joint study conducted by Foundation for Innovative New Diagnostics (FIND) and Revised National TB Control Programme (RNTCP), has found that the Multi-Drug Resistant (MDR) TB is higher among children than expected. Paediatric TB • Paediatric MDR-TB cases had not been documented so far. • Children are more prone to primary MDR –TB infection as they are in close contact with infected person. • TB diagnosis in children is complicated due to challenges associated with sample collection and poor sensitivity of tests like the Acid fast bacilli (AFB) smear. • Thus, the foundation FIND started rolling out GeneXpert to diagnose TB • Government had issued a specific guideline for paediatric TB under Revised National TB Control Program (RNTCP). • RNTCP aims at diagnosing and treating TB throughout the country. It uses DOTS (Directly Observed Treatment Short course) and DOTS-plus strategy (where there are significant cases of MDR-TB) Recently, Moscow Declaration was also adopted in WHO Global Ministerial Conference on Ending Tuberculosis with an aim towards achieving SDG Goal 3.3.2 to end epidemic of TB incidence per 1000 population. Drug Resistant TB MDR-TB • It is TB that does not respond to at least isoniazid and rifampicin (2 of the most powerful first line drugs) • It is developed due to o Inappropriate or incorrect use of antimicrobial drugs, o Use of ineffective formulations of drugs (such as use of single drugs, poor quality medicines or bad storage conditions) o Premature treatment interruption. • Recently, Ministry of Health has approved Delamanid drug in order to combat the increasing burden of MDR-TB. • Delamanid will be inducted parallel to Bedaquiline under Revised National Tuberculosis Control Program (RNTCP) and not replace it XDR-TB • It is resistant to at least four of the core anti-TB drugs such as levofloxacin or moxifloxacin, amikacin, capreomycin or kanamycin.) • Developed due to same mechanism as MDR-TB. TDR-TB or XXDR-TB • TB which is resistant to all the first and second line TB drugs. • This makes it almost but not totally impossible to treat. GeneXpert MTB/RIF Test • It detects the presence of TB bacteria (Mycobacterium tuberculosis), as well as tests for resistance and genetic mutation to the drug Rifampicin
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6.9. HOME GROWN VACCINE FOR LEPROSY: MYCOBACTERIUM INDICUS PRANII
``` Why in News? • National Institute of Immunology has developed Mycobacterium Indicus Pranii (MIP), an indigenous vaccine for leprosy. Highlights • India has been declared Leprosy free country in 2005 because of less than one case per 10,000 population. • MIP is now being introduced into the National Leprosy Elimination Programme (NLEP). It will boost the immune system against the bacterial disease. ``` What is Leprosy? • Bacterial disease caused by Mycobacterium leprae, • Affects the skin and peripheral nerves. • Long incubation period generally 5-7 years. • Timely diagnosis and treatment of cases, before nerve damage has occurred, is the most effective way of preventing disability.
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6.10. INTENSIFIED DIARRHOEA | CONTROL FORTNIGHT
Why in news? • The Ministry of Health and Family Welfare has launched the Intensified Diarrhea Control Fortnight (IDCF) in order to reduce child deaths due to diarrhea. Background • WHO estimated diarrhea is second leading cause of death under five year age of children worldwide. • Despite of consistent decline in Infant Mortality Rate (IMR) and Under-Five Mortality Rate (U5MR) there has been 1 lakh deaths due to diarrhoea in India. Intensified Diarrhea Control Fortnight (IDCF) • ASHA worker would undertake distribution of ORS packets to households with under-five children in her village. • ORS-Zinc Corners will be set-up at health care facilities and non-health facilities such as Schools and Anganwadi centres. • Apart from oral medicine Health ministry introduced Rotavirus vaccine under UIP will also help in reducing diarrhoea mortality. What is Diarrhea? • Can be causes by virus, bacteria and parasite. • Diarrhea is having frequent, loose stools which causes dehydration • Can be spread from affected person, contaminated food or drinking contaminated water. • Can be prevented with safe drinking water, sanitation, breastfeeding/appropriate nutrition and hand-washing. What is ORS (Oral Rehydration Salt Solution)? • ORS is a glucose-electrolyte solution containing salt and sugar water. • It can be simple, cheap and effective for all age groups. • Supplemented with Zinc tablet, the duo is called ORS Jodi. National Oral Rehydration Therapy (ORT) Program in 1985-86 • Improving maternal knowledge related to the use of home available fluids. • Ensuring availability of ORS packets at health facilities. • Integrated part of Child Survival and Safe Motherhood (CSSM) Program.
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6.11. FIRST INDIA-DESIGNED | VACCINE PASSED WHO TEST
Why in news? Recently, India made ROTAVAC vaccine and Typbar Typhoid Conjugate Vaccine received WHO pre-qualification. ROTAVAC Vacccine • It is a low cost vaccine developed by Bharat Biotech Limited under an innovative PPP model involving Ministry of Science and Technology, institutions of the US Government and various NGOs. • It has been included in India’s Universal Immunization Program in 2016. Typbar Typhoid Conjugate Vaccine • It is the world’s first typhoid vaccine, developed by Bharat Biotech limited that can be given to infants older than six months. It and confers long-term protection against typhoid fever. 57 Significance of Pre-Qualification • Accelerate availability of the vaccine to the developing countries with highest burden of diseases • Increases the scope for credible industrial, scientific and regulatory processes to develop more vaccines in the country. • Necessary for United Nation agencies like UNICEF, the Pan American Health Organization (PAHO) and GAVI (a vaccine alliance) to purchase the vaccine in partnership with developing countries. Rotavirus • It is the most common cause of diarrhoea among infants and young children. • It usually transmitted by the faecal-oral route and infects and damages the cells in the small intestines and causes gastroenteritis. Typhoid • It is caused by the bacteria Salmonella typhi. • The infection is often passed on through contaminated food and drinking water, and it is more prevalent in places where hand washing is less frequent.
