03 - Biological Buffers And Transport Flashcards

1
Q

What is an acid?

A

A chemical substance that can donate a hydrogen ion

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2
Q

What is a base?

A

A chemical substance that can accept a hydrogen ion

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3
Q

What is true about a strong acid?

A

It completely dissociates or ionises in solution

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4
Q

What is true about a weak acid?

A

It partially dissociates or ionises in solution

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5
Q

What is an acid base buffer?

A

A solution consisting of two or more chemical compounds that resist large changes in hydrogen ion concentration when either an acid or base is added to the solution

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6
Q

What does a buffer have the ability to do?

A

Bind or release protons in solution, thereby keeping the pH of the solution relatively constant

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7
Q

What is the normal plasma pH range?

A

7.35 - 7.45

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8
Q

When does acidosis occur?

A

When pH falls below 7.35

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9
Q

When does alkalois occur?

A

When ph rises above 7.45

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10
Q

What do acid base buffer systems immediately combine with?

A

Any acid or alkali

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11
Q

What is the major buffering system in extracellular fluid?

A

The bicarbonate system buffer

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12
Q

What is an important buffering system in both intracellular and extracellular fluids

A

The protein buffer system

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13
Q

What is the important buffering system in intracellular fluid and major buffer in urine?

A

Phosphate buffer system

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14
Q

What organ/ organism does this… excretes acid or alkaline urine which enables changes to be made by the … in response to alterations in plasma pH

A

Kidneys

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15
Q

What is the bicarbonate buffer system made of?

A

Weak acid, carbonic acid and its conjugate base , the bicarbonate ion

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16
Q

What is the bicarbonate buffer system responsible for?

A

The buffering and removal of metabolic acids from the body

17
Q

Where are protons buffered within

A

RBC by haemoglobin

18
Q

Does haemoglobin have a larger buffering capacity than plasma proteins?

A

Yes - 6 times more

19
Q

What is the pH of intracellular fluid?

A

7.2

20
Q

What exposes the cytoplasm to changes in pH

A

Metabolic reactions within the cell