118. STD's, vaginal discharge, urinary symptoms, vulvar lesions

Question 1

most common STD?

Answer 1

chlamydia- intracellular parasite- 70% asymptomatic

Question 2

what causes chlamydia? and what does it affect in both men and women?

Answer 2

bacteria- Chlamydia trachomatis. In women, chlamydial infection usually affects the neck of the womb (cervix) and the womb (uterus). In men, it usually affects the pipe through which urine is passed (the urethra) in the penis.

Question 3

tests for chlamydia?

Answer 3

urine sample, swab from the cervix

Question 4

meds for chlamydia?

Answer 4

azithromycin (favored because one-

time treatment, Azithromycin 1 g PO single dose) or doxycycline (100 mg PO bid x 7 d)

Question 5

if chlamydia has symptoms when do they appear?

Answer 5

2-6 weeks after infection

Question 6

MOA of azithromycin? what family of AB is it?

Answer 6

it is a macrolide

inhibit protein synthesis by blocking translocation

Question 7

DDx of vaginal discharge in?

Answer 7

gonorrhea, salpingitis, local (chemical irritants),

neoplasia (vulvar, vaginal, cervical, endometrial),

systemic (TSS, Crohns)

IUD, OCP (secondary to progesterone)

Question 8

symptoms of chlamydia?

Answer 8

dyspareunia, dysuria, frequency, no bacteria on culture, pelvic pain,

Question 9

Co-infection of chlamydia?

Answer 9

gonorrhea, therefore must treat this also

Question 10

Name 3 macrolide AB’s

Answer 10

azithromycin, clarithromycin, erythromycin

Question 11

another antibiotic used for chlamydia treatment?

Answer 11

Tetracyclines- doxycycline, minocycline

not to be used in pregnancy!!!