11 - Bacterial Infections Of Skin Flashcards
List of bacterial infections of skin
Impetigo Erysipelas Cellulitis Slistering distal dactylitis Folliculitis Sycosis barbae Furnicle Pseudomonas folliculitis and cellulitis Trichomycosiasis axilaris Erythasma Pitted keratolysis
What accounts for the maj of skin and soft tissue infections?
Staphylococcus aureus and group A beta-hemolytic streptococci
S. Aureus causes?
Invades the skin and causes
- impetigo
- folliculitis
- cellulitis
- furuncles
Elaborations of S. Aureus causes?
Leasions of bullous impetigo and SSSS
What does group A beta hemolytic strep cause?
Impetigo
Erysipelas
Cellulitis
Lymphangitis
Beta hemolytic strep causes?
Non bullous impetigo
Aka impetigo contagiosum
Progression of beta hemolytic strep - non bullous impetigo?
Starts as stratum corneum pustule or vesicle -> ruptures to expose a red moist base
Progresses to adherent “honey crusted” weeping lesions
Pt population for beta hemolytic strep - non bullous impetigo?
Kids 2-5
Warm moist climate
Poor hygeine
Beta hemolytic strep - non bullous impetigo often comes with?
Staph
Non derm symptom of beta hemolytic strep - non bullous impetigo?
regional LAD
Tx for beta hemolytic strep - non bullous impetigo?
Cool or warm soaks (remove crust)
Control infection (bactroban)
Systemic abx prn
- doxy
Dressing to prevent spread
Isolate pt
Beta hemolytic strep - eryspelas is aka?
St. Anthony’s fire
What is erysipelas?
Superficial cellulitis of lymphatics
- erythema
- edema
- pain
Seen on: (2/2 vascular insufficiency)
- face
- ears
- legs
Presentation of Erysipelas?
Lymphatic cellulitis
Prodrome
Slightly raised plaque w sharp demarcation
Red, warm, tender
ILL w malase, fever, nodes
WBC elevated
Tx for erysipelas?
Systemic abx
- oral
- IV
Cephelexin, diclox etc
cellulitis?
infection that extends into sub Q
Etiology of cellulitis?
GABHS (MC)
Staph
H. Flu (kids <2)
Pseudomonas (DM)
Where does cellulitis present?
Usually areas compromised by stasis/lymphedema
cellulitis presentation?
- erythema, edema, TTP (diffuse)
- no sharply defined border
- red streaks w swollen nodes
- vesicles or bullae
- dusky red skin
- constitutional ssx
- H WBC
cellulitis tx?
Cool compress
Elevation
Outpatient - dicloxacillin, cephalexin Inpatient - IV Nafcillin - IV vancomycin
Pesudomonas (DM)
- aminoglycosides
H. Flu
- cephalosporins
blistering distal dactylitis is?
Superficial infx of anterior fat pad of fingertips
blistering distal dactylitis is MC seen in?
Kids 2-16
Progression of blistering distal dactylitis ?
Faint erythema, Vesicles to oval 1-3cm bullae and exfoliation
Tx for blistering distal dactylitis?
I/D
Oral (anti-strep) abx x 10 days
Carriers of strep like to keep it?
Nasal
Axilla
Groin
Perianal area
MC secondary invader?
Staph aureus
Constitutional symptoms w Staph?
Nope
Staph toxin?
Epidermolytic toxin as in SSS or bullous impetigo
Staph aureus - bullous impetigo
Caused by toxin release in epidermis -> cleaving
- staph only (usually)
Bullous lesions are?
Less exudative crusting
- 1 or more vesicles enlarged rapidly to form bullae
- turn from clear to cloudy
Describe bullous impetigo?
Bullous lesion where the center collapses and leaves a TUBE-LIKE RIM
HONEY CRUST at center
- removal leaves bright red, moist base, that oozes
She said “youre taking the inter-tube down the staph river”
Tx for bullous impetigo?
Strict hand washing
Warm/coal soaks (remove crusts)
Muciprocin ointment
Systemic abx PRN
What is SSSS?
Staph scalded skin syndrome
- more diffuse form of bullous impetigo
What is folliculitis?
Inflammation of hair follicle
Typically caused by infection, chemical irritation, or physical injury
Think makeup, motor oil, steroid therapy
MC form of infectious folliculitis?
Staph folliculitis
- comes from the nose
Folliculitis workup?
Culture
- scrape and put on cotton swab
Tx for folliculitis?
Removal of occlusion/irritants etc
Good skin hygiene
Benzyol peroxide
Systemic abx
Long term scalp folliculitis?
Treat for folliculitis decalvans
What is sycosis barbae?
Inflammation of entire follicle
- staph impetigo of beard
- spread by razor
Tx for syscosis barbae?
Same as staph impetigo
- bactroban
- oral abx prn
Severe sycosis barbae?
Eval for dermatophyte infx
- remove hair for culture
Furncle vs carbuncle?
