(1-11-17) History of Nitrous Oxide Flashcards

1
Q

what was surgery like before anesthesia?

A
  • painful
  • short
  • last resort

*was accepted as an inescapable aspect of necessary treatment

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2
Q

what was civilian surgery like in the 1800’s?

A
  • 333 surgeries were recorded at Mass. general hospital (about one a month)
  • operations lasted btw 5 and 15 minutes
  • surgery was used to treat otherwise hopeless cases

*physicians used sopoforics, narcotics, hypnosis, counterirritants (stinging), and uncounciousness (blow to the jaw)

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3
Q

what was introduced in 1844 that was considered state of the art?

A
  • opium
  • *large side-effects and dangerous
  • *not sufficient to eliminate pts response
  • alcohol
  • *stupefaction-inducing dose had serious side effect like nausea, vomitting, and death
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4
Q

lived from 1733-1804

  • co-discoverer of oxygen
  • discovered nitrous oxide in 1774
  • did NOT pursue medical uses of gases
A

Joseph Priestley

(also was an outspoken supporter of american and french revolutions, controversial unitarian minister, invented carbonated beverages)

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5
Q
  • surgical apprentice in 1795
  • in 1798 became superintendent of The Pneumatic Institute
  • research focused on pulmonary TB tx with gases
  • tried nitrous oxide on himself
A

Humphry Davy

*cauderized a dog bite wound on his own leg, without nitrous oxide

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6
Q

Considered the Father of Laughing Gas

*he is the one that suggested that nitrous oxide could be used to alleviate the pain of surgery

A

Humphry Davy

*this is because he described the feeling of Nitrous Oxide as an agreeable sense of giddiness

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7
Q

why was humphry davy’s suggestion that nitrous oxide should be used for medicine ignored?

A

bc it was already becoming a recreational drug and not viewed seriously

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8
Q
  • a large competitor to nitrous oxide
  • used “animal magnetism” to hypnotize subjects
  • very popular in vienna then paris
  • sponsored by marie antoinette after he moved to paris
A

Franz Anton Mesmer

*left Vienna in 1778 after being branded a fraud

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9
Q

T/F nitrous oxide capers appeared in traveling medicine shows and carnivals

A

TRUE

  • public would pay to inhale a minutes worth of the gas
  • laugh and act silly until the effect of the drug ended, then stand about in confusion
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10
Q

med school dropout that promulgated nitrous oxide in america

A

gardner quincy colton

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11
Q

discoverer of anesthesia

A

Dr, Horace Wells

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12
Q

what occured in Dr. Well’s Epiphany?

A
  • Well’s learns that Cooley was unaware of the injury until after the nitrous effect ended, and RECOGNIZES THE IMPORTANCE
  • he persuades Dr. Colton to come to his office for an experiment
  • the next day, while under nitrous oxide, Wells was his own molar removed painlessly by another dentist
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13
Q

How did the presentation of Well’s epiphany go?

A

poorly

  • during the procedure, the pt cried out
  • Wells was booed and hissed from the room as a humbug

*when asked later though, the pt had no memory of the surgery

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14
Q
  • trainee and partner of Horace Wells
  • was present at Wells’ failed demonstration
  • continued experimenting with anesthesia using ether
A

Dr. William T.G. Morton

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15
Q

what and when was the first SUCCESSFUL demonstration of anesthesia

A
  • oct. 16th, 1846
  • Morton anesthetized the pt with inhaled ether
  • Dr. JC Warren removed a tumor from the neck of a pt that was unresponsive
  • Warren pronounced the anesthetic a success “Gentlemen, this is no humbug”

*pt later stated that the incision felt like a hoe was dragged across his neck

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16
Q

what happened to Horace Wells?

A
  • never recovered from his humiliation
  • continued to practice, using nitrous oxide and other gases
  • became addicted to chloroform
  • was incarcerated for attacking a prostitute
  • committed suicide in 1848, unrecognized

*nitrous oxide lost favor after Well’s death and was NOT widely used in medicine

17
Q

in 1847, what did James Simpson develop to anesthetize women during delevery?

A

chloroform

*initial experiment performed in his dining room

18
Q

in Nitrous Oxide the only one of these original gases still in use today?

A

yes

19
Q

what type of sedation does nitrous oxide provide?

A

conscious sedation

20
Q

is nitrous oxide common?

A

YES

*most commonly used anesthetic gas for GA in combo with another agent