10.1 Disorders of Autonomic Nervous System Flashcards

1
Q

Divisions of autonomic nervous system

A
  • sympathetic
  • parasympathetic
  • enteric
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2
Q

fxn of nerve fiber type Aalpha

A

proprioception, somatomotor

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3
Q

fxn of nerve fiber type Abeta

A

touch, pressure

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4
Q

fxn of nerve fiber type Agamma

A

motor of muscle spindle

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5
Q

fxn of nerve fiber type Adelta

A

pain esp cold, touch

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6
Q

fxn of nerve fiber type B

A

preganglionic autonomic

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7
Q

fxn of nerve fiber type C

A

thermal, heat pain, mechanoreceptor; postganglionic autonomic

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8
Q

order nerve fiber types from largest to smallest diameter

A

Aalpha, Abeta, Agamma, Adelta, B, C

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9
Q

order nerve fiber types from highest to lowest conduction velocity

A

Aalpha, Abeta, Agamma, Adelta, B, C

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10
Q

heat defense response

A
  • w/ incr core temp –>warm sensory neurons in medial preoptic hypothalamus activated –> incr skin vasodilation and sweating
  • inhibited by cutaneous cold receptors
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11
Q

cold defense response

A
  • tonically have warm sensitive neurons inhibiting cold responsive neurons of dorsal medial hypothalamus (DMH)
  • cold exposure –> decr warm sensitive neuron activity –> activate BOTH heat conserve (skin vasoconstriction) and heat gen (via shivering and nonshivering mech)
  • via PAG and nucleus raphe pallidus
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12
Q

Adie’s pupil

A
  • tonic dilated pupil (but does react to prolonged light?)
  • near response&raquo_space; light response
  • post-ganglionic short ciliary nerve lesion
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13
Q

Adie’s pupil with areflexia

A

Adie’s syndrome

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14
Q

Adie’s syndrome

A

Adie’s pupil with areflexia

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15
Q

Adie’s pupil with anhidrosis

A

Ross’ syndrome

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16
Q

Ross’ syndrome

A

Adie’s pupil w/ anhidrosis

17
Q

Horner’s syndrome

A
  • miosis (constricted pupil)
  • anhydrosis
  • ptosis (eyelid droop)
18
Q

Horner’s syndrome - full

A
  • ptosis
  • meiosis
  • anhidrosis
  • impaired flushing (Harlequin syndrome)
  • lower lid elevation (reverse ptosis)
  • enopthalmos
19
Q

Approach to pt w/ autonomic dysfxn

A
  • focal
  • regional
  • generalized
  • PNS features v. CNS features v. autonomic features only
20
Q

autonomic periph neuropathies

A
  • diabetes
  • amyloidosis
  • hereditary autonomic neuropathy
  • immune mediated autonomic neuropathy
  • infection assoc neuropathy
  • toxic autonomic neuropathy
  • idiopathic autonomic neuropathy
21
Q

autonomic control of GI tract

A
  • extrinsic - SNS and PNS

- intrinsic - enteric nervous system

22
Q

What modulates the enteric nervous system?

A

extrinsic nervous system

23
Q

What are the intrinsic plexuses of enteric nervous system?

A

Auerbach’s and Meissner’s plexus

24
Q

autonomic response to orthostatic change?

A
  • blood pooling in dependent areas
  • baroreceptor mediated reflex response
    (vasomotor, cardiac, endocrine)
  • SBP decr 5-10mmHg and DBP incr 5-10 mmHg
  • HR incr 10-20 bpm
25
Q

orthostatic hypotension

A
  • decr in SBP by 20mmHg OR DBP by 10mmHg or more

- accompanied by sx of orthostatic intolerance

26
Q

sx of orthostatic hypotension

A
  • lightheadness and dizziness
  • weakness and fatigue
  • headache and neck pain
  • leg buckling and limb jerking
  • visual blurring
  • cognitive slowing
27
Q

central autonomic disorders

A
  • alpha synucleinopathies
  • MS
  • brain tumors
  • CVD
  • syringobulbia
  • Wernicke’s disease
  • myelopathy