11 And 12 Allergic Dermatoses Flashcards
Type 1 is what mediated
I’ve
Type 2 is what mediated
IgG or IgM
Type 3 is what mediated
Immmune complex
Flea dermatitis is what type of hypersensitivity
I and IV
Cats clinical presentation of flea dermatitis
Tail, military dermatitis, indolent ulcer
With military dermatitis what do you find
Eosinpils
Flea can detect
Movement and CO2
Female flea lays eggs the eggs go
Into the environment
What treats flea in environment
Knockout spray
No insecticide can kill
Flea pupa
Canine Atopic Dermatitis
Hereditary, Pruitt I, T cell driven inflammatory skin disease involving interplay between skin barrier, allergen sensitization , and microbial dysbosis
Clinical presentation of AD
Chronic pruritus , skin inflammation ,
What is the typical distribution of skin lesions with AD
Face, ears, axil late, groins, fleural area, feet
AD is what type of diagnosis
Clinical diagnosis
Rule in AD with
Signalmen eat, history
Non AD dogs can stilll be positive for
Allergen specific IgE serological test
Favrots criteria
Less 3, indoor, corticosteroids resposonive pruritus, yeast infections, affected fron feet, afforestation ear pinnate, non affected ear margins, non affected dorsal lumbar
Less than 1 year what can u suspect
Ectoparasite and food allergies
Typical age for AD
1 - 3 years
Adult suspicions
Pruritus skin , environmental change, food allergy
Will patient with AD respond to corticosteroid
Yes
Canine scabies is more common where on dog
Outside
What reflex can you try with scabies
Pinna pedal
How do you DX scabies
Superficial skin scraping
Treatment trial for scabies
Isoxazolines
Unique clinical signs of scabies to rule out atopic dermatitis
Non affected ear margins
Key clinical sign of flea dermatitis that rules out
Non affected ear margins
Key clinical sign of flea dermatitis that rules out
Non affected dorsal lumbar area
How to DX demodicosis
Deep skin scraping
Itchy dog will not exclude
Demodicosis
What triggers AD
50% environment and 15% food
Treatment options for environmental AD
Allergen specific immunotherapy, glucocorticoids, cyclosporine,
ASIT mechanism
Desensitizes the immune system by exposing it to allergens
Glucocorticoids mediated
Arachidonic acid cascade and cytokine transcription
Cyclosporines inhibits
T cells
Oclacitinb and llunocitinib inhibit
JAKs
Lokivetmab specifically neutralizes
IL - 31
What is the specific cytokine playing roles in AD in dogs
IL - 31
Pathomechanism for feline atopic syndrome
Hypersensitive to food and environmental allergens
4 phenotypes of feline atopic skin syndrome
Military dermatitis, self induced alopecia, head and face pruritus, esoinphilic granuloma complex
Diagnosis of feline atopic skin syndrome
Clinical diagnosis
Cytologic for feline AD
Eosinophils
Pathomechanism of allergic contact dermatitis
Type IV
Pathomechanism of allergic contact dermatitis
Delayed reaction to Hapten
Hapten come from
Plants, topical, chlorine
Sensitiatzion stage of allergic dermatitis
The they elicit of dermatitis
Pathomechanism of irritant contact dermatitis
Non immune mediated reaction
Does contact dermatitis have senstitiacion stage
No
Clinical signs of allergic contact dermatitis
Pruritus and erythematous papular eruption
DX of allergic contact dermatitis
Clinical signs, history and patch test
Treatment of allergic contact dermatitis
Avoidance of allergens or symptomatic treatment
Pathomechanism of canine eosinophilia folliculitis
Eosinphilic allergic reaction triggered by arthropod or insect bites
Clinical presentation of Canine eosinphilic folliculitis
Sudden, nasal bridge papules, otherwise healthy, painful?
Treatment for eosinphilic folliculitis
Glucocorticoids
Pathomechanism for feline mosquito hypersensitivity
Type 1 hypersensitivity to mosquito saliva
Clinical presentation of feline mosquito hypersensitivity
Seasonal flares, pruritus, nasal bridge and pinnate
