1.1.1 Meet the molecules Flashcards
1.1 The relationship between nucleic acids and proteins
What are nucleic acids?
They are nucleotide polymers ( meaning they are long molecules made up of connected bricks called nucleotides .
What is a nucleotide?
A relatively simple molecule made up of three components
- sugar
- a phosphate
- nitrogenous base
DNA stands for _________
deoxyribonucleic acid
RNA stands for _____________
Ribonucleic acid
What are the two major groups of nucleic acid?
- RNA
- DNA
What are the differences between RNA and DNA ?
- RNA contains a ribose sugar whilst DNA contains a deoxyribose sugar
- RNA contains adenine, guanine, cytosine and uracil , DNA replaces uracil with thymine
- RNA takes a single helix structure, DNA is a double helix
What is a protein?
Proteins are polymers like nucleic acids except their building block is an amino acid
How many amino acids are there?
There are 20
What are the four structural levels of proteins ?
- Primary
- Secondary
- Tertiary
- Quaternary
Describe primary structural level of proteins
Primary structure is the most basic level, describes the sequence of amino acids that make up a protein. There are peptide bonds between these amino acids
Describe the secondary structural level of proteins
Amino acids start to make some basic folds called alpha helixes and beta pleated sheets
Describe the tertiary structural level of proteins
When the protein begins to fold up further in strange ways. This is important in determining what a protein does
Describe the quaternary structural level of proteins
Some proteins take on quaternary structure ( not all ) This occurs when more than one protein get together and make a bigger protein
How are the structural levels of proteins related?
The order of amino acids ( primary ) determines where in the protein the a helices and b sheets occur ( secondary structure )
Together the primary and secondary determine the way that the protein ends up folding ( tertiary )
Only proteins that have complementary tertiary structures can make a quaternary protein