1-sedatives Flashcards
Doc for GAD
Buspirone
Drug used for chronic alcohol withdrawal
Diazepam
Drug used for insomnia with no rebound REM sleep
Ramelteaon
Drug safest that’s is used for pregnant epileptics
Phenobarbital
Barbiturates are inducers of what
Cyp450
Barb used to induce general anesthesia -fast acting
Thiopentone
How is thiopentone eliminated
Redistribution in peripheral tissues
Triazolam is a what? MOA ?
BenZo with a short half life of 2-3 hours used for insomnia
Increase stage 2nrem sleep and decrease rem sleep
What is the drug of choice for panic disorder and phobias
Alprazolam
Doc for severe seizures
Diazepam
Only benZo that is also a skeletal muscle relaxant by inhibiting spinal reflexes
Diazepam
Benzo that is to calm patient before surgery and causes anterograde amnesia
Midazolam
Date rape usage
BenZo- flunitrazepam
Barbs are contradicted in what patients
Acute intermittent porphyria pts
Drugs safer for pregnant
Z drugs
Buspirone
Partial agonist on 5-ht1A auto receptors
Antagonist for z drugs
Flumanezile
Barbs induce metabolism of what drugs
Phenytoin
Warfarin.
Reduce their therapeutic effects
Benzos with no active metabolite
Safe for elderly and compromised liver function
Oxazepam
Lorazepam
Three benzodiazepines available IV
Diazepam
Lorazepam
Midazolam
Benzo for febrile convulsions
Diazepam
How to get rid of barb
Alkalization
Sodium bicarbonate
Most common toxicity of bzd and barbiturates
Drowsiness and lethargy
Withdrawl of barbs
Anxiety and agitation