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6.12. NEW DEVELOPMENTS IN NON-COMMUNICABLE DISEASES
According to India State Level Disease Burden Report, over the past 26 years the pattern of diseases has shifted from communicable, maternal, neonatal, and nutritional diseases (CMNNDs) to non-communicable diseases (NCDs) and injuries
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``` 6.12.1. INDIA HYPERTENSION MANAGEMENT INITIATIVE (IHMI) ```
Why in news? Ministry of Heath and Family Welfare (MoHFW) and Indian Council of Medical Research (ICMR) launched IHMI. More about IHMI • Aim: To reduce disability and death related to cardiovascular disease (CVD), by improving the control of high blood pressure (hypertension), reducing salt consumption and eliminating artificial trans-fats, leading risk factors for CVD. • This initiative will strengthen the cardiovascular disease component of the Health Ministry’s National Program for Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke (NPCDCS) and is aligned with WHO’s Global HEARTS Initiative and National Guidelines.
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6.12.2. JEEVAN BINDI
Why in news? A Singapore based marketing agency and Maharashtra based NGO developed a Vermillion (Bindi) named Jeevan-Bindi which contains iodine. Jeevan Bindi • It is medically enhanced version of regular bindi, embedded with iodine along with the adhesive base. • Bindi delivers the daily requirement of iodine 100-150 adsorption through the skin. • It needs to be worn every day for up to eight hour to be effective. • This initiative is supplemented with iodine pills available at community health centre. • The initiative focus pregnant women because the effects of iodine deficiency are most severe in them and reflected in new-born. Iodine • It is a trace mineral and a nutrient found naturally in the body and can be easily fortified with salt. • Humans need iodine for the production of thyroid hormones. • It needed for the cells to convert food into energy. • Deficiency leads to goiter, hyperthyroidism, stunted growth or intellectual disabilities. • Source: seafood, daily products, and other protein food. National Iodine Deficiency Disorders Control Programme 1992 • It aims at bring the prevalence of IDD( to below 5% in the country • It ensures 100% consumption of adequately iodated salt (15ppm) at the household level. • Iodate the entire edible salt in the country.
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6.12.3. THALASSEMIA
Why in News? • On World Thalassemia day (May 8) various researchers and health experts called for National Policy on Thalassemia. 58 What is Thalassemia? • It is a genetic blood disorder with no cure except bone marrow transplant (BMT). • Characterised by abnormal production of haemoglobin in the body. The abnormality results in improper oxygen transport and destruction of red blood cells. • Lead to iron overload, bone deformities and in severe cases can cause heart diseases. • It requires regular blood transfusions as an effective measure to prolong life. • Thalassaemia is now considered as a disability under Rights of Persons with Disabilities Act 2016, rather than a health issue
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6.13. ANTIBIOTIC RESISTANCE: WHO REVISES ANTIBIOTICS PROTOCOL
Why in news? WHO has revised antibiotics protocol to curb antibiotic resistance. This is the biggest revision of the antibiotics section in the essential medicines list (EML). Details WHO has divided the drugs into three categories: access, watch and reserve. • The ‘access’ category includes commonly used antibiotics. They will be available at all times as treatment for a wide range of common infections. • The ‘watch’ group covers antibiotics that are recommended as first or second choice treatment for a small number of infections. Prescription of these drugs should be reduced to avoid further development of resistance. • The ‘reserve’ category includes antibiotics that are considered last-resort options and used only in the most severe circumstances such as for life-threatening infections due to multidrug-resistant bacteria. Recently, Ministry of Science and Technology have released the Scoping Report on Antimicrobial Resistance in India. Highlights of the report • In 2014, India was the highest consumer of antibiotics, followed by China and the United States. However, the per capita consumption of antibiotics in India is much lower than in several other high income countries. • India has some of the highest antibiotic resistance rates among bacteria that commonly cause infections in the community and healthcare facilities. • It has also pointed that the resistance to carbapenem class of antibiotics (one of the last-resort antibiotics to treat serious bacterial infections in humans) among various bacteria was extremely high. • Antibiotic-resistant bacterial infections are also increasingly reported among neonates. Factors responsible for antibiotic resistance in India • Self-medication (to avoid financial burden) • Access to antibiotics without prescription • Use of pharmacies and informal healthcare providers as sources of healthcare. • Inadequate public sector diagnostic laboratory and Unaffordability of private labs • Mass bathing as part of religious occasions • Antibiotics as growth promoters in food animals and poultry • Effluents from the antibiotic manufacturing units leading to contamination of rivers and lakes • Disposal of untreated sewage into water bodies • Prevalence of various Healthcare Associated Infections (HAI). Policy/Initiatives of Government • National Policy for Containment of AMR 2011 provided regulations for use of antibiotics for humans as also for veterinary use along with a hospital based surveillance system for monitoring antibiotic resistance. • Indian Council of Medical Research (ICMR) has set up a National Anti-Microbial Resistance Research and Surveillance Network (AMRRSN) to enable compilation of National Data of AMR at different levels of Health Care. • FSSAI has set certain guidelines limiting the antibiotics in food products such as fish and honey. • Recently, Ministry Of Health has notified an amendment to the Food Safety & Standards (Contaminants, Toxins & Residues) Regulations, 2011, to set maximum permissible limits for the presence of antibiotics and other drugs in meat and meat products, including