10-20 mod 2 quiz Flashcards
What is important about the sentinel node?
The sentinel note note is the first lymph node to which the primary tumor drains
What is angiogenesis
The development of new blood vessels within a tumor
What are the two broad ETIOLOGIC causes of cancer
The genetic and molecular mechanisms that transform normal self to cancer cells
External factors such as age hereditary and environmental agents
What are the two cancer associated genes
Protooncogenes and tumor suppressor genes
What are the three genetic events that lead to oncogene formation and activation
Point mutation chromosome no translocation and gene Amplification
What are the six molecular and cellular mechanisms that are known to facilitate the development of cancer
Defects in DNA repair mechanism Defects in growth factor signaling pathways Evasion of apoptosis Avoidance of cellular senescence Development of sustained angiogenesis Meta-stasis and invasion
What are the seven wrist factors that can lead to the development of cancer
Hereditary hormonal factors obesity immuno logic chemicals radiation and cancer-causing viruses Environmental
Example of hereditary cancer
Breast cancer and ovarian cancer
What organs do hormones in the development of cancer target
Breast ovary prostate endometrium
Lifestyle factors that contribute to the development of cancer
Smoking alcohol chewing tobacco high fat low fiber diet high intake of smoked meats sun exposure obesity