(03) Anticonvulsants

Question 1

1. what is a general anticonvulsant at a sedative dose and useful in status epilepticus
2. can it be used for feline epilepsy?
3. is it a sedative/muscle relaxant?
4. mech?

Answer 1

1. diazepem
2. yes
3. yes
4. allosterically potentiates Cl- flux through GABA receptor complexes.

Question 2

1. Acetylpromazine inhibits excitability induced by what?

exacerbates effect of what?

also inhibits what?

Answer 2

1. ketamine

strychnine

apomorphine induced emesis

Question 3

1. what is useful in forms of canine epilepsy that are not adequately controlled by phenobarbital?

Answer 3

1. phenytoin

(Unfortunately this drug is not a general anticonvulsant and therefore cannot be used for all seizures)

Question 4

1. What is an anticonvulsant that is unique as it does not produce CNS depression and actually controls the unique pain associated with neuralgias and neuromas.

Answer 4

Carbamazepine