1. Nutrition, Diet And Body Weight 2 Flashcards

1
Q

What are Dietary Reference Values (DRVs)?

A
  • Estimates of the amount of energy and nutrients needed by different groups of healthy UK population.
  • Values depend on age, gender and level of physical activity.
  • Published by SACN (Scientific Advisory Committee on Nutrition).
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2
Q

What are the different types of DRVs?

A
  • Estimated Average Requirement (EAR): used for energy.
  • Reference Nutrient Intake (RNI): used for proteins, vitamins and minerals.
  • Lower Reference Nutrient Intake (LRNI): intakes below are insufficient for most people.
  • Safe intake: used when insufficient data.
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3
Q

What % of each studied group is EAR, RNI and LRNI appropriate for?

A
  • EAR: requirement for ~50% of group (50% will require more).
  • RNI: requirement for 97% of group (many will need less).
  • LRNI: requirement for those 2.5% who have low requirements (majority will need more).
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4
Q

What does an individual’s energy requirements depend on?

A

Age, sex, body composition and physical activity.

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5
Q

With moderate physical activity, what is the daily energy expenditure of the average adult male and female?

A
  • 70 kg adult male: ~12,000 kJ/day

- 58 kg adult female: ~9,500 kJ/day

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6
Q

What is daily energy expenditure the sum of?

A
  1. Basal metabolic rate
  2. Diet-induced thermogenesis: energy required to process food
  3. Physical activity level
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7
Q

What are the functions of basal metabolic rate?

A

Maintains resting activities of the body:

  1. Maintenance of cells (ion transport across membranes, biochemical reactions)
  2. Organ function
  3. Maintenance of body temperature
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8
Q

What is the basal tone at rest of different organs?

A
  • Skeletal muscle: ~30% BMR
  • Brain: ~20% BMR
  • Liver: ~20% BMR
  • Heart: ~10% BMR
  • Other: ~20% BMR
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9
Q

Which factors affect BMR?

A
  1. Body size (surface area)
  2. Gender (males higher than females)
  3. Environmental temperature (increases in cold)
  4. Endocrine status (increased in hyperthyroidism)
  5. Body temperature (12% increase per degree)
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10
Q

What energy stores does the body rely on?

A
  1. Very short term energy stores of energy-rich molecules in muscle: few seconds worth.
  2. Carbohydrate stores for immediate use (e.g. Creatine phosphate for initial energy burst): mins-hrs depending on activity.
  3. Long term stores in adipose: ~40 days worth.
  4. Under extreme conditions, muscle proteins can also be converted to energy.
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11
Q

What is obesity?

A
  • Excessive fat accumulation in adipose tissue which impairs health.
  • Result of energy intake exceeding energy expenditure over a period of years.
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12
Q

What health problems is obesity associated with?

A

Increased risk of some cancers, cardiovascular disease and type 2 diabetes

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13
Q

How is BMI calculated?

A

BMI = weight (kg) / height2 (m2)

= kg/m2

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14
Q

How can individuals be classified according to their BMI?

A
<18.5 = underweight
18.5-24.9 = desirable weight
25-29.9 = overweight
30-34.9 = obese
>35 = severely obese
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15
Q

What is the major weakness of the BMI calculator? What is an alternative measurement?

A

Very muscular individuals may be wrongly classified as obese.
Alternative measurement = waist:hip ratio

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16
Q

Why is pattern of body fat distribution clinically important?

A

Greater proportion of fat in upper body (especially abdomen - apple shaped) compared with that on hips (pear shaped) associated with increased risk of:

  • insulin resistance
  • hyperinsulinism
  • type 2 diabetes
  • hypertension
  • hyperlipidaemia
  • stroke
  • premature death
17
Q

What is malnutrition?

A

Damage from low energy intake or deficiency in other nutrients.

18
Q

What is the difference between marasmus and kwashiorkor disease?

A
  • Marasmus = lack of calories and proteins

- Kwashiokor = protein deficiency resulting in oedema

19
Q

Why is oedeoma a symptom of kwashiokor’s?

A

Low protein intake… insufficient blood protein synthesis… decrease in plasma oncotic pressure… greater net flow of fluid into interstitium… oedema.

20
Q

What is the normal fasting plasma concentration of glucose?

A

3.3 - 6.0 mol/L