10: Clinical overview of Hypothalamus and Pituitary Disorders- Beverly Flashcards
increased midnight cortisol compared to normal people but apparently normal in the mornings
cushing’s syndrome
_% of healthy adults on MRI or post mortem exam will have a pituitary adenoma
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most incidentalomas are of no clinical importance but all pts with a lesion should be referred to an endocrinologist
most abundant ant. pit. hormone
growth hormone
treatment for GH hypersecretion
- surgery
- somatostatin analogues
- dopamine agonist
- GH antagonist
- radiation
what inhibits PRL?
dopamine
most common benign neoplasm
hyperporlactinemia - prolactoma
treat with dopamine agonist, surgery, or radiotherapy
ACTH deficiency
Addison’s disease
treat with a glucocoticoid like hydrocortisone or prednisone
ACTH hypersecretion
cushing’s syndrome
moon face buffalo hump purple striae diabetes acne
when are FSH and LH secreted?
every 60-120 min
what would need to be taken to induce ovulation in a woman with FSH and LH deficiency?
hCG
hCG to restore fertility
attenuated LH and hypogonadism due to compression of pituitary stalk with optic chiasm causing visual problems
FSH and LH hypersecretion
TSH hyper v. hyposecretion
heat intolerance, palpitations, weight loss (could be Graves)
weight gain, puffy face, fatigue, dry skin
ADH deficiency
diabetes insipidus
large volumes of dilute urine
ADH hypersecretion
syndrome of inappropriate ADH
decreased volumes of highly concentrated urine
pituitary apoplexy?
endocrine emergency with severe headache, visual changes..
due to intrapituitary hemorrhagic vascular events
if postpartum = sheehan’s syndrome