chicken. • Red Line Campaign on Antibiotics 2016, was launched to create awareness regarding rational usage and limiting the practice of self-medication of antibiotics among the general public. • National Health Policy 2017 envisions a holistic framework against AMR. • The National Action Plan on Antimicrobial Resistance (NAP-AMR) 2017 has assigned coordinated tasks to multiple government agencies involving health, education, environment, and livestock to change prescription practices and consumer behaviour and to scale up infection control and antimicrobial surveillance. o The strategic objectives of NAP-AMR are aligned with the WHO’s Global Action Plan on AMR (GAP-AMR). It occurs when microorganisms such as bacteria, viruses, fungi and parasites change in ways that render the medications used to cure the infections and causing them ineffective. • It is the broader term for resistance in different types of microorganisms and encompasses resistance to antibacterial, antiviral, antiparasitic and antifungal drugs. • It occurs naturally but is also facilitated by the inappropriate use of medicines. • Microorganisms that become resistant to most antimicrobials are often referred to as “superbugs”. • It affects the, medical procedures such as organ transplantation, cancer chemotherapy, major surgeries etc. making them very risky. WHO (World Health Organization) • It is a specialised agency of UN concerned with international public health. • It was established on 7 April 1948, headquartered in Geneva, Switzerland. • The WHO publishes World Health Report. WHO “Global action plan on antimicrobial resistance” 2015: it has 5 strategic objectives: • To improve awareness and understanding of antimicrobial resistance. • To strengthen surveillance and research. • To reduce the incidence of infection. • To optimize the use of antimicrobial medicines. • To ensure sustainable investment in countering antimicrobial resistance. Other International Initiatives • ‘One Health’ approach: to designing and implementing programmes, policies, legislation and research in which multiple sectors communicate and work together to achieve better public health outcomes against the food safety, the control of zoonoses (diseases that can spread between animals and humans, such as flu, rabies), antimicrobial resistance etc. • World Antibiotic Awareness Week. • The Global Antimicrobial Resistance Surveillance System. • Interagency Coordination Group on Antimicrobial Resistance. • Essential medicines are the medicines that "satisfy the priority health care needs of the population". • These are the medications to which people should have access at all times in sufficient amounts. The prices should be at generally affordable levels. • The WHO publishes Model List of Essential Medicines (EML) every two years since 1977. It is used by countries to develop their own local lists of essential medicine. Hospital Acquired Infections (HAI) • Also called nosocomial infections, HAI are passed onto the patients after being admitted at the hospital facility. • International Nosocomial Infection Control Consortium is an international scientific organisation that works to fight against healthcare associated infections. Implications • Creates additional suffering for patients and comes at a high cost for their families. • It increases hospital stays and creates long-term disability • Increases resistance to antimicrobials • Increases cost burden for healthcare systems and causes unnecessary deaths. Causes of HAI • Lack of proper Equipment, Understaffing and Overcrowding, Lack of knowledge of injection and blood transfusion safety, Prolonged and inappropriate use of invasive devices and antibiotics etc. Recently, a Bengaluru firm received the international CARB-X grant to develop antibiotics to treat HAI. CARB-X a public-private international partnership to address the gap in antibiotic R&D and to improve diagnosis & treatment of drug-resistant infections.
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6.14. PLANT DISEASES
Plant disease is an impairment of the normal state of a plant that interrupts or modifies its vital functions. Types of Plant diseases. • Rust: Fungal disease that attacks roses, hollyhocks, snapdragons, daylilies, beans, tomatoes and lawns. • Wheat blast: Fungal disease that attacks the standing crop. Fungus responsible for the wheat blast disease is known as Magnaporthe oryzae 60 • Pink Bollworm: It is a type of insects attack on cotton which has severely impacted cotton plantations in various parts of the country. • Blight: Blight is easily recognizeable by the suddent death of all plant tissue including leaves, stems and flowers. Blight is typically casued by wet and humid conditions. • Cotton Whitefly: Whiteflies are sucking insects and their feeding removes nutrients from the plant • Chlorosis (discoloration): Chlorosis is when a green tissue turns yellow. It has many causes including pathogens, lack of nutrients, and lack of water. • Leaf Spot: Leaf spots are yellow or brown lesions (often look like burn marks) that takes place on leaves. These are caused by pathogens, fungi, pesticide damage and insect feeding.
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6.15. FORTIFIED FOODS TO | TACKLE MALNUTRITION
Why in news? • Targeting children, Rajasthan, MP, Haryana and Himachal Pradesh governments have begun using fortified oil for their mid-day meal schemes. • West Bengal and A&N Islands are distributing fortified wheat flour through the public distribution system. • Enrichment of food is a process by which nutrients are added. Typically, the added nutrients were present in the food in its original form, but were removed at some point during processing. • Fortification of food is the practice of deliberately increasing the content of an essential micronutrient, i.e. vitamins and minerals (such as iron, iodine, zinc) in a food, so as to improve the nutritional quality of the food supply • Biofortification is the process by which the nutritional quality of food crops is improved through agronomic practices, conventional plant breeding, or modern biotechnology. It aims to increase nutrient levels in crops during plant growth rather than through manual means during processing of the crops. • The Food Safety and Standards Authority of India (FSSAI) released a set of standards and a logo (+F logo) last year for all fortified packaged food.
