1-3 Macrophage and Dendritic Cell Subsets

Question 1

Antigen-presenting cells

Answer 1

Cells capable of displaying antigen for recognition by T cells and of activating naïve T cells. Dendritic cells are antigen-presenting cells.

Question 2

Alveolar macrophages

Answer 2

Macrophages in the lungs.

Question 3

Dermal dendritic cells

Answer 3

Immature dendritic cells resident in the dermal layer of the skin: they are the interstitial dendritic cells of skin.

Question 4

Interstitial dendritic cells

Answer 4

Immature dendritic cells in the peripheral tissues, mucosa or dermal layers of the skin. Also know as tissue-resident dendritic cells.

Question 5

Kupffer cells

Answer 5

Macrophages in the liver.

Question 6

Langerhans cells

Answer 6

Immature dendritic cells in the epidermal layers of the skin.

Question 7

Microglia

Answer 7

Prevalent type of macrophages in the brain, characterized by long processes.

Question 8

Plasmacytoid dendritic cells

Answer 8

Cell type of the dendritic cell family that circulates in the blood, like plasma cells, and produces very large amounts of type 1 interferons upon contact with viruses.

Question 9

Immature dendritic cells

Answer 9

Dendritic cells that have not come into contact with a pathogen.