1 (16) Hormones Flashcards
Where is ADH produced?
hypothalamus
What is the effect of ADH?
more water is reabsorbed into the body and less urine is formed
What is the target of ADH?
kidneys
How is ADH regulated?
blood volume or the concentration of water in the blood
Where is oxytocin produced?
hypothalamus
What is the effect of oxytocin?
stimulates contraction of uterus during labor and milk “let down” or ejection from alveoli into ducts
What is the target of oxytocin?
mammary alveoli
How is oxytocin regulated?
positive-feedback mechanism where release of the hormone causes an action that stimulates more of its own release
Where is growth hormone produced?
anterior pituitary
What is the effect of growth hormone?
growth of essentially all tissues of the body, including bone
What is the target of growth hormone?
thymus gland
How is growth hormone regulated?
growth hormone-releasing hormone and growth hormone-inhibitory hormone
Where is prolactin produced?
anterior pituitary
What is the effect of prolactin?
responsible for breast development during pregnancy
What is the target of prolactin?
mammary gland
How is prolactin regulated?
dopamine (decreases) and estrogen (increases)
Where is thyroid stimulating hormone produced?
anterior pituitary
What is the effect of thyroid stimulating hormone?
stimulates thyroid gland to produce its hormones
What is the target of thyroid stimulating hormone?
thyroid gland
How is thyroid stimulating hormone regulated?
negative-feedback of thyroid hormones
Where is adrenocorticotropic hormone produced?
anterior pituitary
What is the effect of adrenocorticotropic hormone?
causes adrenal cortex to produce larger amounts of its hormones, especially cortisol
What is the target of adrenocorticotropic hormone?
adrenal cortex
How is adrenocorticotropic hormone regulated?
glucocorticoid feedback
Where is melanocyte stimulating hormone produced?
intermediate lobe of the pituitary
What is the effect of melanocyte stimulating hormone?
protecting the skin from UV rays, development of pigmentation and control of appetite
What is the target of melanocyte stimulating hormone?
skin
How is melanocyte stimulating hormone regulated?
exposure to UV light
Where is follicle stimulating hormone produced?
anterior pituitary
What is the target of follicle stimulating hormone?
gonads
Where is luteinizing hormone produced?
anterior pituitary
What is the target of luteinizing hormone?
gonads
Where is T4 and T3 produced?
thyroid gland
What is the effect of T4 and T3?
controls basal metabolic rate, regulates tissue growth and development, reactivity of nervous system
What is the target of T4 and T3?
virtually every cell in the body
How is T4 and T3 regulated?
thyroid stimulating hormone
Where is calcitonin produced?
thyroid gland
What is the effect of calcitonin?
inhibits osteoclasts and accelerates the uptake of Ca2+ and P into bones; increases loss of these minerals in urine
What is the target of calcitonin?
bones
How is calcitonin regulated?
hight levels of calcium in the blood
Where is parathyroid hormone produced?
parathyroid gland
What is the effect of parathyroid hormone?
increases osteoclast activity so Ca2+ and P are released into the blood; stimulates kidneys to release more Ca2+ and secrete more P
What is the target of parathyroid hormone?
bones and kidneys
How is parathyroid hormone regulated?
low levels of calcium in the blood
Where is aldosterone produced?
adrenal cortex
What is the effect of aldosterone?
increases absorption of Na+ and water and increase the secretion of K+ in the urine
What is the target of aldosterone?
kidneys
How is aldosterone regulated?
K+ levels in the blood and by renin-angiotensin aldosterone pathways
Where is cortisol produced?
adrenal cortex
What is the effect of cortisol?
promotes breakdown of fat and protein, lipolysis, gluconeogenesis, promotes stress resistance, and inhibits the immune response
What is the target of cortisol?
most body cells
How is cortisol regulated?
ACTH
Where is glucagon produced?
islet cells in pancreas
What is the effect of glucagon?
increases blood glucose
What is the target of glucagon?
liver and adipose tissue
How is glucagon regulated?
low blood glucose levels, sympathetic nervous system
Where is insulin produced?
islet cells in pancreas
What is the effect of insulin?
decreases blood glucose
What is the target of insulin?
most cells in body
How is insulin regulated?
increased blood glucose, PSNS
Where is melatonin produced?
pineal gland
What is the effect of melatonin?
diurnal cycles, possible anti-aging, production of antioxidants
What is the target of melatonin?
not known well
How is melatonin regulated?
input from visual pathways concerning visual intensity of light
Where is atrial natriuretic peptide produced?
right atrium of heart
What is the effect of atrial natriuretic peptide?
Na+ and water to be excreted into the urine
What is the target of atrial natriuretic peptide?
veins
How is atrial natriuretic peptide regulated?
central venous pressure