09/02/2015 Lecture Flashcards
When is the neonatal period?
first 28 days of life
What are the two major systems that have to adapt during the neonatal period?
1) Respiratory System
2) Cardiovascular system
- most transitions happen within first 6-10 hours
Where is the site of gas exchange for the fetus? for the newborn?
1) fetus - placenta
2) newborn - lungs
What happens to the newborn’s circulatory system after birth?
3 shunts close up (ductus venosis, foramen ovale, ductus arteriosis), umbilical arteries/vein gone
what does the ductus venosis do? foramen ovale (why is this important)? ductus arteriosis?
1) bypass the liver
2) puts blood directly into left atrium to circumvent pulmonary circuit (blood then goes into left ventricle and into left aorta) -> allows blood to get to baby’s body as efficiently as possible b/c lungs don’t work yet
3) connects pulmonary artery to aorta allowing blood to bypass pulmonary circuit
What is the umbilical vein?
carries o2 blood from placenta to fetus
what is PDA?
patent ductus arteriosis, means it never closed when transition cardiovasc system from fetal to newborn
what will HR be for first half-hour of life?
160-180 HR
Newborn heart rate should be how many BPM? What should you be able to palpate in newborn?
at LEAST 100, should be able to palpate PMI at 3rd or 4th intercostal space and left of midclavicular line; pulses 2+ is normal
Is it normal to have a transient normal in newborn?
yes, wooshing sound from foramen ovale still closing off and you’re hearing the result of that
What is blood volume dependent on in newborn
- amount transferred from placenta at birth
- when the physician clamps the umbilical cord (early, 3 minutes
is late or early cord clamping beneficial?
late, anemia precention, increased BP, improve cardiopulmonary adaptation, improved o2 transport and RBC flow
What is nature’s first stem cell transplant?
cord blood, can potentiate into any cells the body needs
Newborn Blood values
Hg: 17-23 gm/dL Hct: 46-86% Platelets: 100k - 350k RBC: 4.5-7.0 WBC: 10-30k (elevation from trauma of going through birth)
What are the respiratory system adaptations?
1) surfactant: lipoprotein that will keep alveoli from collapsing
2) initiation of respirations: adjusting from flui-filled intrauterine enviro to gaseous extrauterine
Who has the most trouble making initial respirations?
- premature babies, baby’s not delivered vaginally
How does a vaginal birth help with respiratoins?
- coming out the baby’s lungs get squeezed and when outside of the uterus, the lungs naturally expand and suck in air and help to initiate first breath
What are environmental stimuli that help kickstart the baby’s systems?
- lighting
- sound
- temperature
- wet to dry
what’s the measurement of blood gases in the newborn like?
higher CO2 level and lower O2 concentration of blood
What are the signs of resp distress in the newborn?
1) nasal flaring
2) Intercostal or subcostal retractions
3) Grunting: a little bit more like a sigh/small fart sound/laboured exhale
4) Chest and abdomen not moving together with breathing (See-saw respirations)
How do we classify apnea in the newborn?
- periods of apnea have to be greater than 15 seconds, because the newborn has very abnormal breathing patterns which is normal (called periodic breathing)
What’s the normal respiratory rate for the newborn?
30-60 breaths/minute
how do newborns thermoregulate?
heat production: primarily through non-shivering thermogenesis
heat loss: caused by lots of factors
- thin skin with vessels close to surface
- little subQ fat
- can’t change posture
can newborns shiver?
not really, limited stores of metabolic substrates
do newborns have a large body surface area? what does that mean?
yes, large SA in terms of body weight, means lots of heat loss
what are the 4 mechanisms of heat loss for the newborn?
1) conduction (contact)
2) Convection (air)
3) evaporation (water evaporation, why we dry babies)
4) radiation (cold exterior spaces like cold walls/windows)
what can hypothermia in the baby cause in a newborn?
cold stress
What can cold stress cuase?
1) respiratory distress: to produce heat there’s an increase in need for O2 to raise body temp, so increased RR, pulmonary vasoconstriction can occur and blood pH goes down
2) exacerbate hyperbilirubinemia: more anaerobic glycolysis leads to increase production of acids which displace bilirubin from albumin-binding sites
3) hypoglycemia: anaerobic glycolysis uses more blood glucose which depletes them
what is brown fat?
specialized type of fat in babies that is very vasculature and can help boost heat BUT there’s very little of it so can be burnt through quickly
To create heat what do babies need to put into their bodies? what does this cause?
O2, higher RR
What’s the best way to maintain temperature in a newborn?
skin-to-skin with mom or dad (can then cover baby with a blanket)
*** if mom or dad not there put them under radiator warmer in nursery
what is thermogenesis
- an attempt to generate heat
<p>what are the two causes of hypothermia ***need to look up if it's hyperthermia on slides***(s/s?)</p>
<p>1) environmental cause - skin vessel dilate and appears flushed - skin is warm to touch - infant's posture is of extension 2) sepsis causation - skin vessel constrict and baby appears pale - hands and feet are cool to the touch</p>
so when the placenta is lost at birth, the maternal glucose supply is cut off (baby’s glucose = 70-80% of mom’s), what organ compensates for this in the first 24 hours of life?
the liver releases glucose from glycogen stores
- initiate early feeding assistance
What are the three different ways jaundice can happen in newborn?
1) overproduction of bilirubin
- RBCs being broken down very fast in newborn release heme groups resulting in increased levels of bilirubin
2) decreased conjugation
- not being made into form that the body can excrete, indirect or fat-soluble bilirubing needs to be made into a form that’s water-soluble to be excreted
3) impaired exretion
for how long can a newborn’s iron stores last for?
4-6 months