10/20/2015 - Application of the Nursing Process in the MGMT of Pharmacology Flashcards
The process by which a drug passes into the bloodstream
Absorption
Exists in a person who exhibits an unusually low physiological response to a drug and who requires increases in the dosage to maintain a given therapeutic effect.
Drugs that commonly produce this effect are opiates, barbiturates, and ethyl alcohol
Drug Tolerance
A filtering mechanism of the capillaries that carry blood to the brain and spinal cord tissue, blocking the passage of certain substances.
A highly selective permeability barrier that separates the circulating blood from the brain extracellular fluid (BECF) in the central nervous system (CNS).
Blood-Brain Barrier
A severe allergic reaction that usually occurs immediately after the administration of a drug
Anaphylactic Reaction
The study of the effect of racial and ethnic differences/responses to prescribed medication.
For example, certain medications may work well at usual therapeutic dosages for certain ethnic groups but be toxic for others.
Incorporates pharmacogenetics, which can also vary by race or ethnic group
Ethnopharmacology
Clearance
Process by which a drug is converted to a less active form;
also called detoxification or metabolism
Biotransformation
The transportation of a drug from its site of absorption to its site of action.
Distribution
Severe side effects that may justify the discontinuation of a drug
Adverse Reaction
The process by which metabolites and drugs are eliminated from the body.
Excretion
Drug that inhibits cell function by occupying the drug’s receptor sites
Antagonistic Effect
The _______ is assigned by the United States Adopted Names (USAN) Council and is used throughout the drug’s lifetime
generic name