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KC Musculoskeletal Med #2 > #11: Pharm > Flashcards

#11: Pharm Flashcards

1
Q

Non-bx Drugs: (5)

A 
Methotrexate (Rheumatrex, Trexall)
Hydroxychloroquine (Plaquenil)
Sulfasalazine (Azulfidine)
Leflunomide (Arava)
Azathioprine (Imuran)
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2
Q

Non-bx drug onset and directions:

A
  • slow onset 1-6 months

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3
Q

For bio-similars to be effective they must demonstrate these 2 things:

A

1- high similarity to biologics

2- no clinical meaningful differences

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4
Q

What is the current take on bio-similars and biologics interchangeability?

A

They are NOT interchangeable and rq. contacting provider to make switch

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5
Q

What medications decrease uric acid filtration? (7)

A
  1. Diuretics (thiazide and loops)
    - Chlorthalidone
    - Hydrochlorothiazide
  2. Nicotinic acid (Niaspan)
  3. Salicylates (ASA >2g)
  4. Alcohol
  5. Levodopa/carbidopa
  6. Ethambutol/Pyrazinamide
  7. Ticagrelor (Brilinta)
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KC Musculoskeletal Med #2 (8 decks)

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