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6.16. MILK ADULTERATION
Why in news? A recent study on milk samples in Delhi found wide adulteration. Adulteration: Most common harmful adulterants include starch, chlorine, hydrated lime, sodium carbonate, formalin and ammonium sulphate. Milk producers use these to scrimp on milk portions and prepare “synthetic milk” by mixing urea, caustic soda, refined oil and common detergents ``` Common Adulterant Used for Calcium Carbide and Copper Sulphate For ripening of Fruit Colours (Metallic- not permitted) To enhance the appearance of Fruits & vegetable Oxytocin (triggers early puberty among girls, male breast etc.) Induce growth in Vegetable and animals Saccharin Induce sweetness in fruits Parrafin Wax For Shiny appearance of fruits Metanil yelllow For colouring yellow dal Related facts • Neutralizers are substances added to prevent curdling and increase the shelf life of milk. They could be added in the form of caustic soda, sodium bicarbonate and sodium carbonate. ```
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7. PHARMACEUTICALS 7.1. ACTIVE PHARMACEUTICAL INGREDIENTS
Why in News? Department of Pharmaceuticals (DoP) has sought support from other government departments to reduce India’s import dependence on Active Pharmaceutical Ingredients (APIs). More on news • Bulk drugs or APIs are the active raw materials used in a drug that give it the therapeutic effect. • V.M. Katoch committee was formed to formulate a long-term policy and strategy for promoting domestic manufacture of APIs/bulk drugs in India. • Recently, Heavy Water Board has signed an agreement with an Indian firm for supply of Heavy Water for development of deuterium labeled compounds, NMR Solvents, d-labeled Active Pharma Ingredients (APIs). Heavy Water Board (HWB), • It’s a constituent unit of Industries and Minerals Sector under Department of Atomic Energy. • It is primarily responsible for production of Heavy Water (Deuterium Oxide-D2O) which is used as a 'moderator' and 'Coolant' in the nuclear power as well as research reactors. What is Heavy Water? • It is a form of water in which the hydrogen in the molecules is partly or wholly replaced by the isotope deuterium. • Heavy water may be deuterium oxide, D2O or it may be deuterium protium oxide, DHO. • Heavy water occurs naturally, although it is much less common than regular water. • Non-nuclear uses: Preservation of Oral Polio Vaccines, for enhancement of biological efficacy, for enhancing life of lubricants, improving mechanical and chemical properties of polymer etc. Difference with normal water: • High boiling and freezing point • More density • High temperature to achieve maximum density • High pH i.e. more basic in nature
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7.2. PRICE CAP ON KNEE | IMPLANTS
Why in News? • Recently, NPPA capped the prices of knee implants, in a move to reduce product prices by as much as 69%. More on news • The central drug regulator has requested the Union Ministry of Health and Family Welfare to set up a committee to work out ways to bring heart valves, orthopaedic implants and intra ocular (eye) lenses under the National List of Essential Medicines (NLEM). • In response, US firms have approached the United States Trade Representative (USTR) against the price capping with a request to either suspend or withdraw India’s benefits under Generalised System of Preferences (GSP). o GSP is a preferential tariff system extended by developed countries to developing countries involving reduced MFN tariffs or duty free entry of exported products of beneficiary country into the donor country. o MFN status is given by one country to another country with which it is interested in increasing trade. This status gives specific trade advantages such as reduced tariffs. However according to WTO MFN principle, if one country is granted a special favour, the same has to be done for all other WTO members. National List of Essential Medicines (NLEM) • NLEM 2015 contains 376 medicines. • Criteria for inclusion into this list includes public health emergency, cost effective medicine etc. • Core Committee formed by the Ministry of Health, reviews and revises the medicines in the NLEM • Once a drug or medical device is included in NLEM, its price can be capped by NPPA National Pharmaceutical Pricing Authority [NPPA] • It is an independent body under Department of Pharmaceuticals under Ministry of Chemicals and Fertilizers. • Its functions are: o To fix/revise the controlled bulk drugs prices and formulations. o To enforce prices and availability of the medicines under the Drugs (Prices Control) Order, 1995/2013. o To recover amounts overcharged by manufacturers for the controlled drugs from the consumers. o To monitor the prices of decontrolled drugs in order to keep them at reasonable levels.
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7.3. DIGITAL THERAPEUTICS | OR DIGICEUTICALS
Why in news? America’s Food and Drug Administration (FDA) has given its approval to some digital therapeutics. More about Digital therapeutics • It can broadly be defined as a treatment or therapy that utilizes digital and often Internet-based health technologies to spur changes in patient behavior to treat a medical or psychological condition. It uses methods rooted in cognitive behavioral therapy to spur patients to make lifestyle changes. • It is often used as a preventive measure for patients who are at risk of developing more serious conditions. For instance, a patient with prediabetes may be prescribed digital therapeutics as a method to change their diet and behavior. • It can also be used to treat patients with psychological and neurological disorders.
