1 - Intro Flashcards
Which of the following collagen types is a major component of basal lamina and comprises 50% of all basal lamina proteins?
A. I B. II C. III D. IV E. VII
D
What type of epithelium lines the circled tubule?
A. Simple cuboidal B. Stratified cuboidal C. Simple columnar D. Simple squamous E. Stratified squamous
A
A 20-year-old, thin, lanky man, with very long limbs and digits, has been experience ever increasing chest pain. He goes to his physician who orders an MRI of the man’s chest. The imaging finds early evidence of aortic dissection and the physician decides to get genetic testing on the man to confirm his suspicion about his patient’s condition. The gene for which of the following proteins is most likely mutated?
A. Laminin B. Type I collagen C. Fibrillin D. Type IV collagen E. Type III collagen
C (I think - double check)
Hematoxylin is what kind of dye?
Basic
Eosin is what kind of dye?
Acidic
What do basic dyes bind to?
Phosphate groups of nucleic acids, sulfate groups of glycosaminoglycans and carboxyl groups of proteins
What do acidic dyes bind to?
Cationic groups in tissues - cells with lots of membranous organelles or intermediate filaments
What are the fibroblasts of tendons called?
Tendinocytes
Parietal cells & Chief cells - what stains what?
Parietal - acidophilic (mit & memb), Chief - basophilic (rER bc of synthesis of protein pepsinogen)
How does Collagen stain?
Acidophilic (bc of charged amino groups)
How does Hyaline cartilage stain?
Basophilic (sulfated proteoglycans)
What are the 3 ways Tubular sections can be cut?
Cross section, longitudinal section or oblique section
The pericardium that surround the hyaline cartilage is made up of?
Type I collagen
Neurons are very active and neuroglial cells are?
Far less active than neurons, their chromatin is heterochromatin (very basophilic)
