11 - HTN - Vasodilators - Nitroprusside, Diazoxide, and Fenoldopam Flashcards

1
Q

نحوه تجویز این داروها؟

A

parenteral

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2
Q

کاربردشون؟

100% امتحانی

A

فشارخون اورژانسی

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3
Q

Nitroprusside
ویژگی‌ها؟
3 مورد

A

1) light-sensitive
2) short-acting
3) must be infused continuously

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4
Q

Nitroprusside

مدت اثر؟

A

چند دقیقه

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5
Q

Nitroprusside

عملکرد؟

A

آزادشدن NO
از خود دارو
–>
افزایش cGMP

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6
Q

Diazoxide

از مشتقات چیه؟

A

تیازید

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7
Q

Diazoxide

آیا دیورتیک است؟

A

نه

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8
Q

Diazoxide
نحوه تجویز؟
2 مورد

A

1) intravenous boluses

2) infusion

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9
Q

Diazoxide

مدت اثر؟

A

چند ساعت

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10
Q

Diazoxide

عملکرد؟

A

بازکردن کانال‌های پتاسیمی
–>
هیپرپلاریزاسیون و ریلکس‌کردن ماهیچه

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11
Q

Diazoxide
عملکرد دیگه؟
(100% امتحانی)

A

کاهش آزادشدن انسولین
–>
درمان هیپوگلیسمی ناشی از تومورهای تولیدکننده انسولین

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12
Q

Fenoldopam

چیه؟

A

آگونیست گیرنده دوپامین

D1

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13
Q

Fenoldopam
با فعالسازی گیرنده دوپامین دی1
چ اتفاقی میفته؟

A

اتساع شدید عروقی

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14
Q

Fenoldopam

نحوه تجویز؟

A

IV infusion

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15
Q

Fenoldopam

مدت اثر؟

A

کوتاه

10 دقیقه

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16
Q

Nitroprusside

پاسخ جبرانی بدن؟

A

Salt and water retention

17
Q

Fenoldopam
پاسخ جبرانی بدن؟
2 مورد

A

1) Salt and water retention

2) tachycardia