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7.4. USE OF PET BOTTLES FOR | MEDICINES
Why in news? National Institute of Nutrition (NIN) will assess the health impact of the use of polyethylene terephthalate (PET) or plastic bottles to package medicines. About Polyethylene terephthalate (PET) • PET is a strong, stiff synthetic fibre and resin, and a member of the polyester family of polymers. • It is produced by the polymerization of ethylene glycol and terephthalic acid. Applications • It is a major industrial polymer and is used for making disposable beverage bottles, photographic film and magnetic recording tape. • Also made into fibre filling for insulated clothing and for furniture and pillows. • Industrial applications of PET are automobile tire yarns, conveyor belts and drive belts, reinforcement for fire and garden hoses, seat belts, nonwoven fabrics for stabilizing drainage ditches, culverts, and railroad beds, and disposable medical garments. National Institute of Nutrition • The National Institute of Nutrition (NIN), established in 1918 and presently located in Hyderabad, is India’s premier nutrition research institute. It is one of the oldest research centers in India under the Indian Council of Medical Research. • Mission: To enable food and nutrition security conducive to good health, growth & development and increase productivity, so as to achieve the national nutrition goals as per the national nutrition policy. • 2018 marks NIN Centenary (1918-2018) Celebrations. It is organising Conference on “Nutrition Before, Beyond and During First 1000 Days of Life – Evidence to Action”
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7.5. BIOSIMILAR FOR CANCER
Why in news? Recently, Biocon became the first Indian company to get a US Food and Drug Administration (USFDA) nod for a biosimilar drug Ogivri. More from news • Ogivri is a biosimilar to Herceptin, used for treatment of breast cancer or stomach cancer and second for cancer. What are biosimilars? • A biosimilar medicine is a biological medicine that is developed to be highly similar and clinically equivalent to an existing biological medicine. • A biosimilar contains a version of an active substance of an already approved biological medicine, which is referred to as the ‘reference medicine’ or ‘originator medicine’. • They are different from generic medicines, because they contain simpler chemical structures and are identical, in terms of molecular structure, to their reference drugs. 63 • Development of Biosimilars is challenging as it requires high investment and much longer time as compared to generic drug manufacturing. Biological Medicines • Biological medicines are derived from living cells or organisms. • These medicines are proteins, such as hormones or antibodies that the human body produces but in certain diseases, their production shuts down or weakens. • The most important biological medicines are used to treat o Diabetes by substituting for the body’s own insulin production o Various cancers, difficult skin and joint diseases, asthma etc.
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7.6. NATIONAL BIOPHARMA | MISSION
Recently, Innovate in India (i3) i.e. the National Biopharma Mission was launched by the government to make India a hub for design and development of novel, affordable and effective biopharmaceutical products and solutions. About Biopharma mission • Currently India has only 2.8% share in the global biopharmaceutical market, the program would elevate this to 5% resulting in an additional business opportunity of 16 Billion USD. • The Mission to be implemented by Biotechnology Industry Research Assistance Council (BIRAC), a Public Sector Undertaking of Department of Biotechnology, will bring together expertise from national and international corridors to provide strategic guidance and direction to move promising solutions through the product development value chain.
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8. IPR 8.1. INTERNATIONAL INTELLECTUAL PROPERTY INDEX 2018
Why in news? Recently, Global Innovation Policy Centre (GIPC) of US Chambers of Commerce had released the International Intellectual Property Index (IIPI). About the Index • It is an annual Index which examines a country’s Intellectual Property (IP) framework across eight categories of indicators – patents, copyrights, trademarks, trade secrets and market access, enforcement, commercialisation of IP assets, systemic efficiencies and ratification of international treaties. Highlights of the IIPI 2018 • USA topped the list followed by UK and Sweden. • India has been ranked 44 out of 50 countries up from 43 out of 45 in 5th edition. Steps taken by Government to improve the Intellectual Property Rights ecosystem • A comprehensive National IPR policy has been put in place. (please refer to the box) • Integrated approach and synergy had been adopted through transferring various IP offices and Acts under DIPP and also merging Copyrights Board with Intellectual Property Appellate Board. • Cell for IPR Promotion and Management has also been established for assisting in simplifying and streamlining of IP processes as well as creating IPR awareness, commercialization and enforcement. • A Scheme for facilitating Start-up Intellectual Property Protection (SIPP) has been launched for encouraging innovation and creativity of Start-Ups. • India has also become the 90th member of Madrid Protocol. • The Department of Industrial Policy and Promotion (DIPP) has inked agreement with Punjab State Council of Science and Technology to establish India’s first TISC (Technology and Innovation Support Center). o TISC is WIPO’s (World Intellectual Property Organisations) program that provides innovators in developing countries with access to locally based, high quality technology information and related services. o The program will help innovators to fully exploit their creative potential and also protect their Intellectual Property Rights (IPRs). 