1

Question 1

Tx Xlinked agammaglobulunemia?

pres?

Answer 1

IVIg

absent/decr lymphoid tissue, nml Tcells, very low B cells

Question 2

Type 4 RTA labs?

Answer 2

nonAGAP met acidosis, chr hyperK, incr Cr, hypoNa

*a/w DM

Question 3

Cause of mixed resp alk and met acidosis in ASA toxicity?

Answer 3

tachypnea (acts @ medulla) + incr prod with decr elim of organic acids

Question 4

Path of Reye’s?

Answer 4

microvesicular fatty infiltration + hepatic mitochondria dysf

Question 5

Pres of HIV-asst’d CMV esophagitis?

Answer 5

deep, linear ulcers and distal esophagitis

Question 6

Pres of HIV-asst’d HSV esophagitis?

Answer 6

vesicles + round/ovoid ulcers

Question 7

Pres of HIV-asst’d candida esophagitis?

Answer 7

white plaques + oral thrash (*MCC)

Question 8

Dx type 2 HIT? Tx?

Answer 8

serotonin release assay

d/c heparin, start argatroban or fondaparinux

Question 9

A/w dermatomyositis?

Answer 9

interstitial lung disease, esoph dysmotility, Raynaud’s

Question 10

Test to determine if Rhogam dose was sufficient?

Answer 10

Kleihaur-Betke

Question 11

PE in cor pulmonale?

Answer 11

periph edema, incr JV pressure, loud S2, pulsitile liver, tricuspid regurg

Question 12

Inf a/w hemochromatosis?

Answer 12

Listeria, Vibrio vulnificus, Yersinia enterocolitica

*also a/w hepatocellular carc

Question 13

Screen ALL preg women for:

Answer 13

syphilis, HIV, hep B

Question 14

Kallman syndrome hormone abn?

Answer 14

no GnRH, decr LH/FSH

Question 15

Tx KS?

Answer 15

thiazide, urine alkinization, allopurinol (if uric acid stones)

Question 16

Bone abn a/w decr vit D?

Answer 16

incr deposition of poorly mineralized osteoid

Question 17

Bone abn a/w primary hyperparathyroidism?

Answer 17

loss of cortical bone mass

Question 18

Bone abn a/w incr vit A?

Answer 18

abundant mineralization of periosteum

Question 19

Bone abn a/w Paget’s?

Answer 19

increased osteoclastic reabsorption –> resorption and disorganized formation (causing a chaotic mosaic of lamellar and woven bone)

Question 20

How does synthroid dose change in preg/hypothyroidism?

T3/T4 levels in preg?

Answer 20

increase

increased T3/T4 due to decreased thyroid binding globulin

Question 21

Parvo B19 dx in immunocompetent vs immunocompromised host?

Answer 21

immunocompetent: B19 IgM
immunocompromised: NAAT

Question 22

Tx benign essential tremor? S/e?

Answer 22

primidone

can ppt acute int porphyria

Question 23

Dx vertebral osteomyelitis?

Answer 23

1) MRI, 2) CT-guided biopsy

Question 24

Warm autoimmune hemolytic anemia:
etiology?
dx?

Answer 24

drugs (PCN), viral inf, A/I (SLE), immunocompr, lymphoprolif d/o

direct Coombs +, anti-IgG, anti-C3

Question 25

Warm autoimmune hemolytic anemia:
pres/labs?
tx?

Answer 25

symptomatic anemia with incr retic, splenomeg
decr haptoglobin, incr LDH, spherocytosis

CS, splenectomy

Question 26

Cold autoimmune hemolytic anemia:
etiology?
dx?

Answer 26

Mono, mycoplasma pneumonia, lymphoprolif d/o

direct Coombs +, anti-IgM, anti-C3

Question 27

Cold autoimmune hemolytic anemia:
pres?
tx?

Answer 27

anemia, livedo reticuaris, acral cyanosis in cold

avoid cold, rituximab +/- fludaribine

Question 28

Screening test for HIV?

Answer 28

p24ag/ab

Question 29

Tx cong prolonged QT?

Answer 29

beta blocker and PM