11.11.2019 - version 2 Flashcards

1
Q

The African swine fever virus can be inactivated by irradiation

A

F

inactivated by 2% NaOH, 0.3% formalin, hypochlorite for 30 min, or iodine

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2
Q

The ASF causes haemadsorption in cell cultures

A

T

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3
Q

The ASF infects the swine per os

A

T

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4
Q

The ASF virus replicates in lymphocytes

A

F

replicates in macrophages, monocytes, endothel, hepatocytes, tubular epithelium, and granulocytes, but NOT lymphocytes

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5
Q

In ASF cases abortion is never observed

A

F

all the 3 strains can cause abortion

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6
Q

In acute ASF cases the leading pathological finding are the haemorrhages

A

T

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7
Q

Vaccines are available to be used in the control of ASF

A
F
no vaccine (no antibody production)
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8
Q

ASF is shed in the saliva of the infected animals

A

T

saliva and nasal discharge. Can start to shed 48 hours prior to the appearance of CS

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9
Q

The FMD virus is very sensitive to the environmental conditions

A
F
non-enveloped and good resistance, esp in shadows, wet and cool sites of pastures. 
dirty stall = week 
Manure = 40 days 
frozen meat = months 
milk powder = years
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10
Q

The FMD virus can retain its infectivity in dried milk for months

A

T

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11
Q

All serotypes of FMD can be detected world-wide

A

F

7 serotypes: A and O found wordwide, C is rare

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12
Q

Swine shed FMD virus for a shorter time comparing to cattle

A

T
Swine: a few weeks, but amount is over 1000x more than cattle
Cattle: 0.5-3 years

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13
Q

Hedgehog is susceptible to FMD

A
T
ruminants (incl wild species), pig, guinea pig, hedgehog, dog and man
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14
Q

The primary replication site for FMD is the tongue mucosa

A

F

primary replication: pharyngeal and laryngeal mucosa

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15
Q

After immune response the FMD vesicles can recover fully

A

T

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16
Q

For laboratory tests FMD samples should be submitted in buffered transport
medium

A

T

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17
Q

Talfan disease is a disease of pigs

A

T

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18
Q

The clinical signs of Talfan disease are more sever than that of Teschen disease

A

F

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19
Q

Talfan disease can be seen in animals below 4 months of age

A

T

below 4 months of age (usually btw 3-8 weeks)

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20
Q

Flaccid paralysis is a typical clinical sign of Talfan disease

A

T

transient flaccid paralysis of hindlimbs

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21
Q

Pigs are infected with swine vesicular disease virus per os

A

T

per os or through skin abrasions

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22
Q

Swine vesicular disease virus can cause vesicles on the snout of pigs

A

T

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23
Q

Haemorrhages can be seen post mortem in the case of swine vesicular disease

A

F

no gross pathological changes as they don’t die from the disease

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24
Q

The mortality of swine vesicular disease is very high, it can be 50-60%

A

F

usually asymptomatic, and in case of any CS, the recovery is fast

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25
Q

Duck hepatitis A virus is shed in the faeces

A

T

shed in feces for several weeks

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26
Q

The resistance of duck hepatitis A is high

A

T

high resistance - can survive in bedding for 10 weeks

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27
Q

Germinative infection can happen in the case of duck hepatitis

A

F

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28
Q

Clinical signs of the duck hepatitis can be seen in all age groups

A

F

affects ducklings up to 6 weeks of age

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29
Q

The primary source of VES infection is sea-origin feed

A

T

primary source of infection: raw meat of sea animals, fish

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30
Q

Feline calicivirus infection can cause the limping of kittens

A

T
can cause “limping syndrome”, which may be immunocomplex mediated, and has been observed after immunization with live, attenuated vaccines

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31
Q

RHD virus can be propagated in cell culture

A

F

has to test vaccines in live animals

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32
Q

The orthohepevirus A causes clinical symptoms only in human

A

T

Is the causative agent of hepatitis E.
CS of animals: absent (maybe reproductive issues)
CS of humans: asymptomatic/moderate/fatal

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33
Q

The bursitis virus is very sensitive to the environmental conditions

A

F

high resistance - can survive in litter for 1-4 months (no envelope)

34
Q

The bursitis virus causes per os infection

A

T

35
Q

Clinical signs of Gumboro disease can be seen in chickens older than 8 weeks

A

F
chickens 0-8 (3-6) weeks
older than 8 weeks: carrier status, no CS

36
Q

Bursitis virus infection results In immunosuppression

A

T

37
Q

Togavirus are transmitted by mosquitoes

A

T

38
Q

Birds serve as reservoirs for Venezuelan horse encephalomyelitis virus

A

F
EEE: bird - mosquito cycle
WEE: bird - mosquito - rodent
VEE: horse - mosquito - horse