65 o CIPAM (Cell for IPR Promotion and Management) has been designated as the national focal point for the TISC network. • Scheme for IPR Awareness –Creative India; Innovative India has been launched by CIPAM to raise IPR awareness across India • CIPAM has also launched IPrism, an Intellectual Property Competition for college and university students to foster a culture of innovation and creativity. What is Intellectual Property Rights (IPR)? • Intellectual Property refers to creation of mind such as inventions, literary and artistic works and symbols, names and images used in commerce. • IPR are the rights which allow creators of patents, trademarks or copyrighted work to benefit them for their own work or investment. These rights have been outlined in Article 27 of Universal Declaration of Human Rights. • The importance of IPR was first recognized in the Paris Convention for the protection of Industrial Property (1883) and Berne Convention for the Protection of Literary and Artistic Works (1886) (both administered by WIPO). National Intellectual Rights Policy It is a vision document which aims to create and exploit synergies between all form of intellectual property, concerned statuses and agencies. Main objectives of the policy are – • IPR Awareness and outreach • Stimulate the generation of IPR • Strong legal and legislative framework • Modernize and strengthen service-oriented IPR Administration • Commercialisation of IPR • Enforcement and Adjustment for combating IPR adjustment • Human Capital Development for teaching, training, research and skill building in IPRs. CIPAM, a professional body created under DIPP has been entrusted with the implementation of the National IPR Policy 2016. Madrid Protocol • It is an international treaty that allows a trademark owner to seek registration in any of the countries that have joined Madrid Protocol by filing a single application. • International Bureau of the World Intellectual Property Organisation administers the international registration system. WIPO • WIPO is the global forum for intellectual property services, policy, information and cooperation. • It a specialized a self-funding agency of the United Nations, with 189 member states. • It was established in 1967 and is headquartered in Geneva, Switzerland
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8.2. GEOGRAPHICAL | INDICATION
Why in news? Recently, Geographical Indication (GI) registry granted GI tag to: • Stone sculptures of Mamallapuram • Etikoppaka toys. • Banglar rosogulla (West Bengal). • Gobindobhog rice, a speciality from Burdwan district of West Bengal. • Nilambur Teak: grown in Nilambur region • About the Nilambur Teak o It is also known as Malabar teak and the Mecca of Teak. o It is the first forest produce to get GI tag. o It is known for its durability, earthy colour and larger size. o It exhibits high resistance to fungal decay and shows antioxidant properties making it ideal for usage in construction purposes like Buckingham Palace, the Kabba building in Mecca, the Titanic etc. o It is also known for hydrophobicity and its oily nature. o Teak also has the highest capacity for carbon sequestration among trees in India. About the Gobindobhog rice • A speciality from Burdwan district of West Bengal. • It is cultivated late and therefore not much affected by rains. • It is less prone to pests as well. • The productivity per area is high and farmers get better prices for of this variety. Types of IPR (apart from Geographical Indications) Patent • A patent is granted for an invention which is a new product or process that meets conditions of novelty, non-obviousness and industrial use. • Novelty means inventive step is the feature(s) of the invention that involves technical advance as compared to existing knowledge. • Non-obviousness means the invention is not obvious to a person skilled in the art. • Industrial use means that the invention is capable of being made or used in an industry. • Patents in India are governed by “The patent Act 1970” which was amended in 2005 to make it compliant with TRIPS. Copyright • Copyright is a right given by the law to creators of literary, dramatic, musical and artistic works and producers of cinematograph films and sound recordings. • This right allows its creator the rights of reproduction, communication to the public, adaptation and translation of the work. • Copyrights in India are governed by “The Copyright Act, 1957”. Trademark • It refers to graphical representation of goods or services to make it distinguishable from the others • It can be words, symbols, sound, colours, shape of goods, graphics representation or packaging etc. • They are governed under Trademarks Act, 1999 (amended in 2010) under aegis of DIPP • The ‘fair usage’ of certain trademarks for the purpose of education, research etc. is not available under the Trademarks Act. Therefore the third party is required to seek permission from the owner every time. Design • An industrial design consists of the creation of a shape, configuration or composition of pattern or color, or combination of pattern and color in three-dimensional form containing aesthetic value. • An industrial design can be a two- or threedimensional pattern used to produce a product, industrial commodity or handicraft. • Designs in India are governed by “The Designs Act 2000”. Plant Variety Protection • It refers to the protection granted for plant varieties. These rights are given to the farmers and plant breeders to encourage the development of new varieties of plants. • Plant variety protection in India is governed by “The Protection of Plant Varieties and Farmers’ Rights (PPV&FR) Act, 2001”. NOTE: Stone sculptures of Mamallapuram, and pur Etikoppaka toys are covered in culture booklet GI Tag for other Rice variety in India: • Kalanamak Rice: Uttar Pradesh • Basmati rice: Punjab, Haryana, Himachal Pradesh and Uttarakhand and parts of Uttar Pradesh and Jammu & Kashmir • Ambemohar Rice: Maharashtra • Palakkadan Matta Rice, Navara rice, Pokkali Rice, Wayanad Jeerakasala Rice, Wayanad Gandhakasala Rice, Kaipad Rice: Kerala Other GI product from WEST Bengal Darjeeling Tea, Santiniketan Leather Goods, Laxman Bhog Mango, Fazli Mango, Himsagar (Khirsapati Mango), Santipore Saree, Baluchari Saree, Dhaniakhali Saree, Joynagarer Moa, Bardhman Sitabhog and Bardhman Mihidana. Geographical Indications of Goods (Registration and Protection) Act, 1999 • As a member of the World Trade Organization (WTO), India enacted the Act to comply with the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS). • GI is covered as element of intellectual property rights (IPRs) under Paris Convention for Protection of Industrial Property. • The Act is administered by the Controller General of Patents, Designs and Trade Marks, who is also the Registrar of Geographical Indications. How are GI protected • Sui Generis Systems (i.e. special regimes of protection) • Using Collective Or Certification; and 66 • Methods focusing on business practices, including administrative product approval schemes. What is GI tag? • It is an indication that is definite to a specific geographical territory. It is used for agricultural, natural and manufactured goods having special quality and established reputation. • For a product to get the tag, it needs to be produced or processed or prepared in that region. • The registration of a GI is valid for 10 years after which it needs to be renewed. • GIs support local production and are an important economic tool for the uplift of rural and tribal communities. GI is a collective right. Producers can use the collective GI mark to commercially exploit the products. • Geographical Indicators in India are governed by “The Geographical Indications of Goods (Registration & Protection) Act, 1999”.
