(04) Tranquilizers, sedatives, etc

Question 1

1. 1. Acetylpromazine is a commonly used sedative in canine and equine medicine - inhibiting what receptors?

also has what activity that can be useful?

Answer 1

1. dopaminergic, serotonergic and noradrenergic receptors

anticholinergic and antihistaminic activity

Question 2

1. 2. Acetylpromazine is useful in combination with ketamine beause what?

ace is likely to cause what?

Answer 2

it has some anticholinergic activity and thus helps prevent salivation, potentiates the depressant effect and inhibits the excitatory effects, minimizes the dose of ketamine required and thus its side effects and produces less respiratory depression than other preanesthetics.

catalepsy

Question 3

1. What is a catecholamine that should be used instead of epinephrine to maintain blood pressure

Answer 3

1. NE

Question 4

1. What is a sedative and a potent antiemetic compound used frequentlyl to prevent motion sickness.

Answer 4

Droperidol

Question 5

1. What at low doses is a commonly used emetic in feline medicine and at higher doses it is a useful sedative?
2. It may transiently increase what prior to achieving tits longer term sedative and hypotensive effects?

Answer 5

1. xylazine
2. BP

(Xylazine has a mechanism of action that has little in common with other sedatives and muscle relaxants.)

Question 6

1. What is frequently used in equine field anesthesia as an adjunct to anesthesia with good sedative, skeletal muscle relaxant and analgesic activity ?

is also a useful what?

Answer 6

1. Guaifenesin (GGE)

expectorant