1010 Final Review Flashcards
Symptoms of how you know Levodopa is wearing off?
Shuffling gait, tremor, poor coordination
Osteoblasts
Build bone cells.
Osteoclasts
Absorb bone cells.
How do you give dilated/phenytoins? What’s important to remember when administering?
IM is very irritating to the tissue and has erratic absorption so it must be IV or oral.
What is the mechanism of action for phenytoins?
Binds to sodium channel on nerve membranes and makes them less active.
Adverse effects of phenytoins?
Gum hyperplasia and abdominal discomfort.
Mechanism of action of carbamazepine?
Limits the spread of neuron excitation by altering the sodium channel of nerve membranes and slows/prevents re-firing of neurons.
Adverse reactions of carbamazepine?
GI distress
Ataxia
Pruritis
Rash
Weakness
Photo-sensitivity
Mechanism of action for ethosuximide?
Alters calcium channels on neuron membranes and reduces excitability.
Adverse reactions of ethosuximide?
Heartburn
Nausea/Vomiting
Dizziness
Drowsiness
Fatigue
Mechanism of action of phenobarbital?
Raises seizure threshold by enhances inhibition of neurotransmitter GABA causing CNS depression.
Adverse reactions of phenobarbital?
Drowsiness
Ataxia
Blurred vision
Mental status changes
Mechanism of action of valproic acid?
Raises seizure threshold by increasing activity of neurotransmitter GABA.
Adverse reactions of valproic acid?
Birth defects
Anemia
Luekopenia
Thrombocytopenia
Arrhythmia
Liver toxicity
Drugs that interact with anti-epileptics?
Antipsychotics
Antidepressants
Antimicrobial
Contraceptives
Cold medications
Aspirin
Diabetic drugs
Addison’s disease?
Low cortisol
Crushing’s disease
Excess cortisol
Medication given for hypothyroidism?
Levothyroxine.
Passive vs. Active immunity?
Active immunity occurs when your body’s immune system protects you from a pathogen, while passive immunity occurs when you receive immunity from another source.
Preload? What increases preload?
Volume of blood in the ventricles at the end of diastole.
Increased by hypervolemia, HF, and regurgitation of cardiac valves.
Afterload? What increase afterload?
Resistance the left ventricles must overcome to circulate blood.
Increased by HTN and vasoconstriction.
How to diuretics affect preload and afterload?
They decrease preload by reducing the volume of blood returning to the heart.
Adverse effects of decongestants?
HTN
Palpations
Blurred vision
Tachycardia
Anxiety
Tremors
What typically happens to vital signs when afterload is decreased?
Decrease in BP.
What electrolytes are wasted when using diuretics?
K+
Na+
Ca+
What is SABA?
Short-acting β2-adrenergic agonists, a bronchodilator.
Albuterol, always keep SABA with you at all times!
What do mucolytics do in someone who is diagnosed with COPD?
Thinning and loosening thick mucus in the airways, making it easier to cough up and clear the airways, potentially reducing the frequency and severity of COPD exacerbation.
How do you store nitrates?
Room temperature in a dark container.