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9. ALTERNATIVE ENERGY | 9. 1. SOLAR TECHNOLOGY
Why in news? Recently, world's largest solar park of 2,000 MW, named as 'Shakti Sthala' set up at Pavagada in Tumakuru district, Karnataka. Solar Park scheme • Launched by Ministry of New and renewable Energy (MNRE) and implemented by Solar Energy Corporation (SECI). • Objective: To create at least 50 solar parts with a capacity of 500 MW and above by 2019-20. • Solar Park: It’s a concentrated zone of development of solar power generation projects and provides developers an area that is well constructed, with proper infrastructure, access to amenities and by minimizing paper works for project implementation. Solar technology • Solar energy is the cleanest, most abundant renewable energy source available. • Three primary technologies by which solar energy is commonly harnessed by: o Photovoltaics (PV): It directly convert sunlight to electricity. o Concentrating Solar Power (CSP): It uses heat from the sun (thermal energy) to drive utility-scale, electric turbines. About Solar Cells/Photovoltaic (PV) Cells: PV gets its name from the process of converting light (photons) to electricity (voltage), which is called the PV effect. • How it works: When sunlight strikes the PV module, made of a semiconductor material, electrons are stripped from their atomic bonds. This flow of electrons produces an electric current. Types of solar cell o First Generation solar cells are made from silicon, are usually flat-plate. o Second-generation solar cells are called thin-film solar cells because they are made from amorphous silicon or nonsilicon materials such as cadmium telluride. o Third-generation solar cells: They are made from a variety of new materials besides silicon, including solar inks using conventional printing press technologies, solar dyes, and conductive plastics. Perovskite Solar Cells • What is Perovskite: A perovskite is a material that has the same crystal structure as the mineral calcium titanium oxide (also known as Perovskite). • Perovskite Solar Cell is one that includes a perovskite-structured compound, most commonly a hybrid organic-inorganic lead or tin halide-based material, as the lightharvesting active layer. • Perovskite captures energy from a different part of sunlight’s wavelength than silicon. • Perovskite solar cells in last few years have outpaced all other third-generation solar technologies in terms of efficiency and cost. Solar Energy Corporation of India ltd" (SECI) • It’s a CPSU under the administrative control of the MNRE, • Objective: It’s responsible for implementation of a number of schemes of MNRE, major ones being the VGF schemes for large-scale grid-connected projects under JNNSM, solar park scheme and grid-connected solar rooftop scheme etc • It is the only CPSU dedicated to the solar energy sector. Sunrush: It’s a 25-year period (1992-2017) in which solar power has grown exponentially, transforming the technology from rarefied oddity to the world’s fastestgrowing energy source.
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9.2. INDIA'S THREE-STAGE | NUCLEAR POWER PROGRAMME
It was formulated by Dr. Homi Bhabha in the 1950s to secure the country’s long term energy independence, through the use of uranium and thorium reserves found in the monazite sands of coastal regions of South India. Objective: To utilize the known resources of thorium reserve found in India (India has 25% of world thorium reserves but only 1-2% global uranium reserve), to provide safe and reliable electric power for the country’s social and economic progress and to be self-reliant in all aspects of nuclear technology. ``` STAGE 1: PRESSURISED HEAVY WATER REACTOR • In this natural uranium (0.7 % fissile U-235 and the rest is U-238) fuelled pressurised heavy water reactors (PHWR) which produce electricity while generating plutonium-239 as by-product. STAGE II – FAST BREEDER REACTOR • In the second stage, fast breeder reactors (FBRs) would use a mixed oxide (MOX) fuel made from plutonium-239, recovered by reprocessing spent fuel from the first stage, and natural uranium. • In FBRs, plutonium-239 undergoes fission to produce energy, while the uranium-238 present in the mixed oxide fuel transmutes to additional plutonium-239. • Thus, the Stage II FBRs are designed to "breed" more fuel than they consume. STAGE III – THORIUM BASED REACTORS • A Stage III reactor or an advanced nuclear power system involves a self-sustaining series of thorium-232- uranium-233 fuelled reactors. • This would be a thermal breeder reactor, which in principle can be refueled after its initial fuel charge using only naturally occurring thorium. • According to the three-stage programme, Indian nuclear energy could grow to about 10 GW through PHWRs fueled by domestic uranium, and the growth above that would have to come from FBRs till about 50GW. About Atomic Energy Regulatory Board (AERB) • Atomic Energy Regulatory Board is a statutory body created by the President under Atomic Energy Act, 1962 to carry out the regulatory and safety functions under the Act. • It derives its regulatory powers from the rules and notifications promulgated under the Atomic Energy Act, 1962 and the Environmental (Protection) Act, 1986. BWR PWR PHWR FBR Purpose Electrici ty Electricit y, nuclear powered ships Electricit y, plutoniu m producti on Electricity, plutonium production Coolant Water water Heavy water (D2O) Molten, liquid sodium Moderat or Water water Heavy water (D2O) Not required Fuel Uraniu m dioxide Uranium dioxide (UO2) UO2 or metal Plutonium dioxide and UO2 in different combinatio ns Enrichme nt level Lowenriche d Lowenriched Notenriched Various mixtures of P-239 and U-235 BWR – boiling water reactor // PWR – pressurized water reactor. ```
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9.3. COLD FUSION
Cold Fusion • Cold fusion describes a form of energy generated when hydrogen interacts with various metals like nickel and palladium. Excess heat is generated by the interaction that can be used to turn the turbine. • Cold fusion seeks to produce nuclear energy without harmful radiation, complex equipment and the application of very high temperatures and pressures. • The major challenge is to control the reaction.