Furuncle - boil/abscess - walled off collection of pus
- painful
- firm
- fluctuant mass
Carbuncle - multi furncles
Furry uncles get together and get in a car…
Where do furuncles and carbuncles present?
Friction prone or traumatized areas
- thighs
- buttocks
- groin
- axillar
- waist
Tx for furuncle/carbuncle?
Primary: I/D
- moist heat to localize/spontaneously rupture (can also ease I/D)
Systemic abx prn
- not usually necessary
MRSA?
Consider w recurrent furnculosis
- mupirocin
- chlorhexidine/bleach baths
Abx for MRSA?
Septra
Clindamycin
Ecthyma?
Jungle sores
- like impetigo but worse
Ecthyma lesion?
Localized Thick Crusted Exudative Tumor-like lesion
Ulcers w crust
Heals w scar
Common on legs
Ecthyma tx?
Warm/coal soaks (remove crust) Good hygiene Dry dressing Mupirocin Dicloxacillin Cephalexin
This gram neg organism is not part of the normal flora?
Pseudomonas aeruginosa
Seen in sugar aids pts
Pseudomonas aeruginosa causes?
Green pigment
- pyoverdin - seen on wood light
- light green
Fruity, grape like odor
Pseudomonas folliculitis is aka?
Hot tub folliculitis
Presentation of pseudomonas folliculitis?
Hx of hot tub 8hrs-5 days ago
Often seen on bathing suit lines
Multiple pruritic, round, urticarial plaques w/ central papule or pustule
Malaise w low grade fever
So i got drunk and got in a hot tub, what now?
Showering will not help so, just pray i suppose
Fortunately its usually a self-limiting disease (7-10 days)
Tx for pseudomonas folliculitis?
Antihistamine - hydrozyzine (atarax) PRN Vinegar soaks (acetic acid) Domeboro’s Burrows
Ciprofloxacin if severe
Pt population for pseudomonas cellulitis?
Debilitated sugar aids pt
pseudomonas cellulitis is?
2/2 infasion of tinea of toe webs or groin Bed sores Stasis ulcers Burns Grafted areas Under foreskin Or following injury
pseudomonas cellulitis is encouraged by?
Occlusion and or suppression of normal flora w broad spectrum abx
Seen in swampy environment
pseudomonas cellulitis can also be found?
Around ear
- due to external otitis
pseudomonas cellulitis tx?
DM - blood sugar
- watch for sepsis
Acetic acid
Domeboro (aluminum acetate)
Systemic abx
- oral cipro
- IV aminoglycosides
Severe inf
- clindafloxacin IV
Pseudomonas toe web infection?
Between 4th and 5th toe
Caused by moisture
Thick white macerated skin
Green fluoresence (woods light)
Pseudomonas toe web infection commonly mixed w?
Candida
Or other bacteria
Pseudomonas toe web infection txt?
Keep clean and dry
- sandals
Acetic acid soaks
Drysol (aluminum chloride)
What is trichomycosis axillaris?
Corynebacterium infection of the hair of the axilla
Describe trichomycosis axillaris?
Whitish or colored hair
Associated w heavy sweating
Malodorous (very)
Tichomycosis axillaris txt?
Shave area Topical erythromycin Topical naftifine (naftin) Control hyperhidrosis - antiperspirants - drysol
What is naftifine (naftin) normally used for?
It is for superficial fungal (tinea)
Also has antibacterial properties
MC site for erythrasma - C. Minutissimum?
4th interdigital space
Other sites for erythrasma - C. Minutissimum?
Bilateral inguinal
Axillae
Inframammary fold
Describe erythrasma - C. Minutissimum?
Macular
Brown-red
Scaly
Noninflammatory
Itches
Burnes
Looks like T. cruris
Hwo to differentiate T. Cruris from C. Minutissimum?
KOH
Woods lamp
What does C. Minutissimum look like under a woods lamp?
Coral red fluorescence
- due to porphyrins produced by organism
Tx for erythrasma?
Keep clean and dry
Systemic (pick one)
- erythromycin
- clarithromycin
Topical (pick one)
- erythromycin
- clindamycin
- miconazole
- clotrimazole
Your pt presents with multiple 1-3mm pits to wt bearing areas of the feet
Pitted keratolysis
What causes pitted keratolysis
caused by micrococcus sedentarius which produces an enzyme that digests keratin
Symptoms of pitted keratolysis
1-3 mm pits to wt bearing areas
Hyper hydrosis
Malodor
Sliminess of skin
Pitted keratolysis is associated with?
The tropics
Occlusive footwear
Pitted keratolysis tx?
Clean daily
Promote dryness
Change socks
Rotate footwear
Drysol (20% aluminum chloride)
Topical ( pick one)
- erythromycin
- Clindamycin
- mupirocin
Oral (alternate treatment)
- erythromycin
What do you get from a pampered cow?
Spoiled milk