10.18 local delivery Flashcards
who started “local delivery?”
max (or matt?) goodson
why is there no alternative to SRP?
- mechanical removal of calculus
- removal of endotoxin
advantages of local delivery
- very high concentration at site of interest
- less chance of resistant organisms?
- more conservative therapy
disadvantages of local delivery
- only local action
- resistant organisms? (not really, maybe further away from the site of injection)
what are the three types of local delivery (products)?
- PerioChip
- Atridox
- Arestin
what abx is in each type of local delivery?
- PerioChip-chlorhexidine 2.5 mg
- Atridox-Doxycycline
- Arestin-minocyclin
gelatin matrix; 4 mm x 5 mm
PerioChip
Two part Carrier with a syring injection-multiple sites/teeth
atridox
one part syring, one tip per site
arestin
what are the side effects of chlorihexidine (mouthrinse)?
- non permanent stain
- tin type taste
benefits of chlohexidine
- broad spectrum antimicrobial
- minimal bacterial resistance
- minimal side effects
how long do the local delivery agents last?
PerioChip-days
Arestin and Atridox-weeks
-but their effects last weeks and months
what are the more specific components of Atridox?
- poly (DL-lactide) (PLA) 33%
- N-methyl-2-pyrrolidone (NMP) 57%
- doxycycline Hyclate 10%
local delivery vs systemic abx
Systemic antibiotics very effective in Aggressive Periodontitis
- Systemic antibiotics similar in effect to local delivery in chronic adult periodontitis
- Local delivery devices have similar efficacy