39
Q

Equine encephalomyelitis viruses can cause asymptomatic infections

A

T

it is age- and dose-dependent, and can cause inapparent infection

40
Q

Equine encephalomyelitis viruses are zoonotic

A

T
EEE: human among the dead-end hosts
WEE: human among the dead-end hosts
VEE: human can become clinically ill

41
Q

Reoviruses are sensitive to lipid solvents and detergents

A

F

42
Q

Orbiviruses are mainly arboviruses

A

T

43
Q

Bluetongue virus infects also horses and dogs

A

F

ruminants and sheep

44
Q

Bluetongue virus is also foetopathic

A

T

45
Q

Vaccination against bluetongue results serotype specific immunity

A

T

46
Q

Bluetongue outbreaks mainly occur is summer and autumn

A

T

seasonal, based on vector activity (midges)

47
Q

African horse sickness is zoonotic

A

F

48
Q

Zebras are not susceptible to African horse sickness

A

F
equids: horse, donkey, zebra (rarely other sp.)
elephant, camel, dog, ferret

49
Q

Horse encephalosis is endemic in Africa

A

T

50
Q

Rotavirus infects only mammals

A
F
6 (7) serotypes: 
A = majority of mammals and birds 
B = human, swine, cattle, sheep, rat (zoonotic) 
C = swine, rarely human (zoonotic) 
D = bird 
E = swine 
F + G = bird
51
Q

Rotaviruses are typically transmitted via the faecal-oral route

A

T

52
Q

Avian orthoreoviruses can cause inapparent infection in poultry

A

T

Can isolate several strains from clinically healthy birds -> many infections are subclinical

53
Q

The louping ill disease is seen in cattle in Great Britain and Scandinavia

A

F
species: sheep, rarely domesticated and wild mammals, humans
Place: UK, Scandinavia

54
Q

Serological cross reactions frequently occur between related flavivirus

A

T

serological cross reactions, sometimes cross protection too!

55
Q

The tick-borne encephalitis virus can be transmitted via consumption of raw milk

A

T

raw goat milk

56
Q

Pestivirus are zoonotic

A

F

57
Q

In utero infection with non-cytopathic BVDV can cause immunotolerance

A

T

58
Q

Mucosal disease can develop in cattle persistently infected with BVDV

A

T

59
Q

Bovine neonatal pancytopenia (BNP) is an immunopathy observed in immunotolerant, BVDV infected calves

A

F

Idiopathic disease. May have connection to BVDV vaccine as it is produced in bovine cells

60
Q

The border disease virus causes pneumonia in sheep

A

F

border disease is a pathogenic infection of pregnant ewes characterized by retarded development and CNS damage of lambs -> Hairy shaker syndrome

Ewes show no signs, and post-partum infections are subclinical

61
Q

Classical swine fever can retain its infectivity for 6 months in frozen meat

A

T

Survives in meat & blood for 1 month at 4°C or up to 1⁄2 year in frozen specimens

62
Q

CSF causes oronasal infection

A

T

63
Q

CSF infection results in immunosuppression

A

T

64
Q

In acute CSF skin haemorrhages and bloody nasal discharge can be observed

A

T

65
Q

CSF infection during the first half of pregnancy results in the birth of
immunotolerant piglets

A

T

66
Q

During necropsy enlarged bloody lymph nodes can be seen in CSF cases

A

T

67
Q

The boutons in the intestines are characteristic lesions in subacute CSF

A

T

68
Q

In vaccinated herds we mostly see the CSF clinical signs in 6-12 weeks old piglets

A

T
vaccination of pregnant sow with attenuated C-strain will provide maternal immunity for piglets until 6-12 weeks of age.
When the piglets have passed 3 months of age, they get their first vaccination.
remember! most countries don’t vaccinate, but eradicate.

69
Q

All bunyviruses are vectored by insects

A

F

all except Hantavirus are arboviruses

70
Q

Akabane virus causes foetal damages in dogs

A
F
affect ruminants (cattle, sheep, goat)
71
Q

Hantaviruses cause renal failure in human

A

T

72
Q

Nairobi sheep disease causes haemorrhagic enteritis in the infected animals

A

T

73
Q

Influenza viruses are classified into genera by their HA and NA proteins

A

F

NP and M1 proteins

74
Q

The M2 protein of influenza viruses serves as an ion channel important in the decapsidation

A

T

75
Q

The high virulence of some influenza A viruses is the result of mutations in the HA gene

A

T

76
Q

The NA protein has a role in the influenza virus release from the infected cells

A

T

77
Q

Antigenic drift means serials of point mutations in the HA and NA genes

A

T

78
Q

In birds all influenza variants can be detected

A

T

79
Q

The mortality of swine influenze is high

A

F

high morbidity, low mortality

80
Q

In poultry farms LPAI maybe be endemic without clinical signs

A

T