118 Microcirculation Flashcards

1
Q

Circulation methods for:

Gas Exchange

Water Soluble Solvents

Macromolecular Transport

A

Gas: through tissue, diffuses down gradient

Water solvents: tight junctions

Macro: through differeent capillaries (fenestrations, gaps, transcytosis)

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2
Q

van’t Hoff equation

A
  • Reflection Coefficient:
    • 0 : Perfectly permeable
    • 1 : Perfectly impermeable
  • Good approximation:
    • Only proteins have a reflection coefficient of 1
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3
Q

Starling equation: for capillary flow

A
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4
Q

How does net filtration pressure change along the capillary

A
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5
Q

Lymphatic circulation

A

parallel circulation

  • Microvalves
  • 2-4 L flow / day
  • Drains excess fluid from interstitium (net loss of fluid from capillary to interstitum)
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6
Q

Mechanisms for Control of Regional Blood Flow

A

Systemic:

  • oNeural Mechanisms
  • oHormonal Mechanisms

Local:

  • oMyogenic Mechanisms
  • oMetabolic Mechanisms
  • oEndothelial Mechanisms
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7
Q

Sympathetic Regulation of Blood Flow

A
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8
Q

Histimine Regulation of Blood Flow

A
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9
Q

Myogenic Regulation of Blood Flow

A
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10
Q

Metabolic Regulation of Blood Flow

A
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11
Q

Epithelial Regulation: Nitric Oxide

Blood Flow

A
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12
Q

Epithelial Regulation: Endothelin

Blood Flow

A
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13
Q

Active vs Reactive Hyperemia

A
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14
Q

Coronary Circulation

A
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15
Q

Cerebral Circulation

A
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16
Q

Pulmonary circulation

A
17
Q

Skeletal Muscle Circulation

A
18
Q

Skeletal Muscle: Muscle Pump

A