10-20 mod 2 quiz Flashcards

1
Q

What is important about the sentinel node?

A

The sentinel note note is the first lymph node to which the primary tumor drains

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2
Q

What is angiogenesis

A

The development of new blood vessels within a tumor

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3
Q

What are the two broad ETIOLOGIC causes of cancer

A

The genetic and molecular mechanisms that transform normal self to cancer cells

External factors such as age hereditary and environmental agents

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4
Q

What are the two cancer associated genes

A

Protooncogenes and tumor suppressor genes

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5
Q

What are the three genetic events that lead to oncogene formation and activation

A

Point mutation chromosome no translocation and gene Amplification

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6
Q

What are the six molecular and cellular mechanisms that are known to facilitate the development of cancer

A
Defects in DNA repair mechanism
Defects in growth factor signaling pathways
Evasion of apoptosis
Avoidance of cellular senescence 
Development of sustained angiogenesis
Meta-stasis and invasion
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7
Q

What are the seven wrist factors that can lead to the development of cancer

A
Hereditary 
hormonal factors 
obesity 
immuno logic 
chemicals radiation 
and cancer-causing viruses
Environmental
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8
Q

Example of hereditary cancer

A

Breast cancer and ovarian cancer

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9
Q

What organs do hormones in the development of cancer target

A

Breast ovary prostate endometrium

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10
Q

Lifestyle factors that contribute to the development of cancer

A

Smoking alcohol chewing tobacco high fat low fiber diet high intake of smoked meats sun exposure obesity

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