1. Psychotic disorders Flashcards
Command hallucinations
auditory hallucinations that directly tell the pt to perform certain acts
Delusion vs. Illusion vs. hallucination
Delusion = false belief that cannot be altered Illusion = misinterpretation of an EXISTING sensory stimulus (such as mistaking a shadow for a cat) Hallucinations = sensory perception WITHOUT an actual external stimulus
Most commonly exhibited hallucination exhibited by schiz pts?
Auditory
DDx of psychosis secondary to general medical condition (4 categories)
- CNS disease (ex. MS, neoplasm, Alzheimer, Parkinson, Huntington chorea, tertiary syphilis, temporal lobe epilepsy, encephalitis, prion disease, neurosarcoidosis, AIDS)
- Endocrinopathies (Addison/Cushing disease, hyper/hypothyroidism, hyper/hypocalcemia, hypopituitarism)
- Nutritional/vit deficiency states (B12, folate, niacin)
- Other (SLE, temporal arteritis, porphyria)
What is delirium?
Acute confusional state
Work-up needed when pt with suspected schiz comes in
TSH, rapid plasma reagin (RPR), brain imaging, urine/serum drug screening
5 A’s of schiz (negative symptoms)
- Anhedonia
- Affect (flat)
- Alogia (poverty of speech)
- Avolition (apathy)
- Attention (poor)
Ecolalia vs. Echopraxia
Ecolalia = repeats words or phrases Echopraxia = mimics behavior (PRActices behavior)
Time differences b/w psychotic disorder, schizophreniform disorder, schizophrenia
Brief psychotic disorder = < 1month
Schizophreniform = 1-6 months
Schizophrenia = > 6months
Schizophrenics psych exam findings
- disheveled appearance
- flattened affect
- disorganized thought process
- intact memory and orientation!!
- auditory hallucinations
- paranoid delusions
- ideas of reference
- concrete understanding of similarities/proverbs
- lack insight into their disease
Lifetime prevalence of schiz?
1% over lifetime
Difference in men and women affected by schiz
equally affected by diff. presentations and outcomes
- men = present around 20 yo; more negative symptoms, more impaired social functioning
- women = present around 30 yo
Genetic predisposition of schiz
- 50% concordance among monozygotic twins
- 40% risk if both parents have sciz
- 12% risk if one 1st degree relative is affected
Comorbidity with schiz?
substance abuse
- alcohol (30-50%)
- cannabis (15-20%)
- cocaine (5-10%)
Downward drift hypothesis?
ppl suffering from schiz are unable to function well in society, thus enter lower socioeconomic groups