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Year 1 SBA revision > 111 - Obesity > Flashcards

111 - Obesity Flashcards

1
Q

What is obesity

A

BMI >30kg/m2

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2
Q

Complications of obesity

A

Increased risk of hypertension, myocardial infarction, Cerebrovascular accident (stroke), T2DM, Obstructive sleep apnoea, cancer, OA, GORD, gallstones,

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3
Q

Metabolic syndrome is:

A 
Central obesity plus 2 of:
High triglycerdides
High cholesterol
High BP
High glucose
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4
Q

Central obesity is

A

Determined by waist circumference, varies between ethnicities.

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5
Q

Lifestyle treatments for obesity

A

Diet and exercise

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6
Q

Pharmacological treatments fro obesity (classes not drugs)

A

Appetite suppressants
Lipase inhibitors
Anti-diabetic drugs

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7
Q

Surgical treatment for obesity indicated when

A

BMI >40/ >35+co-morbidity
18-55yrs
5yrs+obesity
No psych issues

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8
Q

Surgical options

A

Gastric banding
Sleeve gastrectomy
Gastric bypass
Bilo-pancreativ diversion +/- duodenal switch

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9
Q

How does Sibutramine work?

A

Appetite suppressant
Acts on Arcuate Nucleus
Inhibits serotonin reuptake - increase satiety
Inhibits noradrenaline reuptake - increases metabolism

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10
Q

How does Rimonabant work? Side effects?

A

Appetite suppressant

Blocks cannaboid receptors so decreases appetite. Withdrawn - side effects depression and suicide.

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11
Q

How does orlistat work? Side effects?

A

Pancreatic lipase inhibitor
Inhibits fat absorption
Side effects - steatorrhoea, faecal incontinence.

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12
Q

How does metformin work? Side effects?

A

Anti-diabetic - inhibits hepatic gluconeogenesis and increases insulin sensitivity.
Side effects - GI disturbance, lactic acidosis.

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13
Q

How does Rosiglitazone work?

A

Anti-diabetic drug, increases insulin sensitivity.

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14
Q

Why is gastric banding used?

A

Adjustable, reversible, less invasive, 50-60% of excess weight lost over 5yrs.

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15
Q

Downsides to gastric banding

A

Can slip
Pouch can enlarge
10% need revision

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16
Q

What is a sleeve gastrectomy?

A

Removal of greater curvature of stomach

17
Q

Benefits of gastric bypass

A

Laproscopic, decreases gastric capacity by 95% - good results.

18
Q

Role of leptin

A

Lowers appetite

19
Q

Role of Ghrelin

A

Gets you hungry

20
Q

What is dieting associated with?

A

Weight gain

21
Q

What protects against BMI increase?

A

Body satisfaction

22
Q

What can increase body dissatisfaction?

A

Thin ideal internalisation

23
Q

Gut embryology - What does the foregut form?

A

Mouth to duodenum (bile duct entrance)

24
Q

Gut embryology - What does the midgut form

A

Small intestine, caecum, appendix, ascending colon, 2/3 transverse colon.

25
Q

Gut embryology - What does the hindgut form?

A

1/3 transverse colon, descending colon, sigmoid colon, rectum.

26
Q

Describe the blood supply to gut

A

CSI
Coeliac trunk - foregut
Superior mesenteric - midgut
Inferior mesenteric - hindgut

Year 1 SBA revision (37 decks)

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