11/2: Systemic Diseases II Flashcards
What are examples of autoimmune diseases?
Rheumatoid arthritis
Systemic Lupus erythematous (SLD)
Sjogren’s syndrome
Diabetes (type 1)
Grave’s disease (hyperthyroidism)
This is a group of diseases that affect bones, joints, and muscles
Rheumatic disease
What is an autoimmune and inflammatory disease that causes your immune system to attack itself?
Rheumatic disease
What are the 3 rheumatic diseases?
Osteoarthritis
Rheumatoid
Sjorgens syndrome
Almost everyone older than 60 develops what to some degree?
Osteoarthritis
Is osteoarthritis an autoimmune disease?
No
Can you affect TMJ with osteoarthritis?
Yes
Is rheumatoid arthritis autoimmune?
Yes
What is more severe, osteoarthritis or rheumatoid?
Rheumatoid
What is an autoimmune disease of unknown origin?
Rheumatoid arthritis
You get symmetric inflammation of joints, hand, feet and knees in what?
Rheumatoid arthritis
What is the onset age of rheumatoid arthritis?
35-50 years
Rheumatoid arthritis is more prevalent in male or female?
Female (3:1)
Do you get multiple symmetric joint involvement in RA or OA?
RA
Do you get 1-2 joints involved in RA or OA?
OA
Do you get significant joint inflammation in RA or OA?
RA
Do you get pain usually without inflammation in RA or OA?
OA
Do you get morning stiffness lasting longer than 1 hour in RA or OA?
RA
Do you get morning stiffness lasting less than 15 minutes in RA or OA?
OA
You get systemic manifestations such as fatigue, weakness, and malaise in RA or OA?
RA
You get heberden nodes of DIP joints in RA or OA?
OA
You get no systemic involvement in RA or OA?
OA
What is the most common and most serious type of lupus?
Systemic Lupus erythematous (SLE)
What is a chronic inflammatory disorder that affects both internal and
external systems of the body?
Systemic Lupus erythematous (SLE)
Who does Systemic Lupus erythematous (SLE) effect?
Women at a rate of 6:1 and often occurs between 14-44 years of age when estrogen levels are at their highest
What is the typical presentation of SLE?
A women with polyarthritis and a butterfly-shaped erythematous rash across the nose and cheeks
What kind of rash do you get from SLE?
Mild to severe and include itching and feeling of warmth
In what % of patients with SLE is skin involved?
85%