10

Question 1

What does Platelet Derived Growth Factors do?

Answer 1

Produced by Platelet blood cells

Binds to Tyrosine Kinase receptors of fibroblasts

Question 2

Tyrosine Kinase binding to fibroblasts triggers?

Answer 2

Transduction pathway to allow cells to pass the G1 checkpoint and divide

Question 3

Fibroblasts will only divide when?

Answer 3

With a medium that contains PDGF

Question 4

When is PDGF released?

Answer 4

Due to an injury

Question 5

What is density dependent inhabiting

Answer 5

When a gap forms and cells grow to fill the gap

At high density the amount of growth is insufficient

Question 6

What is Anchorage Dependence?

Answer 6

To divide they must be anchor ed to a substratum

Question 7

The controls of Anchorage Dependence appear to be?

Answer 7

Pathways involving the plasma membrane proteins and elements of the cytoskeleton

Question 8

Cancer cells don’t have?

Answer 8

Anchorage dependence or density dependence

Question 9

Cancer cells do not stop dividing?

Answer 9

When growth Factos are deleted

Question 10

Cancer cells may have?

Answer 10

Make their own growth Factors

Or an abnormal cell cycle