11 DRUG DOSES (24)

Question 1

DDAVP* DOSE in Haemophillia/Von Willebrands

*aka??

Answer 1

• DDAVP is aka Desmopressin, its Vasopressin without the vasoconstriction.
• 6-12 mcg IV

Question 2

VITAMIN K DOSE for WARFARIN reversal

Answer 2

• VITAMIN K (KONAKION) 10mg IV or IM, works in 24h

Question 3

PROTAMINE DOSE FOR HEPARIN REVERSAL

Answer 3

• 1mg PROTAMINE reverses 100 u of Heparin,
• or 1x 50mg Amp per 5000u

Question 4

PROTHROMBINEX DOSE for WARFARIN reversal

Answer 4

• 50 u/kg IV (or 6 x 500u Amps): works immediately

Question 5

NOVO-7 DOSE

Answer 5

• 90 mcg/kg slow IV 2/24

Question 6

TRANEXAMIC DOSE (TXA) in Coagulopathy

Answer 6

• 1g IV over 10/60
• then again over 8h (in 50 mls NS at 6mls/h)
• not into a blood or 6% HES line

Question 7

MANNITOL DOSE for raised ICP

Answer 7

• 20% Mannitol, 2-5 ml/kg

Question 8

PHENYTOIN DOSE FOR HEAD INJURY

Answer 8

• LD 15mg/kg slow IV,
• then 300 mg daily

Question 9

KEPPRA DOSAGE

Answer 9

• LD = 20mg/kg slow IV

Question 10

NASAL FENTANYL DOSE

Answer 10

• 1.5mcg/kg via MAD
• prime first, use a screw lock syringe, give rapidly

Question 11

SINGLETON ISUPREL MIX

Answer 11

• 1mg in 250mls 5%D
• comm at 4mcg/min = 60 ml/h

Question 12

MEDSTAR ADRENALINE INFUSION

Answer 12

• 3mg in 50mls (60mcg/ml) 1-100ml/h (NORAD identical)

Question 13

MEDSTAR AMIODARONE INFUSION

Answer 13

• 300mg in 50mls over 1hr then 5ml/h

Question 14

MEDSTAR GTN INFUSION

Answer 14

• mix 25mg in 50mls (500mcg/ml)
• run at 1-50ml/h, commencing at 5

(1 Anginine = 600mcg, 1 GTN spray = 400mcg)

Question 15

MEDSTAR PROPOFOL INFUSION

Answer 15

• neat Propofol, run at 1-20 ml/h

Question 16

MEDSTAR SALBUTAMOL INFUSION

Answer 16

• 3mg in 50ml NS (60mcg/ml: same as Adren)
• LD = 4mls slow IV (240mcg) then 1-20ml/h

Question 17

HYPERTONIC SALINE DOSE FOR RAISED ICP

Answer 17

• 7.5% Saline, 4ml/kg

Question 18

MEDSTAR M&M mix

Answer 18

• Morphine 60 mg + Midaz 30 mg in 60 mls
• run at ~ 5mls/h

Question 19

VASOPRESSIN DOSE FOR SEPSIS or DI (FMC)

Answer 19

• mix 20u in 40mls
• give 1 ml stat, then 4-0 ml/h

Question 20

REMIFENTANYL DOSE FOR ANAESTHESIA

Answer 20

• 2mg in 50mls, (40mcg/ml)
• run at 5-100ml/h, comm at 25

Question 21

LIPID RESCUE DOSE

Answer 21

• 100 mls of 20% INTRALIPID IV stat
• rpt as needed

Question 22

DANTROLENE DOSE

Answer 22

• 2.5mg/kg IV
• rpt as needed

Question 23

AMINOPHYLLINE IN ASTHMA

Answer 23

• LD 6mg/kg slow IV then infusion

Question 24

MAGNESIUM DOSE IN ASTHMA

Answer 24

• 1 x 5ml amp x 49% = 2.5g = 10 mmol slow IV (kids 25mg/kg, = 1/100 amp per kg)