10/26: Systemic Diseases Flashcards
What is a general term for pulmonary disorders charactrized by chronic airflow limitation from the lungs?
Chronic obstructive pulmonary disease (COPD)
What is the 3rd leading cause of death in 2020?
COPD
Is COPD fully reversible?
No
COPD encompasses what 2 main diseases?
- Chronic bronchitis
- Emphysema
What is the recommended diagnosis of COPD?
Presence of septum production and dyspnea together with an abnormal measurement of lung function
This is chronic inflammation of the bronchi that produces excessive tracheobronchial mucus production and a persistent caught with sputum for at least 3 months in at least 2 consecutive years
Chronic bronchitis
This is permanent enlargement of the air spaces in the lungs that is accompanied by destruction of the air space walls without obvious fibrosis
Emphysema
The onset of COPD after what age?
40 years
What are patients with chronic bronchitis described as?
Sedentary, overweight, cyanotic, edematous and breathless
What are patients with COPD known as?
Blue bloaters
This is permanent enlargement of the air spaces in the lungs tha is accompanied by destruction of the air space walls without obvious fibrosis
Emphysema
What are patients diagnosed with emphysema known as?
Pink puffers because they demonstrated enlarged chest walls (barrel-chested appearance)
What does emphysema show as?
Weight loss with disease progression
Severe exertional dyspnea
Seldom coughing
lack of cyanosis
Pursing of lips with efforts to forcibly exhale air from the lungs
What are questions you should ask someone with emphysema or bronchitis?
How severe?
How long have you had it?
What medications are you
on?
Does it bother you to recline
completely?
Will the rubber dam be a problem?
What questions should you ask someone with shortness of breath?
how many blocks can you walk
before tiring?
can you walk two flights of stairs
without having to stop?
What is a condition in which the heart valves have been
permanently damaged by rheumatic fever
Rheumatic heart disease
When does heart valve damage start?
Shortly after untreated or under-treated streptococcal infection such as strep throat or scarlet fever
What can result in on-going valve damage?
An immune response causes an inflammatory condition in
the body
What can happen to heart valves over time?
Become inflamed and scarred over
What is a disorder of cognition that
consequently interferes with the daily
functions and results in a loss of
independence?
Dementia
What are the most common causes of dementia?
Alzheimer’s disease, vascular dementia,
& dementia caused by Parkinson’s
disease
When does prevalenze of dementia and alzheimer’s increase?
With age: 65y/o-
7% by age 85, more than 40%
What gender is more at risk?
Women because they live longer
What are symptoms of alzheimer’s disease?
Memory loss
Cognitive decline
Behavioral and
personality changes
What is the cause of alzheimers?
Unknown but appears to involve loss of cholinergic neurons
How often does genetic predisposition contribute to?
Less than 20% of all cases
What is the average lifespan after dx?
8 years
What is dental management of alzheimer’s disease?
Knowledge of the
stage of the disease, medications taken,
and the cognitive abilities of the patient
What do medications such as antipsychotics, antidepressants,
and anxiolytics contribute to?
xerostomia with increased risk for dental caries
Where are small endocrine glands located?
Bilaterally at the superior pole of each kidney
What is progressive destruction of the Adrenal Cortex, Usually due to autoimmune disease?
Primary adrenal insufficiency (addison’s disease)
What are chronic infectious diseases?
TB, HIV, Cytomegalovirus and
some fungal infections
What does primary adrenal insufficiency decrease?
Cortisol (stress hormones) and aldosterone
What does cortisol do?
Decreases inflammation, regulates blood pressure, increases glucose
What does aldosterone do?
Stimulates Na+ absorption by the kidneys
This is caused by pituitary disease or critical illness
2nd adrenal insufficiency
This is caused by process that impair function of the hypothalamus
3rd adrenal insufficiency
What is the most common cause of tertiary adrenal insufficiency?
Chronic use of corticosteroids