10

Question 1

Decreases abs of levothyroxine?

Answer 1

bile acid binding agents, Fe, Ca, Aluminum hydroxide, PPIs, sucralfate

Question 2

Decreases levothyroxine by incr TBG?

Answer 2

E, tamoxifen, raloxifene, heroin, methadone

**incr dose

Question 3

Affects levothyroxine by decr TBG?

Answer 3

androgens, GC, anabolic steroids, nicotinic acid

*decr dose

Question 4

Incr metabolism of levothyroxine?

Answer 4

rifampin, phenytoin, carbamazepine

Question 5

PID tx?

Answer 5

cef/doxy + clinda/gent

Question 6

Alz tx?

Answer 6

donepezil, rivastigmine, galantamine (rev ACHase inh)

memantidine if mod-severe

Question 7

drugs a.w incr K?

Answer 7

nonsel BB
ACEI
ARBs
digoxin
NSAIDs (decr P = decr renin/ald)
K sparing diuretics (amiloride, triamterene, spironolactone)

Question 8

drug a/w decr K?

Answer 8

hctz

Question 9

thyr CA a/w incr calcitonin?

Answer 9

medullary

Question 10

thry CA a/w Hurthle cells?

Answer 10

follicular and papillary

Question 11

S3 is due to…

Answer 11

incr cardiac filling pressure + turbulent blood flow

nml in kids, young adults, preg

abn if >40, CHF, rest CM, high output states

Question 12

Orbital cellulitis versus preseptal ?

Answer 12

orbital = ophthalmoplegia, pain with EOM, proptosis, vision changes

Question 13

Polymyalgia rheumatica:
lab abn?
tx?

Answer 13

incr ESR

CS

Question 14

Tx CML (bcr-abl)?

Answer 14

TK inh

Question 15

Electrolyte abn a/w vit D deficiency?

Answer 15

decr phos
decr Ca
incr alk phos

Question 16

Renal v thrombosis:
cause?
MC a/w…

Answer 16

decr AT III (pres: abdp, F, hematuria)

membranous glomerulopathy

Question 17

decr K on EKG:

Answer 17

U waves, flattened T waves, PVCs

Question 18

next step? unstable pt w inconclusive FAST…

Answer 18

peritoneal lavage

Question 19

1st line for stable chr angina?

Answer 19

BB (improves survival)

Question 20

tx actinomycosis?

Answer 20

amox

Question 21

amebiasis tx?

Answer 21

metronidazole

Question 22

Fanconi syndr pres:

Answer 22

glucosuria, aminoaciduria, phosphoturia, RTA type 2 (incr urine bicarb)

Question 23

RTA type 4 =

Answer 23

aldosterone resistance (2/2 obst uropathy and CAH)

Question 24

ITP is a/w…

Answer 24

HIV (may be 1’ pres)

Question 25

Paget’s of breast is a/w..

Answer 25

underlying adenocarcinoma

Question 26

sudden loss of vision + floaters =

Answer 26

vitreous hemorrhage (a/w DM retinopathy)

Question 27

S4 is due to…
nml in:
abn in:

Answer 27

stiff ventr

nml: older adults
abn: kids, ventr hypertrophy, acute MI

Question 28

1’ hyperald/Conns syndr:
hormone abn…
electrolytes?

Answer 28

decr renin, incr aldosterone

htn w/ incr Na, decr K, met alk

Question 29

ANA + anti-topo 1 =

Answer 29

systemic sclerosis

Question 30

chol screening guidelines:

Answer 30

men 35 yo, women 45 yo; q5y

Question 31

halos, redness, nonreactive/mid-dilated pupils

dx?

Answer 31

acute angle glaucoma

gonioscopy* or tonometry

Question 32

Blasto
pres?
tx?

Answer 32

lytic bone lesions, pulm s/s, skin ulceration

itra or ampho B

Question 33

Tx SIADH (by severity):

Answer 33

1. fluid rest, salt tablets, loop (if Uosm >2x serum osm)
2. hypertonic saline to incr Na to 120, then (1)
3. hypertonic saline bolus until s/s resolve +/- vasopressin R antagonist (-vaptin)