03 - injectable anesthetic agents

Question 1

(Ideal injectable agent)

1. rapid onset, recovery
2. lack of tissue tox
3. lack of adverse cardio and resp effects
4. rapid metabolism
5. provides analgesia
6. provides muscle relaxation

Question 2

(barbitutates)

1. 2 examples?
2. which is fat soluble? what is not as fat soluble?

Answer 2

1. thiopental and pentobarbital
2. thiopental (is redistributed), penotobarbital (depends on metabolism)

Question 3

(barbiturates)

(thiopental)

1. effect on breathing?
2. effect on CV?

Answer 3

1. depressed (briep apnea seen after administration)
2. causes reduced CO

(be careful in animals with cardiac disease)

Question 4

(cyclohexamines)

1. like what?
2. animal appears awake but unaware of surroundings, sensitive to sound, rigid muscles
3. better visceral or somatic anaglesia?

Answer 4

1. ketamine
2. somatic

Question 5

(cyclohexamines - ketamine)

1. usually mixed with what for IV use?
2. ketamine + what IM in cats can be used for restraint and minor procedures?

Answer 5

1. diazepam
2. xylazine

Question 6

(cyclohexamines: ketamine)

(disadvantages)

1. no reversal
2. CV effects?
3. resp effects?

Answer 6

2. hypertension, tachycardia
3. apneustic breathing (abnormal breathing)

Question 7

(propofol)

1. how is it given?
2. CV effects?
3. resp effects?
4. premedication required?

Answer 7

1. administered slowly IV
2. hypotension or tachycardia
3. bradycardia
4. strongly recommended

Question 8

(etomidate)

1. sedative and hypnotic
2. short acting, good muscle relaxation, but no what?
3. advantages?
4. disadvantages?

Answer 8

2. analgesia
3. can give repeat doses, minimal CV/hepatic fx, works well in sick animals
4. suppresses adrenal fxn

nausea, vomiting, excitment during induction