031 Principles of Metabolic Regulation Flashcards
1
Q
What is the most common type of covalent modification and which enzyme does it use?
A
Phosphorylation by kinases
2
Q
Which enzymes catalyze dephosphorylation?
A
Phosphoprotein phosphatases
3
Q
What is allosteric control?
A
The reversible, non-covalent binding of effectors to enzymes resulting in activation or inhibition. This can happen within seconds.
4
Q
How do allosteric effectors worked?
A
By stabilising effect between the tense and rest state.
5
Q
What are conserved metabolites?
A
When substrates are just being recycled around e.g. ATP but the total concentration of both forms is unchanged.
6
Q
What are secondary messengers within the cell?
A
They amplify the effect of hormone binding, so a small quantity is required.
