1 - Global Health - Non Infectious Disease (Cancer) Flashcards
Leading Causes of Death Due to Infectious Diseases
Lower respiratory infections HIV/AIDS Diarrhoeal diseases Tuberculosis Malaria Measles
Leading causes of death due to non-infectious diseases
heart diseases cerebro-vascular disease respiratory infections HIV/AIDS COPD (in 3rd world countries, mortality due to malnutrition/deficiencies)
Epidemiological transition
changes in levels and causes of mortality
decline in total mortality, and a significant reduction in infectious and deficiency diseases, which increase the relative role of chronic non-communicable diseases like cancers, cardiovascular and chronic respiratory disease, and diabetes
transition is complex and dynamic: the health and disease patterns of a society evolve in diverse ways as a result of demographic, socioeconomic, technological, cultural, environmental and biological changes
continuous transformation process, with some diseases disappearing and others appearing or re-emerging. There are some outstanding examples, such as the emergence of new infectious diseases like AIDS, the increase in infections that were previously controlled, such as tuberculosis and dengue fever, the decline
in stomach cancer and the rise and fall of lung cancer, and the shift from stroke to heart disease
Which measure of disease occurrence can be obtained from cross sectional studies?
prevalence
Prevalence
Prevalence is the frequency of a disease in a population at a point in time; hence it is often called point prevalence
Prevalence is a proportion. It is the only measure of disease occurrence that can be obtained from cross sectional studies. It measures the burden of disease in a population.
Prevalence
measures status (a condition: a subject affected by a specific disease)
prevalence is dependant on the incidence and the duration of disease (incidence x duration)
Prevalent cases include both new (incident) and existing cases
Epidemiology
ability to quantify the occurrence of disease in populations
Incidence
Incidence quantifies the number of new cases of a disease within a specified time interval. Incidence measures events (a change from a healthy state to a diseased state).
Mortality
number of deaths attributed to a specific condition in a given time period
Morbidity
number of cases of ill health, complications, side effects attributed to a particular condition over a particular time period
Most commonly diagnosed cancers
Lung
breast
colorectal
most common causes of cancer death
lung
liver
stomach
largest preventable cause of cancer
smoking
which may become more important contributors to cancer rates than infections in some countries?
smoking
overweight
Examples of non-communicable diseases
cancers
cardiovascular disease
chronic respiratory disease
diabetes
leading cause of death in sub-Saharan Africa
infectious diseases