11 – Mitochondria I Flashcards
Mitochondria structure (7)
Intermembrane space
Outer membrane
Inner membrane
Matrix
Boundary membrane
Crista junction
Cristae
Mitochondria can form a complex of network of tubes
MOstly made of long filaments
Network is Dynamic, Can fragment & reform through processes: Fission & fusion
Mitochondria were…once
bacteria
Ancestral eukaryotic cells –> found prokaryote –> endosymbiosis (engulfed)
what drove the endosymbiosis?
Aerobic respiration
-use oxygen to slwo burn nutrients& produce max amount of energy (ATP) from this metabolic process
Mitochondria make their own…& segregate their own…
what is the questions arose from this?
ribosomes & segregate their own DNA
is this proof for endosymbiosis?
what proved endosymbiosis? and how does the experiment work
Sequence analysis – sanger
Sequences of superoxide dismutase
-E.coli with different superoxide dismutase = similar to mitochondrial superoxide dismutase
Mitochondria have their own
genetic code
-code has diverged
-want small genome
different mitochondria have different genome, different mitochondria for different groups of organisms have different changes
= due to ecolutionary pressure on having small circular DNA copy inside mitochondria
Mitochondrial complexes build with:
combination of nuclear & mtDNA genes
-protein encoded in nuclear
-protein encoded in mitochodnria on mitochondrial DNA