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9.4. GRAPHENE BASED | BATTERY
Why in news Recently, Scientists have developed a new graphene-based battery material with charging speed five times faster than lithium-ion batteries. About Graphene • Graphene form of carbon consists of planar sheets (2D structure) which are one atom thick, with the atoms arranged in a hexagonal lattice (honeycomb-shaped lattice). • Very good conductor of electricity and heat • About 200 times stronger than steel and nearly transparent. • Impermeable to gases • Applications: It can be used as/in Paints and coatings, lubricants, oils and functional fluids, capacitors and batteries, thermal management applications, display materials and packaging, solar cells, inks and 3Dprinters’ materials and films etc. 69 Types of Batteries Alkaline batteries • They are non-rechargeable, high energy density, batteries that have a long life span. • Electrolyte used in it is alkaline (non-acidic). • Generally, it has zinc as anode and a carbon rod/manganese dioxide as cathode with potassium hydroxide as the electrolyte. This is similar to dry cell where only electrolyte is different, i.e., ammonium chloride. Non-alkaline batteries: They are similar to alkaline batteries except the electrolyte used is acidic in nature, generally a mixture of ammonium chloride and zinc chloride. • In lead acid battery, the reaction of lead and lead oxide with the sulfuric acid electrolyte produces a voltage Fuel cell • A fuel cell uses the chemical energy of hydrogen or another fuel to cleanly and efficiently produce electricity. If hydrogen is the fuel, electricity, water, and heat are the only products. • Fuel cells work like batteries, but they do not run down or need recharging. They produce electricity and heat as long as fuel is supplied. Fuel-cell vehicles use a completely different propulsion system from conventional vehicles that can be two or three times more efficient • Hydrogen as a pure gas is not easily available. Thus, making it very costly source of energy.
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9.5. LITHIUM-ION BATTERY
Why in news? • Recently, ISRO has approved commercial use of lithium-ion battery technology. Advantages of lithium-ion batteries over lead acid batteries • Weight: Lithium-ion batteries are one-third the weight of lead acid batteries. • Efficiency: Lithium-ion batteries are nearly 100% efficient in both charge and discharge while the lead batteries have the 70% efficiency. • Discharge: Lithium-ion batteries are discharged 100% versus less than 80% for lead acid. • Cycle Life: Rechargeable lithium-ion batteries cycle 5000 times or more compared to just 400-500 cycles in lead acid. • Voltage: Lithium-ion batteries maintain their voltage throughout the entire discharge cycle. Lead acid voltage drops consistently throughout the discharge cycle. • Cost: Despite the higher upfront cost of lithium-ion batteries, the true cost of ownership is far less than lead acid when considering life span and performance. • Environmental Impact: Lithium-ion batteries are a much cleaner technology and are safer for the environment. Common usage of Li-ion battery: Pacemakers, digital cameras, Smartphones, Solar Power Storage, battery backup systems, Rocket launcher etc.
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9.6. ARTIFICIAL LEAF
Why in news? Scientists at CSIR have developed an artificial leaf that absorbs sunlight to generate hydrogen fuel from water. Mechanism • Artificial leaf is an ultra-thin wireless device that consists of semi-conductors stacked in such a manner as to simulate the natural leaf system. • When visible light strikes the semiconductors electrons move in single direction thus producing electric current which almost instantaneously splits water into hydrogen. • A palm size artificial leaf can produce six litres of hydrogen fuel per hour thus making it extremely environment friendly. CSIR Council of Scientific and Industrial Research is India’s premier national R&D organisation established in 1942. • It operates as an autonomous body under Societies Registration Act 1860 and comes broadly under purview of Ministry of Science and Technology. • Prime Minister of India is the chairman of CSIR. Bionic Leaf uses solar energy to split water molecules into oxygen and hydrogen, and hydrogen-eating bacteria to produce liquid fuels from CO2.
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9.7. SUPERCRITICAL CO2- | BRAYTON CYCLE
Why in news? Indian scientists have developed a super critical carbon dioxide Brayton test loop facility that would help generate clean energy from future power plants Key facts • This is India’s first test-bed for next generation, efficient, compact, waterless super critical carbon dioxide Brayton cycle test loop for power generation. • The term “supercritical” describes the state of carbon dioxide above its critical temperature of 31°C and critical pressure of 73 atmospheres making it twice as dense as steam. • Today’s thermal power plants use steam to carry heat away from the source and turn a turbine to generate power. However, it could generate more power if, instead of steam, supercritical CO2 (SCO2) is used. Brayton cycle - A thermodynamic cycle using constant pressure, heat addition and rejection to spin the blades of a turbine, which can be used to generate electricity