1. Homeostasis Basics Flashcards
What is homeostasis ?
Maintenance of a stable internal environment - controlling system that keep you internally environment constant
Dynamic equilibrium - to ensure cells function normally
Why is homeostasis important ?
Maintain temp / blood pH
Because ^ these factors affect enzymes activity and enzymes control metabolic reactions.
Maintain blood glucose concentration because cells need glucose for energy and blood glucose concentration affects water potential of blood
Temp on metabolic reactions
Rate of metabolic reactions increases when temp increases
More heat = more kinetic energy = molecules move faster = more likely substate molecules to collide with enzymes active site = energy of collation also increases = reaction
If temp gets too higher
Reaction stops
Vibrations break hydrogen bonds that hold enzyme in 3D shape
Active site changes shape so substate cannot bind - denatured - doesn’t function as catalyst
Temp too low
Enzyme activity is reduced
Slowing rate of metabolic reactions
Highest rate of enzyme activity in humans , what temp ?
37 degrees
pH
Too low or too high enzymes denature
Ironic and hydrogen bonds holding 3D shale are broken so active site changes and denatured
Optimum pH is highest rate of enzyme activity - more metabolic reactions - pH 7
How is pH calculated by
Based on conc of hydrogen ions in environment
More H+ the lower the pH will be - acidic
pH = - Log10 [H+]
Log10
Logarithmic scale
Each value on log scale using Log10 is ten times larger than the value before